ChemicalBook--->CAS DataBase List--->5437-98-9

5437-98-9

5437-98-9 Structure

5437-98-9 Structure
IdentificationMore
[Name]

4'-Methoxyacetoacetanilide
[CAS]

5437-98-9
[Synonyms]

4'-methoxyacetoacetanilide
AAPA
ACETOACET-P-ANISIDIDE
ACETO ACET P-ANISIDINE
acetoacetyl-p-acetanisidine
AKOS B029142
N-(4-METHOXYPHENYL)-3-OXOBUTANAMIDE
N-(4-METHOXYPHENYL)-3-OXO-BUTYRAMIDE
N-ACETOACETYL-4-METHOXYANILINE
N-ACETOACETYL-P-ANISIDINE
P-ACETOACETANISIDE
P-ACETOACETANISIDIDE
4’-methoxy-acetoacetanilid
4-methoxyl-n-acetoacetanilide
Acetoacetanilide, 4'-methoxy-
alpha-APA
Butanamide, N-(4-methoxyphenyl)-3-oxo-
Butanamide, N-(4-methoxyphenyl)-oxo-
n-(4-methoxyphenyl)-3-oxo-butanamid
N-(4-Methoxyphenyl)acetoacetamide
[EINECS(EC#)]

226-615-6
[Molecular Formula]

C11H13NO3
[MDL Number]

MFCD00008783
[Molecular Weight]

207.23
[MOL File]

5437-98-9.mol
Chemical PropertiesBack Directory
[Appearance]

WHITE TO VERY SLIGHTLY YELLOW POWDER
[Melting point ]

115-118 °C
[Boiling point ]

346.25°C (rough estimate)
[density ]

1.1878 (rough estimate)
[vapor pressure ]

0.001Pa at 20℃
[refractive index ]

1.5100 (estimate)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Powder
[pka]

11.35±0.46(Predicted)
[color ]

White to Blue
[Water Solubility ]

soluble
[LogP]

0.85 at 23℃ and pH8.3-8.6
[CAS DataBase Reference]

5437-98-9(CAS DataBase Reference)
[NIST Chemistry Reference]

Butanamide, 3-oxo-n-(4-methoxyphenyl)-(5437-98-9)
[EPA Substance Registry System]

5437-98-9(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[RTECS ]

AK4598010
[HS Code ]

2924297099
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acetyl ketene
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

4'-Methoxyacetoacetanilide(5437-98-9).msds
Hazard InformationBack Directory
[Chemical Properties]

WHITE TO VERY SLIGHTLY YELLOW POWDER
[Uses]

N-(4-Methoxyphenyl)-3-oxobutanamide is an intermediate in the synthesis of Tafenoquine-d3 Succinate is the labelled analog of Tatenoquine (T004760), a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
[Synthesis Reference(s)]

The Journal of Organic Chemistry, 11, p. 803, 1946 DOI: 10.1021/jo01176a024
Spectrum DetailBack Directory
[Spectrum Detail]

4'-Methoxyacetoacetanilide(5437-98-9)MS
4'-Methoxyacetoacetanilide(5437-98-9)1HNMR
4'-Methoxyacetoacetanilide(5437-98-9)13CNMR
4'-Methoxyacetoacetanilide(5437-98-9)IR1
4'-Methoxyacetoacetanilide(5437-98-9)IR2
Well-known Reagent Company Product InformationBack Directory
[TCI AMERICA]

p-Acetoacetanisidide,>98.0%(N)(5437-98-9)
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