| Identification | More | [Name]
4,4,5,5,5-Pentafluoro-1-pentanol | [CAS]
148043-73-6 | [Synonyms]
4,4,5,5,5-PENTAFLUORO-1-PENTANOL
4,4,5,5,5-PENTAFLUOROPENTAN-1-OL
4,4,5,5,5-PENTAFLUOROPENTANOL
Pentafluoropentanol
4,4,5,5,5-Pentafluoropentan-1-ol 96%
4,4,5,5,5-Pentafluoropentan-1-ol96%
4,4,5,5,5-Pentafluoro-1-pentanol ,97% | [EINECS(EC#)]
421-360-9 | [Molecular Formula]
C5H7F5O | [MDL Number]
MFCD00153224 | [Molecular Weight]
178.1 | [MOL File]
148043-73-6.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F | [Risk Statements ]
R36:Irritating to the eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
1993 | [WGK Germany ]
2
| [Hazard Note ]
Irritant | [HazardClass ]
FLAMMABLE | [HS Code ]
29055900 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to yellow liquid | [Uses]
An intermediate in the preparation of pentafluoropentane-1-thiol: an important chain of anti-breast cancer agents. | [General Description]
4,4,5,5,5-Pentafluoro-1-pentanol(148043-73-6), also known as pentafluoropentanol, is a perfluorous solvent.
| [Synthesis]
Pentafluoroiodoethane could used as a starting material to synthesize 4,4,5,5,5-Pentafluoro-1-pentanol. Specific steps are as follows: under an inert gas atmosphere, iron acetylacetonate, 6,6'-dimethyl-2,2'-bipyridine, and 1,2-dichloroethane were added to the reactor, reacted at RT for 0.5 h; added allyl alcohol, cesium carbonate, pentafluoroiodoethane successively, triisopropylsilane, warmed up to 80 ℃ and reacted for 24 h. Sampling and detection confirmed that the reaction of allyl alcohol was complete, stopped the reaction, and cooled to room temperature. The excess pentafluoroiodoethane was recovered, nitrogen was introduced into the system, hydrochloric acid was added to quench the reaction, washed, separated to obtain an organic phase, distilled to remove the solvent, and rectified to obtain 4,4,5,5,5-pentafluoro Amyl alcohol. Yield: 90.4%.
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| Well-known Reagent Company Product Information | Back Directory | [Alfa Aesar]
4,4,5,5,5-Pentafluoropentanol, 94%(148043-73-6) | [Sigma Aldrich]
148043-73-6(sigmaaldrich) | [TCI AMERICA]
4,4,5,5,5-Pentafluoro-1-pentanol,>93.0%(GC)(148043-73-6) |
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