4237-93-8
中文名称
促肾上腺皮质激素-(11-24)-十四肽
英文名称
ADRENOCORTICOTROPIC HORMONE, FRAGMENT 11-24
CAS
4237-93-8
分子式
C77H134N24O16
分子量
1652.04
MOL 文件
4237-93-8.mol
更新日期
2024/05/24 13:17:50
4237-93-8 结构式
基本信息
中文别名
促肾上腺皮质激素-(11-24)-十四肽 英文别名
(11-24)-ACTHbeta11-24-ACTH
alpha11-24-ACTH
Human ACTH(11-24)
α11-24-Corticotropin
Adrenocorticotropic Hormone (11-24)
Corticotropin-(11-24)-tetradecapeptide
human adrenocorticotropic hormone (11-24)
adrenocorticotropic hormone fragment 11-24, human
ACTH (11-24) H-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
常见问题列表
生物活性
ACTH (11-24) 是促肾上腺皮质激素的多肽片段，为促肾上腺皮质激素 (ACTH) 受体拮抗剂，能够促进皮质醇的释放。靶点
Adrenocorticotropic hormone receptor
体外研究
ACTH (11-24) acts as an antagonist of adrenocorticotropic hormone receptor. ACTH (11-24) induces cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. The maximal cortisol release by ACTH (11-24) is enhanced by forskolin but inhibited by calcium channel blockers.
体内研究
ACTH (11-24) blocks electroacupuncture (EA) anti-edema but not EA anti-hyperalgesia in rats.