D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
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- CAS号:
- 51555-87-4
- 英文名:
- THIODIGALACTOSIDE
- 英文别名:
- TDG;THIODIGALACTOSIDE;Galactosyl 1-thiogalactoside;D-Galactopyranosyl-β-D-thiogalactopyranoside;D-Galactopyranosyl-b-D-thiogalactopyranoside;d-galactopyranosyl-β-d-thiogalactopyranoside;D-GALACTOPYRANOSYL BETA-D-THIOGALACTOPYRANOSIDE;D-Galactopyranosyl-β-D-thiogalactopyranoside ,98%;β-D-Galactopyranoside, β-D-galactopyranosyl 1-thio-
- 中文名:
- D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
- 中文别名:
- 硫代半乳糖苷;N4苯甲酰基5'-O-DMT-5-甲基;D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷;D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷;(D-GALACTOPYRANOSYL)-B-D-THIOGALACTOPYRANOSIDE 硫代二半乳糖苷
- CBNumber:
- CB2340922
- 分子式:
- C12H22O10S
- 分子量:
- 358.36
- MOL File:
- 51555-87-4.mol
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D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷化学性质
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熔点:
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>225°C (dec.)
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储存条件:
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−20°C
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溶解度:
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DMSO (Slightly)
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形态:
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Solid
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颜色:
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White
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D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷性质、用途与生产工艺
Thiodigalactoside (TDG) 是一种具有口服活性的，有效的半乳凝素 (GAL) 抑制剂，对于 GAL-1 和 GAL-3 的 Kd 值分别为 24 μM，49 μM。Thiodigalactoside 是一种不可代谢的二糖，具有抗炎和抗癌活性。Thiodigalactoside 可显着降低饮食诱发的肥胖大鼠的体重增加。
Kd: 24 μM (GAL1) and 49 μM (GAL3)
Thiodigalactoside (TDG; 250 and 500 μM) exhibits dose-dependent reduction of fat accumulation based on triglyceride (TG) content and Oil Red O (ORO) staining.
Thiodigalactoside (TDG; 5 mg/kg; IP; once per week for 5 weeks) results in dramatic inhibition of HFD-induced body weight gain.
Thiodigalactoside (5 mg/kg; oral; daily or weekly for 5 weeks) gave less reduction in body weight gain compare with i.p..
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Animal Model:
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Five-week-old Sprague-Dawley (SD) male rats
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Dosage:
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5 mg/kg
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Administration:
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IP; once per week for 5 weeks
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Result:
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Resulted in dramatic inhibition of HFD-induced body weight gain by inhibiting adipogenesis and lipogensis as well as by increasing expression of the proteins associated with thermogenesis and energy expenditure.
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D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-130208 | Thiodigalactoside | | 10 mg | 380元 |
| 2024/01/25 | HY-130208 | D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
Thiodigalactoside | 51555-87-4 | 25mg | 560元 |
D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
生产厂家
51555-87-4, D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷 相关搜索:
- 生化试剂
- Disaccharide
- BioChemical
- Biochemicals and Reagents
- Carbohydrates
- D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
- N4苯甲酰基5'-O-DMT-5-甲基
- (D-GALACTOPYRANOSYL)-B-D-THIOGALACTOPYRANOSIDE 硫代二半乳糖苷
- 硫代半乳糖苷
- D-吡喃半乳糖 Β-D-硫代吡喃半乳糖苷
- 51555-87-4
- D-Galactopyranosyl-β-D-thiogalactopyranoside
- β-D-Galactopyranoside, β-D-galactopyranosyl 1-thio-
- TDG
- Galactosyl 1-thiogalactoside
- THIODIGALACTOSIDE
- D-Galactopyranosyl-β-D-thiogalactopyranoside ,98%
- D-Galactopyranosyl-b-D-thiogalactopyranoside
- d-galactopyranosyl-β-d-thiogalactopyranoside
- D-GALACTOPYRANOSYL BETA-D-THIOGALACTOPYRANOSIDE