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ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
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- CAS号:
- 145854-59-7
- 英文名:
- MAS 7
- 英文别名:
- MAS 7;MASTOPARAN 7;INLKALAALAKALL-NH2;Mastoparan-7, ≥97% (HPLC);MASTOPARAN 7 SYNTHETIC >98%;mastoparan from polistes jadwagae;MAS 7 - CAS 145854-59-7 - Calbiochem;Mastoparan-7 >=97% (HPLC), lyophilized powder;19: PN: WO2010069074 SEQID: 17 claimed protein;ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
- 中文名:
- ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
- 中文别名:
- 胡蜂蜂毒肽 7;黃蜂毒素MASTOPARAN 7;胡蜂蜂毒肽 7,≥97% (HPLC)
- CBNumber:
- CB0215602
- 分子式:
- C67H124N18O15
- 分子量:
- 1421.81
- MOL File:
- 145854-59-7.mol
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ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2化学性质
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沸点:
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1649.9±65.0 °C(Predicted)
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密度:
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1.154±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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形态:
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lyophilized powder
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酸度系数(pKa):
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13.43±0.46(Predicted)
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ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2性质、用途与生产工艺
Mas7 (Mastoparan 7) 是 mastoparan 的结构类似物，是异源三聚体 Gi 蛋白及其下游效应物的活化剂。
Mas7 (Mastoparan 7) produces several biological effects in different cell types. The effect of Mas7 on endogenous mono-ADP-ribosyltransferase activity is in the micromolar range with a maximal activation of 205% over the basal. In pertussis treated plasma membranes, it is found that the effect of Mas7 on endogenous mono-ADP-ribosyltransferase is partially blocked, which suggests the involvement of G-proteins, such as Gi or G0.
Mas7 is a basic tetradecapeptide isolated from isp venom, which activates guanine nucleotide-binding regulatory proteins (G-proteins) and stimulates apoptosis. In smooth muscle cells, Mas7 leads to an increase in the perfusion pressure. Vascular contraction is induced by Mas7. The vasoconstriction triggered by mas-7 exhibited a slower increase compared to that simulated by phenylephrine or vasopressin.
Exposure of hippocampal neurons to a low dose of Mas-7 increases dendritic spine density and spine head width in a time-dependent manner. Additionally, Mas-7 enhances postsynaptic density protein-95 (PSD-95) clustering in neurites and activates Gαo signaling, increasing the intracellular Ca
2+
concentration.
ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-P0258 | ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
Mas7 | 145854-59-7 | 1mg | 900元 |
| 2024/01/25 | HY-P0258 | ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
Mas7 | 145854-59-7 | 5mg | 3600元 |
ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
生产厂家
145854-59-7, ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2 相关搜索:
- Phospholipid Metabolism
- Lipids in Cell Signaling
- Phospholipase Activators
- Peptide
- G-Protein
- 药靶配体
- 多肽
- 标准品
- 细胞信号和神经生物学
- 细胞生物学
- C77H127N21O18
- C67H124N18O15
- 胡蜂蜂毒肽 7,≥97% (HPLC)
- 黃蜂毒素MASTOPARAN 7
- 胡蜂蜂毒肽 7
- 145854-59-7
- Mastoparan-7 >=97% (HPLC), lyophilized powder
- Mastoparan-7, ≥97% (HPLC)
- MAS 7 - CAS 145854-59-7 - Calbiochem
- L-Leucinamide,L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-
- mastoparan from polistes jadwagae
- MASTOPARAN 7 SYNTHETIC >98%
- MAS 7
- MASTOPARAN 7
- 19: PN: WO2010069074 SEQID: 17 claimed protein
- INLKALAALAKALL-NH2
- H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
- ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2