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464924-27-4

中文名称 H-SER-LEU-LEU-LYS-NH2
CAS 464924-27-4
分子式 C21H41N5O6
分子量 459.58
MOL 文件 464924-27-4.mol
更新日期 2024/06/11 14:26:19
464924-27-4 结构式 464924-27-4 结构式

基本信息

中文别名
SLLK,TSP1抑制剂控制肽
英文别名
SLLK
SLLK-NH2
H-SER-LEU-LEU-LYS-NH2
L-Seryl-L-leucyl-L-leucyl-L-lysine
L-Lysine, L-seryl-L-leucyl-L-leucyl-
SLLK, Control Peptide for TSP1 Inhibitor

物理化学性质

沸点815.4±65.0 °C(Predicted)
密度1.164±0.06 g/cm3(Predicted)
储存条件-15°C
酸度系数(pKa)3.31±0.10(Predicted)

常见问题列表

生物活性
SLLK, Control Peptide for TSP1 Inhibitor 是 LSKL 的对照肽。
体内研究

TGF-β1 is significantly lower (0.10±0.01 pg/mL) in the plasma of mice receiving LSKL compared with that in plasma of mice receiving SLLK control peptide at day 42 (0.20±0.02 pg/mL; P=0.0001). mRNA expression is assessed in the suprarenal aortic lysates obtained from mice receiving SLLK and LSKL peptides. Akita mice treated with 30 mg/kg LSKL have significantly increased nephrin expression, greater than twofold, compared with renal lysates from either saline controls or SLLK-treated mice.

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