Boc-Val-Cit-PABA
|
|
|
- CAS号:
- 870487-09-5
- 英文名:
- Boc-Val-Cit-PABA
- 英文别名:
- Boc-Gly-Gly-Phe-Gly;Boc-Val-Cit-PAB-OH;tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;Boc-Val-Cit-PABA;Pentanoicacid,2,6-dioxo-,methylester;Inhibitor,inhibit,ADC Linkers,Boc Val Cit PAB,BocValCitPAB,Antibody-drug conjugates linkers;(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide;N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide;L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
- 中文名:
- Boc-Val-Cit-PABA
- 中文别名:
- 化合物BOC-VAL-CIT-PAB;(S)-2-[(S)-2-(BOC-氨基)-3-甲基丁酰氨基]-N-[4-(羟甲基)苯基]-5-脲基戊酰胺;3-甲基-1-氧代丁基-1-(4-羟甲基苯基)氨基-1-氧代-5-脲基戊烷氨基)-3-甲基-1-氧代丁烷-2-氨基甲酸酯;((S)-1-(((S)-1-((4-(羟甲基)苯基)氨基)-1-氧代-5-脲基戊-2-基)氨基)-3-甲基-1-氧代丁-2-基)氨基甲酸叔丁酯
- CBNumber:
- CB43059339
- 分子式:
- C23H37N5O6
- 分子量:
- 479.57
- MOL File:
- 870487-09-5.mol
|
|
|
Boc-Val-Cit-PABA化学性质
-
沸点:
-
771.3±60.0 °C(Predicted)
-
|
-
密度:
-
1.209±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
DMSO : 100 mg/mL (208.52 mM; Need ultrasonic)
-
|
-
酸度系数(pKa):
-
11.25±0.46(Predicted)
-
|
Boc-Val-Cit-PABA性质、用途与生产工艺
Boc-Val-Cit-PAB是可裂解的ADC接头，用于抗体-药物偶联物（ADC）的合成。
ADC由抗体组成，通过ADC接头将ADC细胞毒素与抗体结合。
Boc-Val-Cit-PAB 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Boc-Val-Cit-PABA
上下游产品信息
上游原料
下游产品
870487-09-5, Boc-Val-Cit-PABA 相关搜索:
- ADCs
- ADC LINKER
- Linker
- 化学试剂
- 生物化学品
- 生物试剂
- C23H37N5O6
- 3-甲基-1-氧代丁基-1-(4-羟甲基苯基)氨基-1-氧代-5-脲基戊烷氨基)-3-甲基-1-氧代丁烷-2-氨基甲酸酯
- ((S)-1-(((S)-1-((4-(羟甲基)苯基)氨基)-1-氧代-5-脲基戊-2-基)氨基)-3-甲基-1-氧代丁-2-基)氨基甲酸叔丁酯
- 化合物BOC-VAL-CIT-PAB
- (S)-2-[(S)-2-(BOC-氨基)-3-甲基丁酰氨基]-N-[4-(羟甲基)苯基]-5-脲基戊酰胺
- 870487-09-5
- Inhibitor,inhibit,ADC Linkers,Boc Val Cit PAB,BocValCitPAB,Antibody-drug conjugates linkers
- Pentanoicacid,2,6-dioxo-,methylester
- Boc-Val-Cit-PAB-OH
- Boc-Gly-Gly-Phe-Gly
- tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
- L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
- (S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide
- N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
- Boc-Val-Cit-PABA