Enalapril maleate synthesis
- Product Name:Enalapril maleate
- CAS Number:76095-16-4
- Molecular formula:C24H32N2O9
- Molecular Weight:492.52
![N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine](/CAS/GIF/82717-96-2.gif)
82717-96-2
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76095-16-4
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Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: HCl / CH2Cl2; dioxane / -5 - 0 °C
1.2: ClCOCOCl / dimethylformamide; CH2Cl2; dioxane / -5 - 0 °C
2.1: dimethylformamide; CH2Cl2; dioxane / 1 h / 20 °C
3.1: DBU / acetonitrile; CH2Cl2 / 8 h / 20 °C
3.2: 92 percent / ethyl acetate / 3 h / 20 °C
References:
Palomo, Claudio;Palomo, Antonio L;Palomo, Francisco;Mielgo, Antonia [Organic letters,2002,vol. 4,# 23,p. 4005 - 4008]
75847-73-3
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110-16-7
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76095-16-4
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110-16-7
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147-85-3
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![Benzenebutanoic acid, α-[[(1S)-1-methyl-2-[[(1-methylethylidene)amino]oxy]-2-oxoethyl]amino]-, ethyl ester, (αS)-](/CAS/20210305/GIF/406213-94-3.gif)
406213-94-3
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76095-16-4
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103377-40-8
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76095-16-4
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64920-29-2
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76095-16-4
554 suppliers
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