N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素
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- CAS号:
- 799840-96-3
- 英文名:
- Maytansinoid dM4
- 英文别名:
- Maytansinoid dM4;Maytansinoid DM4,Maytansinoid DM-4;N2'-deacetyl-n2'-(4-Mercapto-4-Methyl-1-oxopentyl)-6-MethylMaytansine;Maytansine, N2'-deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-6-methyl-
- 中文名:
- N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素
- 中文别名:
- 美坦新杂质1;化合物 T13766;英文名称:MAYTANSINOID DM4;N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素
- CBNumber:
- CB02706166
- 分子式:
- C39H56ClN3O10S
- 分子量:
- 794.4
- MOL File:
- 799840-96-3.mol
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N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素化学性质
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沸点:
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940.2±65.0 °C(Predicted)
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密度:
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1.28±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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9.83±0.70(Predicted)
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N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素性质、用途与生产工艺
Maytansinoid DM4 是一种具有强力细胞毒性的含硫醇美登素衍生物，可用作 ADC 的细胞毒性部分。
Maytansine is a natural benzoansamacrolide product isolated from the bark of the African shrub
Maytenus ovatus
. Maytansine binds to the same site on tubulin as the vinca alkaloids, with similar in vitro inhibition constants, but is a more-potent cytotoxin.
N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素
上下游产品信息
上游原料
下游产品
N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素
生产厂家
799840-96-3, N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素 相关搜索:
- 化学试剂
- 医药原料
- 原料药
- 医用原料
- 医药原料药
- C39H56ClN3O10S
- 美坦新杂质1
- 化合物 T13766
- 英文名称:MAYTANSINOID DM4
- N2'-去乙酰基-N2'-(4-巯基-4-甲基-1-氧代戊基)-6-甲基美登素
- 799840-96-3
- Maytansinoid DM4,Maytansinoid DM-4
- Maytansine, N2'-deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-6-methyl-
- N2'-deacetyl-n2'-(4-Mercapto-4-Methyl-1-oxopentyl)-6-MethylMaytansine
- Maytansinoid dM4