| Identification | More | [Name]
Anthranilic acid | [CAS]
118-92-3 | [Synonyms]
1-AMINO-2-CARBOXYBENZENE
2-AMINOBENZOIC ACID
2-ANTHRANILIC ACID
2-CARBOXYANILINE
AKOS BBS-00003782
ANTHRANILIC ACID
H-2-ABZ-OH
H-ANT-OH
O-AMINOBENZOIC ACID
RARECHEM AL BO 0225
TIMTEC-BB SBB007560
VITAMIN L1
2-Aminobenzoesαure
2-amino-benzoicaci
Anthranic acid
anthranilic
Anthranilsαure
Benzoic acid, 2-amino-
Benzoic acid, o-amino-
Benzoicacid,2-amino | [EINECS(EC#)]
204-287-5 | [Molecular Formula]
C7H7NO2 | [MDL Number]
MFCD00007712 | [Molecular Weight]
137.14 | [MOL File]
118-92-3.mol |
| Chemical Properties | Back Directory | [Appearance]
White to off white crystalline powder | [Melting point ]
144-148 °C(lit.) | [Boiling point ]
251.96°C (rough estimate) | [density ]
1.412 | [vapor density ]
4.7 (vs air)
| [vapor pressure ]
0.1Pa at 52.6℃ | [refractive index ]
1.5323 (estimate) | [Fp ]
150°C | [storage temp. ]
Store at 0°C | [solubility ]
ethanol: may be clear to slightly hazy
| [form ]
powder | [pka]
2.108(at 25℃) | [color ]
White to pale yellow crystalline | [PH Range]
Non-B uorescence (1.5) light blue B uorescence (3.0) | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
5.7 g/L (25 ºC) | [Merck ]
14,422 | [BRN ]
471803 | [Major Application]
bottom antireflective coatings, semiconductor devices, inks, hair dyes, cosmetics, treatment of chronic inflammatory diseases, depression | [LogP]
0.99 at 23℃ and pH3.7 | [Uses]
Dyes, drugs, perfumes, and pharmaceuticals.
| [CAS DataBase Reference]
118-92-3(CAS DataBase Reference) | [IARC]
3 (Vol. 16, Sup 7) 1987 | [NIST Chemistry Reference]
Anthranilic acid(118-92-3) | [EPA Substance Registry System]
118-92-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes.
R37:Irritating to the respiratory system.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S39:Wear eye/face protection . | [WGK Germany ]
2
| [RTECS ]
CB2450000
| [TSCA ]
Yes | [HS Code ]
29224300 | [Safety Profile]
Moderately toxic by
ingestion and intraperitoneal routes.
Experimental reproductive effects. Human
mutation data reported. Questionable
carcinogen with experimental tumorigenic
data. Combustible. When heated to
decomposition it emits toxic fumes of NOx. | [Hazardous Substances Data]
118-92-3(Hazardous Substances Data) |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Sodium hydroxide-->Hydrochloric acid-->Sulfuric acid-->Ammonium hydroxide-->Chlorine-->Sodium hypochlorite-->Phthalic anhydride-->Water-->Activated carbon-->Sodium benzoate | [Preparation Products]
2-Iodobenzoic acid-->2-Fluorobenzoic acid-->4-CHLORO-QUINAZOLINE-->N-Phenylanthranilic acid-->2-Amino-5-iodobenzoic acid-->2-Chlorothioxanthone-->Clozapine-->Methyl Red-->1,3-BENZODITHIOLYLIUM TETRAFLUOROBORATE-->6-Iodoquinazolin-4-one-->2-CHLORO-9-(3-(DIMETHYLAMINO)PROPYL)-TH&-->2-Hydrazinobenzoic acid hydrochloride-->4-Hydroxyquinazoline-->Copper, 2,2'-[carbonylbis[imino(1-hydroxy-3-sulfo-6,2-naphthalenediyl)azo]]bis[benzoic acid] complex-->3-Indazolinone-->6,10,12-trichloronaphth[2,3-c]acridine-5,8,14(13H)-trione-->2-DIMETHYLAMINOBENZOIC ACID-->Fluorescent Brightener Pf-->9-AMINOACRIDINE-->Lobenzarit-->2-Amino-5-bromobenzoic acid-->ETHYL ANTHRANILATE-->4-hydroxy-1-methyl-3-[(3-nitrophenyl)azo]-2-quinolone-->Reactive Blue X-R-->1-Benzyl-3-hydroxy-1H-indazole-->Benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul-->trisodium [mu-[2-[[1-hydroxy-6-[[[[5-hydroxy-6-[(2-hydroxy-5-sulphophenyl)azo]-7-sulpho-2-naphthyl]amino]carbonyl]amino]-3-sulpho-2-naphthyl]azo]benzoato(7-)]]dicuprate(3-)-->N-BENZYLANTHRANILIC ACID-->Vat Red 41-->2-(4-chlorophenylthio)benzoic acid-->Phenylethyl Anthranilate-->N-Acetylanthranilic acid-->3,5-Dibromobenzoic acid-->2,5-Dibromobenzoic acid-->Tranilast-->PHENAZINE-1-CARBOXYLIC ACID-->2,2'-Dithiosalicylic acid-->barium(2+) hydrogen 2-[(2-hydroxy-3,6-disulphonato-1-naphthyl)azo]benzoate-->N-(2-CARBOXYPHENYL)GLYCINE |
| Hazard Information | Back Directory | [General Description]
Odorless white to pale-yellow or tan crystalline powder with a sweetish taste. | [Reactivity Profile]
ANTHRANILIC ACID(118-92-3) is incompatible with strong oxidizers. | [Air & Water Reactions]
This chemical may be sensitive to prolonged exposure to air and light. Insoluble in water. | [Hazard]
Questionable carcinogen. | [Fire Hazard]
This chemical is combustible. | [Chemical Properties]
White to off white crystalline powder | [Application]
2-Aminobenzoic acid is called vitamin L1; it enhances the milk production of cows. The major use of 2-aminobenzoic acid is as an intermediate for dyes. As its occurrence suggests, it is an intermediate for indigo synthesis. Mordant Brown 40 and Vat Violet 13 are other derivatives. 4-Hydroxy-1-methyl-carbostyril [1677- 46-9] is an important derivative used in making dyes and pigments. Its methyl and ethyl esters are used as fragrances for toiletries. In the pharmaceutical industry, it is used as an intermediate for tranquilizers and antiphlogistics. | [Definition]
ChEBI: An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 29, p. 1159, 1981 DOI: 10.1248/cpb.29.1159
Journal of the American Chemical Society, 107, p. 5008, 1985 DOI: 10.1021/ja00303a038 | [Purification Methods]
Crystallise anthranilic acid from water (charcoal). It has also been recrystallised from 50% aqueous acetic acid. It sublimes in a vacuum. [Beilstein 14 IV 1004.] |
|