BIS-PEG7-NHS ESTER
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- CAS号:
- 1334170-02-3
- 英文名:
- alpha, oMega-DisucciniMidyl hexaethylene glycol
- 英文别名:
- NHS-PEG6-NHS;Di-NHS Ester-PEG7;Bis-PEG7-NHS ester;Bis-dPEG7-NHS ester;Bis-PEG7-NHS ester bis-;α,ω-disuccinimidyl hexaethylene glycol;alpha, oMega-DisucciniMidyl hexaethylene glycol;4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxo-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- 中文名:
- BIS-PEG7-NHS ESTER
- 中文别名:
- 七聚乙二醇-活性脂;双聚乙二醇7-NHS酯;双琥珀酰亚胺酯-PEG7;双-七聚乙二醇-琥珀酰亚胺酯;活性酯聚乙二醇6琥珀酰亚胺酯;琥珀酰亚胺酯-七聚乙二醇-琥珀酰亚胺酯;N-羟基琥珀酰亚胺六聚乙二醇N-羟基琥珀酰亚胺;双(2,5-二氧代吡咯烷-1-基) 4,7,10,13,16,19,22-七氧杂五烷二酸酯
- CBNumber:
- CB02546993
- 分子式:
- C26H40N2O15
- 分子量:
- 620.6
- MOL File:
- 1334170-02-3.mol
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BIS-PEG7-NHS ESTER化学性质
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溶解度:
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Soluble in DMSO, DCM, DMF
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BIS-PEG7-NHS ESTER性质、用途与生产工艺
Bis-PEG7-NHS ester 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。Bis-PEG7-NHS ester 可用于合成一系列 PROTAC 分子。Bis-PEG7-NHS ester 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
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Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
BIS-PEG7-NHS ESTER
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-126890 | BIS-PEG7-NHS ESTER
Bis-PEG7-NHS ester | 1334170-02-3 | 25 mg | 330元 |
| 2024/04/30 | HY-126890 | BIS-PEG7-NHS ESTER
Bis-PEG7-NHS ester | 1334170-02-3 | 50 mg | 520元 |
1334170-02-3, BIS-PEG7-NHS ESTER 相关搜索:
- Homobifunctional PEG
- PEG类产品-Activated molecular
- C26H40N2O15
- 双聚乙二醇7-NHS酯
- 双(2,5-二氧代吡咯烷-1-基) 4,7,10,13,16,19,22-七氧杂五烷二酸酯
- 七聚乙二醇-活性脂
- 活性酯聚乙二醇6琥珀酰亚胺酯
- 双琥珀酰亚胺酯-PEG7
- 琥珀酰亚胺酯-七聚乙二醇-琥珀酰亚胺酯
- N-羟基琥珀酰亚胺六聚乙二醇N-羟基琥珀酰亚胺
- 双-七聚乙二醇-琥珀酰亚胺酯
- 1334170-02-3
- Bis-PEG7-NHS ester bis-
- (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxo-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- Di-NHS Ester-PEG7
- Bis-dPEG7-NHS ester
- 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester
- α,ω-disuccinimidyl hexaethylene glycol
- Bis-PEG7-NHS ester
- NHS-PEG6-NHS
- alpha, oMega-DisucciniMidyl hexaethylene glycol