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9004-67-5

9004-67-5 Structure

9004-67-5 Structure
IdentificationBack Directory
[Name]

Methyl cellulose
[CAS]

9004-67-5
[Synonyms]

MC
nicel
viscol
tylose
sm-4000
mco8000
mellose
adulsin
bagolax
cologel
edisolm
Apolone
cethytin
mc20000s
mc4000cp
cellogel
celacolm
methocel
mmts-btr
napolone
tylosemf
tylosesl
viscosol
tylosesap
tylosetwa
tylose444
tylosea4s
FEMA 2696
syncelose
methulose
methocela
cellogran
cellothyl
celacolmm
hydrolose
cellumeth
cethylose
bulkaloid
cellapret
celacolm20
methocelmc
methocel10
methocel15
rhomellose
tylosemh20
tylosemh50
tylosesl100
tylosesl400
tylosesl600
tylosemh300
METOLOSE(R)
methocel181
methocel400
methocelchg
celacolm20p
celacolm450
culminalk42
mapolosem25
celacolmm10p
methocelmc25
methocel4000
metolosesm15
metolose60sh
METHYLCEL MC
tylosemh300p
tylosemh4000
tylosemh2000
tylosemh1000
viscontranl52
metolosesm100
methocelsm100
methocel400cps
methocelmc4000
methocelmc8000
metolosemc8000
metolosesm4000
mapolose60sh50
mapolose60shs0
METHOCEL(R) MC
cellulosemethyl
metolose60sh400
methocel4000cps
Methocel? 60 HG
Methocel? 90 HG
Methocel? 65 HG
Methoxycellulose
MethyI cellulose
bufaptomethalose
METHYLCELLULOSUM
METHYL CELLULOSE
METHOCEL(R) 90 HG
METHOCEL(R) 65 HG
METHOCEL(R) 60 HG
walsrodermc20000s
methylcellulose-a
Marpolose M 10000
Methocel? A4M
MODIFIED CELLULOSE
'TYLOSE'(R) MH 300
cellulosemethylate
uspmethylcellulose
METHYL CELLULOSE 50
METHYL CELLULOSE 25
METHYL CELLULOSE 15
MethylCellulose(Mc)
'TYLOSE'(R) MH 1000
methylcelluloseether
METHYL CELLULOSE 100
METHYL CELLULOSE 400
Methyl cellulose M20
Methylcellulose, USP
Methyl Cellulose 
Methylcellulose (AS)
Methyl cellulose,M450
Methocel? A15 LV
METHYL CELLULOSE 1500
METHYLCELLULOSE,25CPS
methylcellulose(1/2%)
MODIFIED CELLULOSE, MC
METHYL CELLULOSE 4,000
METHYL CELLULOSE NO 15
METHYL CELLULOSE (CMC)
CELLULOSE METHYL ETHER
Methyl ether cellulose
METHYL CELLULOSE NO 400
METHYL CELLULOSE NO 100
METHYLCELLULOSE, PH EUR
METHYL CELLULOSE NO 1500
METHYL CELLULOSE 400 CPS
METHYL CELLULOSE NO 4000
METHYL CELLULOSE 4000 CPS
METHYLCELLULOSE,15CPS,USP
METHYLCELLULOSE,400CPS,FCC
METHOCEL(R) MC, 10-25 MPA.S
cellulose,methylether(1/2%)
Methylcellulose (1 g) (AS)
Methylcellulose, 400 cP, FCC
Methylcellulose, 400 cP, USP
METHYLCELLULOSE,4,000CPS,FCC
METHYLCELLULOSE,4,000CPS,USP
METHYLCELLULOSE,1,500CPS,FCC
METHYLCELLULOSE, 400 CPS USP
METHYL CELLULOSE METHOCEL A4C
METHYLCELLULOSE, 1,500 CPS USP
Methylcellulose, 1,500 cP, FCC
Methylcellulose, 1,500 cP, USP
Methylcellulose, 4,000 cP, FCC
Methylcellulose, 4,000 cP, USP
CMC (PURE AND TECHNICAL GRADES)
Methylcellulose, synthesis grade
Methyl cellulose, high viscosity
METHYL CELLULOSE, VISCOSITY 15 CP
METHYL CELLULOSE, VISCOSITY 25 CP
METHYL CELLULOSE, VISCOSITY 400 CP
Methyl cellulose, middle viscosity
Methyl cellulose, viscosity 15 cPs
Methocel(R) MC, Methylcellulosum
METHYL CELLULOSE, AVERAGE MN 14,000
Methyl cellulose, viscosity 400 cPs
METHYL CELLULOSE, MEETS USP TESTING
METHYL CELLULOSE, VISCOSITY 1,500 CP
METHYL CELLULOSE, VISCOSITY 4,000 CP
Methyl cellulose, viscosity 1600 cPs
Methyl cellulose, viscosity 8000 cPs
Methyl cellulose, viscosity 4000 cPs
METHYL CELLULOSE CELL CULTURE TESTED
METHYL CELLULOSE, AVERAGE MN CA. 41,000
MethylCellulose(LowViscosity)350-550Cps
METHYL CELLULOSE, AVERAGE MN CA. 86,000
METHYL CELLULOSE, AVERAGE MN CA. 63,000
Methyl cellulose Vetec(TM) reagent grade
MethylCellulose(Mc),MethoxylContent28-32%
METHYL CELLULOSE, AVERAGE MW CA. 86,000 P
METHYL CELLULOSE, AVERAGE MW CA. 63,000 P
Methylcellulose cellulose methyl ether MC
(3,500-5,600MPa.s, 2% in Water at 20deg C)
METHYL CELLULOSE, AVERAGE MW 13,000-20,0 00
METHOCEL(R) MC, 350-500 MPA.S, LOW VIS-C OSITY
Methyl cellulose,Methocel MC, Methylcellulosum
METHOCEL(R) MC, 3000-5000 MPA.S, HIGH VI SCOSITY
METHOCEL(R) MC, 1200-1800 MPA.S, MEDIUM VISCOSITY
METHYL CELLULOSE, VISCOSITY 2% SOLN. IN WATER 25CP
Methyl Cellulose(Mc), Methoxyl Content 28-32%, Cas
Methyl Cellulose (13-18mPa.s, 2% in Water at 20deg C)
Methyl Cellulose (20-30mPa.s, 2% in Water at 20deg C)
Methyl Cellulose (80-120mPa.s, 2% in Water at 20deg C)
Methyl Cellulose (350-550mPa.s, 2% in Water at 20deg C)
Methyl cellulose, viscosity 15 cP (2% solution in water)
Methyl cellulose, viscosity 400 cP (2% solution in water)
Methyl cellulose, viscosity 4000 cP (2% solution in water)
Methyl Cellulose (1,000-1,800mPa.s, 2% in Water at 20deg C)
Methyl cellulose, viscosity (2% solution in water) 12-18 cP
Methyl Cellulose (3,500-5,600mPa.s, 2% in Water at 20deg C)
Methyl Cellulose (7,000-10,000mPa.s, 2% in Water at 20deg C)
Methyl cellulose, viscosity (2% solution in water) 3000-5600 cP
Methyl cellulose, viscosity (2% solution in water) 12-18 cP 100GR
Methyl cellulose, viscosity (2% solution in water) 3000-5600 cP 100GR
[EINECS(EC#)]

232-674-9
[Molecular Formula]

N/A
[MDL Number]

MFCD00081763
[MOL File]

9004-67-5.mol
[Molecular Weight]

454.509
Chemical PropertiesBack Directory
[Appearance]

white powder or (often) 2% solution in water, properties
[Melting point ]

290-305 °C
[density ]

1.01 g/cm3(Temp: 70 °C)
[FEMA ]

2696
[storage temp. ]

Room Temperature
[solubility ]

Practically insoluble in hot water, in acetone, in anhydrous ethanol and in toluene. It dissolves in cold water giving a colloidal solution.
[form ]

powder
[color ]

White, yellow-white or grayish-white
[Odor]

odorless
[Stability:]

Stable. Incompatible with strong oxidizing agents, bleach, perchloric acid, nitric acid, perchlorates, alkali nitrates, alkali nitrites, calcium oxide.
[Odor Type]

odorless
[Water Solubility ]

SOLUBLE IN COLD WATER
[Merck ]

14,6040
[Dielectric constant]

3.0(Ambient)
[Uses]

Methylcellulose is a gum composed of cellulose in which the meth- oxyl groups replace the hydroxyl groups. it is soluble in cold water but insoluble in hot water. solutions increase in viscosity upon heating, gel at 50–55°c, and liquefy upon cooling. it is used in baked goods for moisture retention, and in fruit pie fillings for the reduction of water absorption into the pie crust during baking. it is also used in breaded shrimp where it functions to form an oil barrier film.
[EPA Substance Registry System]

Cellulose, methyl ether(9004-67-5)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[RTECS ]

FJ5959000
[F ]

3
[TSCA ]

Yes
[HS Code ]

39129000
[Safety Profile]

A poison by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.
[Hazardous Substances Data]

9004-67-5(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Methanol-->Propylene oxide-->Chloromethane-->Defatted cotton-->COTTONSEED OIL-->alkali cellulose-->Sizy dregs
[Preparation Products]

CARRAGEENAN-->zinc oxide desulphurizer-->silver catalysts for epoxyethane-->Coating paste A
Hazard InformationBack Directory
[General Description]

Odorless white or creamy white fibrous powder. Tasteless.
[Air & Water Reactions]

Methyl cellulose is hygroscopic. Swells in water to a viscous, colloidal solid. Slightly water soluble.
[Reactivity Profile]

Methyl cellulose is incompatible with strong oxidizing agents. Methyl cellulose is also incompatible with aminacrine HCl, chlorocresol, mercuric chloride, phenol resorcinol, tannic acid and silver nitrate.
[Fire Hazard]

Flash point data for Methyl cellulose are not available; however, Methyl cellulose is probably combustible.
[Preparation]

Prepared from wood pulp or cotton by treatment with alkali and methylation of alkali cellulose with methyl chloride.
[Brand name]

Cologel (Lilly); Methocel A (Dow Chemical).
[Pharmaceutical Applications]

Methylcellulose is widely used in oral and topical pharmaceutical formulations;
In tablet formulations, low- or medium-viscosity grades of methylcellulose are used as binding agents, the methylcellulose being added either as a dry powder or in solution.Highviscosity grades of methylcellulose may also be incorporated in tablet formulations as a disintegrant.Methylcellulose may be added to a tablet formulation to produce sustained-release preparations.
Tablet cores may also be spray-coated with either aqueous or organic solutions of highly substituted low-viscosity grades of methylcellulose to mask an unpleasant taste or to modify the release of a drug by controlling the physical nature of the granules. Methylcellulose coats are also used for sealing tablet cores prior to sugar coating.
Low-viscosity grades of methylcellulose are used to emulsify olive, peanut, and mineral oils.They are also used as suspending or thickening agents for orally administered liquids, methylcellulose commonly being used in place of sugar-based syrups or other suspension bases.Methylcellulose delays the settling of suspensions and increases the contact time of drugs, such as antacids, in the stomach.
High-viscosity grades of methylcellulose are used to thicken topically applied products such as creams and gels. In ophthalmic preparations, a 0.5–1.0% w/v solution of a highly substituted, high-viscosity grade of methylcellulose has been used as a vehicle for eye drops.However, hypromellose-based formulations are now preferred for ophthalmic preparations. Methylcellulose is also used in injectable formulations.
Therapeutically, methylcellulose is used as a bulk laxative; it has also been used to aid appetite control in the management of obesity, but there is little evidence supporting its efficacy.
[Biochem/physiol Actions]

Methyl cellulose is known to have a molecular size that might pass through placenta. It is useful in visualizing small bowel loops through its overlaps.
[Safety]

Methylcellulose is widely used in a variety of oral and topical pharmaceutical formulations. It is also extensively used in cosmetics and food products, and is generally regarded as a nontoxic, nonallergenic, and nonirritant material.
Following oral consumption, methylcellulose is not digested or absorbed and is therefore a noncaloric material. Ingestion of excessive amounts of methylcellulose may temporarily increase flatulence and gastrointestinal distension.
In the normal individual, oral consumption of large amounts of methylcellulose has a laxative action and medium- or high-viscosity grades are therefore used as bulk laxatives.
Esophageal obstruction may occur if methylcellulose is swallowed with an insufficient quantity of liquid. Consumption of large quantities of methylcellulose may additionally interfere with the normal absorption of some minerals. However, this and the other adverse effects discussed above relate mainly to the use of methylcellulose as a bulk laxative and are not significant factors when methylcellulose is used as an excipient in oral preparations. Methylcellulose is not commonly used in parenteral products, although it has been used in intra-articular and intramuscular injections. Studies in rats have suggested that parenterally administered methylcellulose may cause glomerulonephritis and hypertension.Methylcellulose is considered to be toxic by the intraperitoneal route of administration.
The WHO has not specified an acceptable daily intake of methylcellulose since the level of use in foods was not considered to be a hazard to health.
LD50 (mouse, IP): 275 g/kg
[storage]

Methylcellulose powder is stable, although slightly hygroscopic. The bulk material should be stored in an airtight container in a cool, dry place.
Solutions of methylcellulose are stable to alkalis and dilute acids at pH 3–11, at room temperature. At pH less than 3, acid-catalyzed hydrolysis of the glucose–glucose linkages occurs and the viscosity of methylcellulose solutions is reduced.On heating, solution viscosity is reduced until gel formation occurs at approximately 50°C;
Methylcellulose solutions are liable to microbial spoilage and antimicrobial preservatives should therefore be used. Solutions may also be sterilized by autoclaving, although this process can decrease the viscosity of a solution.The change in viscosity after autoclaving is related to solution pH. Solutions at pH less than 4 had viscosities reduced by more than 20% subsequent to autoclaving.
[Incompatibilities]

chlorocresol; mercuric chloride; phenol; resorcinol; tannic acid; silver nitrate; cetylpyridinium chloride; p-hydroxybenzoic acid; paminobenzoic acid; methylparaben; propylparaben; and butylparaben.
Salts of mineral acids (particularly polybasic acids), phenols, and tannins will coagulate solutions of methylcellulose, although this can be prevented by the addition of ethanol (95%) or glycol diacetate. Complexation of methylcellulose occurs with highly surface-active compounds such as tetracaine and dibutoline sulfate.
High concentrations of electrolytes increase the viscosity of methylcellulose mucilages owing to the ‘salting out’ of methylcellulose. With very high concentrations of electrolytes, the methylcellulose may be completely precipitated in the form of a discrete or continuous gel. Methylcellulose is incompatible with strong oxidizing agents.
[Regulatory Status]

GRAS listed. Accepted as a food additive in the USA, Europe and Japan. Included in the FDA Inactive Ingredients Database (sublingual tablets; IM injections; intrasynovial injections; nasal preparations; ophthalmic preparations; oral capsules, oral suspensions, and oral tablets; topical and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.Reported in the EPA TSCA inventory.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Methyl cellulose(9004-67-5).msds
Questions And AnswerBack Directory
[Outline]

Methylcellulose ether, abbreviated MC, is a kind of long-chain substituted cellulose, in which 27% to 32% of the hydroxyl group exists in the form of methoxy. The substitution degree affects the physical properties of methyl cellulose such as solubility. Methylcellulose has an average molecular weight of 10,000 to 220,000. At room temperature, it exhibits as a white powder or fibrous material, and is non-toxic, non-irritating with non-allergic effect. Its apparent relative density is 0.35 to 0.55 (with the real density being 1.26 to 1.30). It swells in water into a translucent viscous colloidal solution which is neutral to litmus, insoluble in ethanol, ether and chloroform, but soluble in glacial acetic acid. It is tolerant to the effects of acid, alkali, microorganisms, heat, and light and is also not affected by oil and grease, but will burn upon reaching ignition point. Methyl cellulose is a product composed of cellulose glucose with all or part of three hydroxyls getting methylated. General products contain a methoxy fraction of 26% to 33% with degree of substitution being 1.7 to 2.2. Product with substitution degree being 1.3 to 2.6 is soluble in water, pyridine, and acetic acid. This product is widely used for architecture, such as being used as the adhesive of cement, mortar, and for mudding off the seam. It is also used for making film an adhesive in cosmetics, medicine, and food industry. It can be also used as a textile sizing agents, synthetic resin dispersing agent, paint film formers and thickeners. The production method is that: use pulp to produce the alkali cellulose; alkali cellulose is reacted with methyl chloride or dimethyl sulfate in an autoclave and then further refined with warm water to obtain the final product.
[Herbs and Applications]

Methyl cellulose is widely applied in a variety of orally administrated or topical formulations; it is also widely used in cosmetics and food. After oral administration, methyl cellulose can’t be digested or absorbed so that it is a calorie-free material. Excessive intake of methyl cellulose may temporarily increase flatulence and even cause esophageal obstruction upon insufficient water intake. However, methyl cellulose has a laxative effect.
Methyl cellulose is a hydrophilic colloid and is the high-viscosity cellulose derivatives. It is non-toxic and caustic, hygroscopic and can expand into a colloidal suspension in cold water. It is also insoluble in hot water, alcohol, ether, chloroform and saturated salt solution but is soluble in glacial acetic acid and the mixture of equal amount of alcohol and chloroform solution. Its solution may be agglomerated by salts, polybasic acid, phenol and tannin with adding ethanol being able to prevent this agglomeration effect. Methyl cellulose can’t be digested, absorbed in the intestine. It can absorb moisture, mixed with water to form a large volume of hydrophilic gum, and increase the stool volume and soften it, and also stimulate the gut peristalsis to promote the defecation. In patients with diarrhea, because the product can absorb moisture, so it reduces the intestine liquidity to take the antidiarrheal effect.
Oral administration: 1~4g/d together with taking large amounts of water as a bulk laxative for the treatment of constipation. The product has been worked as anorectic agents for controlling appetite and inducing weight loss. But it doesn’t have a reliable effect. Methyl cellulose can also be used as: adhesives which are suitable for choosing low or moderate viscosity grade plastic with both adding powder and solution working well. It is used for improving drug dissolution rate or disintegration rate; the general concentration is 1% to 2%. For gels, thickening gels and creams: it is appropriate to choose high-viscosity grade. Suspending agents and thickening agents, solutions can replace syrup; for thickening, use a concentration of up to 5%. For Tablet coating: we can choose the high-level replacement & low viscosity product as film coating; it can also be used for coating for surrounding the outer nuclear layer for isolation. For disintegrating agents, it is commonly used at a concentration of 2% to 10%. For emulsifier, it is generally recommended to use low-viscosity grade at a concentration of 1% to 5%. For eye drops, we should use high-viscosity grade.
[Stability and storage conditions]

Methyl cellulose powder is stable and slightly hygroscopic; it should be placed in an airtight container and stored in a cool dry place.
Methyl cellulose solution is sable in diluted acid or base with pH 3 to 11 at room temperature, and is easy to be destroyed by microbes to be corrupted. Therefore, the solution should be added into preservatives or subject to autoclaving. After autoclaving, the change of the solution viscosity is related with pH value. For solution of pH <4, the viscosity will decrease by more than 20% after autoclaving.
[Incompatibility]

Methylcellulose is incompatible for combination with ammonia acridine hydrochloride, chlorine cresol, mercury chloride, phenol, resorcinol, 4-aminobenzoic acid. Inorganic acid, phenol, and tannic acid cause the agglomeration of methyl cellulose; and can also forms complex with tetracaine; it can also bind with parabens so we should increase the amount of parabens upon application.
The above information is edited by the chemicalbook of Dai Xiongfeng.
[Content Analysis]

Measure the methoxy content according to the GT-14 method.
[Toxicity]

ADI does not make special provision (FAO/WHO, 2001).
GRAS (FDA, §182.1480, 2000).
[Limited application]

FAO /WHO (1984) Citrus canned; 10Mg/kg (as an anti-haze agent); cold drinks 10g/kg.
According to Japanese regulations (1990), the maximum amount is 2% (used alone or the combination amount together with calcium carboxymethyl cellulose, sodium carboxymethyl cellulose, sodium carboxymethyl starch, sodium starch phosphate).
It can also be used as the emulsion stabilizer of ice cream with the amount being 0.05%; salad sauces being 0.75%; for bread corruption prevention and surface homogenization, use 0.2% to 0.3%.
For application in citrus canned to prevent precipitation of hesperidins and the anti-clounding agent in the juice, use 10~30mg/kg.
[Chemical Properties]

It is a kind of methyl ether of cellulose. It is white or pale yellow or light gray small particles (95% through a 40 mesh sieve), filaments like or powder. It is odorless, tasteless and has hygroscopicity with an apparent density of 0.3~0.7g/mL.
When all the R in the structure is methyl, the substitution degree is equal to 3, and the methoxy content is 45.57%. For methylcellulose used as the food additive, the methoxy content should be around 26%~33% which corresponds to a degree of substitution of 1.7 to 2.2. When the substitution degree is lower than 1.3, it can be dissolved in alkaline. While methylcellulose with substitution degree higher than 2.6 is soluble in an organic solvent. When the degree of substitution is less than 1.3, it can be dissolved in alkali; for those with substitution degree higher than 2.6, it is soluble in organic solution. At the range between 1.3 and 2.6, it is soluble in cold water, pyridine, aniline, trimethyl formamide, benzyl alcohol and acetic acid.
Aqueous solution is stable at neutral and room temperature; but it can generate gelation effect and be precipitated at high temperature. Gelation temperature is dependent on the absolute viscosity and concentration of the solution; solution of large viscosity and high concentration has a relative low gelling temperature. In the presence of inorganic salts, viscosity can be increased. Due to that it belongs to a non-ionic solution, the polyvalent metal is not able to precipitate it; Gelation will only occur when the concentration of the electrolyte and other dissolved substances exceeds a certain limit.
Aqueous solution has surfactant activity and dried to form a thin film; upon heating and cooling, it will orderly go through the reversible transition from the sol to gel.
[Uses]

It can be used as thickeners; stabilizer; emulsifier; excipients; dispersant; binders; substitutes of film-forming agent hydrosol. It can also be used in mayonnaise, shortenings and some other foods. Because of that the materials can’t digested in the body, it can maintain several times amount of water, resulting in satiety; it can be used in crackers, waffles and other food for taking effect. For application, first 1/5 of the required amount of water for moistening the powder, together with cold water (necessary, to add ice) for mixing well. EEC: approved for using at frozen foam products, potato chips, soft drinks, special dietary foods, baked goods filling, the top material for foaming, sauces, and sauces.
It can also be used in mayonnaise, shortenings and some other foods.
Because of that the materials can’t digested in the body, it can maintain several times amount of water, resulting in satiety; it can be used in crackers, waffles and other food for taking effect.
For application, first 1/5 of the required amount of water for moistening the powder, together with cold water (necessary, to add ice) for mixing well. EEC: approved for using at frozen foam products, potato chips, soft drinks, special dietary foods, baked goods filling, the top material for foaming, sauces, and sauces.
The product is widely used in the architecture industry such as the mixture agent for cement, plaster, and clay seams. It can also be used as adhesive film-forming agent in cosmetics, medicine, and food industry; also can be used as sizing agents for spinning, and printing and dyeing, synthetic resin dispersing agent, paint film formers and thickeners. Methyl cellulose is a very stable material which is resistant to acid, alkalis, microorganisms, and heating. It can be excrete out from the human body without any change. It is used for synthetic resin dispersing agent, film-forming agent of painting, thickener, binder materials, textile sizing agent, and the film-forming agent in the pharmaceutical and food industries.
[Production methods]

1. Use Pulp to prepare the base fiber; then have etherification reaction to obtain methyl chloride. According to different sources, pulp can be classified into cotton pulp, wood pulp, straw pulp, etc., It is commonly used in industrial of wood pulp and cotton pulp (cotton linters). The cellulose in the pulp itself is difficult to have reaction with methyl chloride; it must first be made into alkali cellulose. Use 1 part of cellulose to be combined with 0.9-1.2 parts of sodium hydroxide and 0.9 to 1.2 parts (all by weight) of water for soak at 30 °C for 1-2h. Then compress to remove excess alkali to obtain the bulk-like alkali cellulose. Break it into pieces to loosen the alkali cellulose and make it more uniform; with the reaction with the oxygen in the air, alkaline cellulose is degraded and its polymerization is also reduced to achieve the purpose of regulating the viscosity. The alkali cellulose which has undergone the above aging process is further suspended in an excess of methyl chloride (typically 10-15 times of the weight of pulp) for taking reaction for about 5h at 60-70 °C to complete the etherification reaction with the corresponding pressure of about 1.7MPa . Post-processing of the products includes washing and drying of the finished product. Is generally washed in hot water of 80-90 °C; add an appropriate amount of hydrochloric acid (or sulfuric acid) for neutralization, and further add it into oxalic acid to make it form complex with iron and heavy metal which is removed together with sodium chloride during the washing step by water. The product was washed and dehydrated, dried to obtain methyl cellulose products.
2. Use alkali to treat wood pulp or cotton, further use methyl chloride to methylate the alkali to obtain the final product. Some industrial products contain small amounts (up to 5%) hydroxyethyl and/or cellulose displaced by hydroxypropyl. For these products, the calculation of content index should follow the percentage of methoxy group plus percentage of ethoxy group and/or percentage of propoxy with "total alkoxy" representing the content.
Spectrum DetailBack Directory
[Spectrum Detail]

Methyl cellulose(9004-67-5)IR1
Methyl cellulose(9004-67-5)Raman
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