126229-12-7
126229-12-7 结构式
基本信息
英文别名
Ccris 3484ManidipineHcl
3-(2-(4-benzhydrylpiperazin-1-yl)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate dihydrochloride
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(4-(diphenylmethyl)-1-piperazinyl)ethyl methyl ester, dihydrochloride, (+-)-
所属类别
有机原料:羧酸类化合物及衍生物应用领域
用途一
Manidipine hydrochloride is another second-generation dihydropyridine calcium
antagonist introduced as an antihypertensive. In animal studies, manidipine
hydrochloride dose-dependently decreased systolic pressure with potent and
long-lasting effects. It has little cardiodepressant activity and its claimed to be useful in hypertensive patients without the fear of cardiac failure or severe
bradycardia.