| Identification | More | [Name]
TRIMETHYLENE OXIDE | [CAS]
503-30-0 | [Synonyms]
1,3-EPOXYPROPAN
1,3-EPOXYPROPANE
1,3-PROPYLENE OXIDE
1,3-TRIMETHYLENE OXIDE
OXETANE
TRIMETHYLENE OXIDE
alpha,gamma-Propane oxide
alpha,gamma-propaneoxide
Cyclooxabutane
Oxacyclobutane
Oxetan
Propane, 1,3-epoxy-
Trimethylenoxid
Trimethyleneoxide,99%
Trimethyleneoxide,97%
3-AMINOMETHYL PHENYL SULFONE
OXECTANE | [EINECS(EC#)]
207-964-3 | [Molecular Formula]
C3H6O | [MDL Number]
MFCD00005167 | [Molecular Weight]
58.08 | [MOL File]
503-30-0.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS LIQUID | [Melting point ]
-97°C | [Boiling point ]
50 °C(lit.) | [density ]
0.893 g/mL at 25 °C(lit.)
| [vapor pressure ]
5.09 psi ( 20 °C)
| [refractive index ]
n20/D 1.392(lit.)
| [Fp ]
−19 °F
| [storage temp. ]
2-8°C
| [solubility ]
1000g/l | [form ]
Liquid | [color ]
Clear colorless | [Odor]
agreeable odor | [explosive limit]
2.4%(V) | [Water Solubility ]
Soluble in water. | [Merck ]
14,9715 | [BRN ]
102382 | [CAS DataBase Reference]
503-30-0(CAS DataBase Reference) | [EPA Substance Registry System]
Oxetane (503-30-0) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
R11:Highly Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S9:Keep container in a well-ventilated place .
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S29:Do not empty into drains . | [RIDADR ]
UN 1993 3/PG 2
| [WGK Germany ]
1
| [RTECS ]
RQ6825000
| [F ]
3-10-23 | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29329990 | [Safety Profile]
Moderately toxic by subcutaneous route. May be narcotic in high concentrations. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes | [Hazardous Substances Data]
503-30-0(Hazardous Substances Data) | [Toxicity]
mmo-sat 3333 mg/plate EMMUEG 11(Suppl 12),1,88 |
| Hazard Information | Back Directory | [General Description]
Clear, colorless liquid with an agreeable aromatic odor. | [Reactivity Profile]
1,3-PROPYLENE OXIDE(503-30-0) reacts with Grignard reagents and organolithium compounds. 1,3-PROPYLENE OXIDE(503-30-0) is also incompatible with oxidizing agents and strong acids. . An explosion occurred when propylene oxide was added to epoxy resin. Polymerization was catalyzed by amine accelerator in the resin [Bretherick 1995]. Propylene oxide and sodium hydroxide base-catalyzed the polymerization of the former, causing ignition and explosion of a drum of the crude product. [Combust Sci. Technol., 1983]. | [Air & Water Reactions]
Highly flammable. Water soluble. | [Fire Hazard]
This chemical is flammable. | [Chemical Properties]
CLEAR COLOURLESS LIQUID | [Uses]
Trimethylene oxide useful for the synthesis of 3-substituted propanols by reaction with Grignards or organolithiums in the presence of CuBr. | [Definition]
ChEBI: A saturated organic heteromonocyclic parent that is a four-membered ring comprising of three carbon atoms and an oxygen atom. | [Purification Methods]
Distil oxetane twice from sodium metal and then fractionate it through a small column at atmospheric pressure, b 47.0-47.2o. It can also be purified by preparative gas chromatography using a 2m silica gel column. Alternatively, add KOH pellets (50g for 100g of oxetane) and distil it through an efficient column or a column packed with 1/4in Berl Saddles with the main portion boiling at 45-50o being collected and redistilled over fused KOH. [Noller Org Synth Coll Vol III 835 1955, Dittmer et al. J Am Chem Soc 79 4431 1957, Beilstein 17 H 6, 17 I 3, 17 II 12, 17 III/IV 13, 17/1 V 11.] |
|
|