BIOLIMUS A9
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- CAS号:
- 851536-75-9
- 英文名:
- UMiroliMus
- 英文别名:
- TRM986;TRM 986;TRM-986;BioliMus;UMiroliMus;BIOLIMUS A9;BioliMus A9 UMiroliMus;BioliMus, BioliMus A9, TRM 986;Rapamycin, 42-O-(2-ethoxyethyl)-
- 中文名:
- BIOLIMUS A9
- 中文别名:
- 比奥利默斯;化合物 T26309;42-O-(2-乙氧基乙基)雷帕霉素
- CBNumber:
- CB22470849
- 分子式:
- C55H87NO14
- 分子量:
- 986.28
- MOL File:
- 851536-75-9.mol
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BIOLIMUS A9化学性质
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沸点:
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991.0±75.0 °C(Predicted)
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密度:
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1.15±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
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形态:
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A solid
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酸度系数(pKa):
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10.40±0.70(Predicted)
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BIOLIMUS A9性质、用途与生产工艺
Umirolimus 是一种大环三烯内酯 Rapamycin 的衍生物，是一种强大的免疫抑制剂和抗炎剂。Umirolimus 具有高度的亲脂性，可用做药物洗脱支架。
Umirolimus is a macrocyclic triene lactone, developed with pharmacological properties specifically tailored for localized drug delivery. Umirolimus can be used drug-eluting stent (DES) applications. Owing to its enhanced lipophilicity,it is strongly attracted to binding sites within the vessel wall and small, tortuous vessels, and contributing to cellular absorption and sustained distribution in the vessel wall surrounding the stent.
Umirolimus prevents progression of the cell cycle in G1 phase by inhibiting IL-2/mTOR-mediated P70-KD S6 protein kinase activation. Umirolimus inhibits T-cell growth, as well as smooth muscle cell growth.
The elimination half-life of Umirolimus is approximately 25 h in whole blood.
BIOLIMUS A9
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-122402 | Umirolimus | | 1 mg | 1363元 |
| 2024/04/30 | HY-122402 | BIOLIMUS A9
Umirolimus | 851536-75-9 | 10mg | 4800元 |
851536-75-9, BIOLIMUS A9 相关搜索:
- API
- Immunosuppressant
- 标准品
- 微生物代谢物
- C55H87NO14
- 化合物 T26309
- 比奥利默斯
- 42-O-(2-乙氧基乙基)雷帕霉素
- 851536-75-9
- TRM-986
- TRM986
- TRM 986
- BioliMus A9 UMiroliMus
- Rapamycin, 42-O-(2-ethoxyethyl)-
- UMiroliMus
- BIOLIMUS A9
- BioliMus, BioliMus A9, TRM 986
- BioliMus