| Identification | More | [Name]
Daltroban | [CAS]
79094-20-5 | [Synonyms]
2-[4-[2-(4-chlorophenyl)sulfonylaminoethyl]phenyl]acetic acid
4-[2-[(4-CHLOROPHENYLSULFONYL)AMINO]ETHYL]BENZENEACETIC ACID
BM-13505
DALTROBAN
SKF-96148
DatelliptiumChloride
4-[2-[(4-Chlorophenylsulfonyl)amino]ethyl]benzeneacetic acid, BM-13505, SKF-96148
4-[2-(4-Chlorobenzene-sulfonamido)ethyl]benzeneacetic acid | [Molecular Formula]
C16H16ClNO4S | [MDL Number]
MFCD00868295 | [Molecular Weight]
353.82 | [MOL File]
79094-20-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
132.5-137.4 °C(lit.) | [Boiling point ]
555.3±60.0 °C(Predicted) | [density ]
1.378±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 22 mg/mL, soluble
| [form ]
A solid | [pka]
4.33±0.10(Predicted) | [color ]
white
| [InChI]
InChI=1S/C16H16ClNO4S/c17-14-5-7-15(8-6-14)23(21,22)18-10-9-12-1-3-13(4-2-12)11-16(19)20/h1-8,18H,9-11H2,(H,19,20) | [InChIKey]
IULOBWFWYDMECP-UHFFFAOYSA-N | [SMILES]
C1(CC(O)=O)=CC=C(CCNS(C2=CC=C(Cl)C=C2)(=O)=O)C=C1 | [CAS DataBase Reference]
79094-20-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3
|
| Hazard Information | Back Directory | [Description]
Daltroban (BM 13505, SKF 96148), a specific thromboxane A2 receptor antagonist, was studied as an antithrombotic agent. Daltroban increases intracellular calcium in vascular smooth muscle cells. Daltroban shows a protective effect in reperfusion injury. The drug was licensed to Smith Kline Beecham and underwent phase III clinical trials in the UK and Germany as an antithrombotic agent but did not enter clinical trials in the USA. Besides, вaltroban was investigated in patients with an ischemic heart disorder. However, the development of daltroban has been discontinued.
| [Uses]
Daltroban can be used as a2 receptor to target adipose-derived stem cell for treating ischemic diseases. | [Uses]
Immunosuppressant. | [storage]
Store at -20°C |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
|