AS8351
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- CAS号:
- 796-42-9
- 英文名:
- N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide
- 英文别名:
- AS8351;NSC51355;NSC-51355;NSC 51355;AS8351;AS 8351;NSC51355;NSC 51355;NSC-51355;N'-[(2-Hydroxy-1-naphthyl)methylene]isonicotinohydrazide;N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide;N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide;NSC-51355,NSC 51355,Histone Demethylase,AS8351,inhibit,Inhibitor;N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide
- 中文名:
- AS8351
- 中文别名:
- 化合物AS8351;N'-((2-羟基萘-1-基)亚甲基)吡啶-4-甲酰肼;(E)-N'-((2-羟基萘-1-基)亚甲基)异烟酰肼;N'-((2-羟基萘-1-基)亚甲基)吡啶-4-甲酰肼;PHIKAN 083,诱导成纤维细胞重编程为功能性心肌细胞
- CBNumber:
- CB23166598
- 分子式:
- C17H13N3O2
- 分子量:
- 291.3
- MOL File:
- 796-42-9.mol
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AS8351化学性质
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储存条件:
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Inert atmosphere,Store in freezer, under -20°C
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溶解度:
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Soluble in DMSO (45 mg/ml); ethanol (10 mg/ml with warming)
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形态:
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solid
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颜色:
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Yellow
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稳定性:
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Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
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AS8351性质、用途与生产工艺
AS8351 是一种 KDM5B 抑制剂，可以诱导和维持有活性的染色质标记从而促进心肌细胞样细胞的产生。
AS8351 affects epigenetic modifications by competing with α-ketoglutarate (α-KG) for chelating iron [Fe(II)] in certain epigenetic enzymes, such as the JmjC domain-containing histone demethylases (JmjC-KDMs) that require α-KG and iron as co-factors.
AS8351
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | A3339 | AS8351
AS-8351 | 796-42-9 | 10MG | 95元 |
| 2024/04/30 | A3339 | AS8351
AS-8351 | 796-42-9 | 50MG | 440元 |
AS8351
生产厂家
全球有 73家供应商
AS8351国内生产厂家
796-42-9, AS8351 相关搜索:
- API
- 药靶配体
- 肼系列
- N'-((2-羟基萘-1-基)亚甲基)吡啶-4-甲酰肼
- PHIKAN 083,诱导成纤维细胞重编程为功能性心肌细胞
- N'-((2-羟基萘-1-基)亚甲基)吡啶-4-甲酰肼
- (E)-N'-((2-羟基萘-1-基)亚甲基)异烟酰肼
- 化合物AS8351
- 796-42-9
- N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide
- NSC-51355,NSC 51355,Histone Demethylase,AS8351,inhibit,Inhibitor
- N'-[(2-Hydroxy-1-naphthyl)methylene]isonicotinohydrazide
- 4-Pyridinecarboxylic acid, 2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
- N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide
- N'-[(2-hydroxynaphthalen-1-yl)methylidene]pyridine-4-carbohydrazide
- NSC51355
- NSC 51355
- AS8351;AS 8351;NSC51355;NSC 51355;NSC-51355
- NSC-51355
- N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide
- AS8351