VL285
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- CAS号:
- 1448188-57-5
- 英文名:
- VL285
- 英文别名:
- VL285;VL-285; VL 285; VL285;E3 ligase-recruiting Moiety,VL-285,Ligands for E3 Ligase,Inhibitor,inhibit,VL285,VL 285;(2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, 1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-
- 中文名:
- VL285
- 中文别名:
- 化合物VL285;(2S,4R)-4-羟基-1-((S)-3-甲基-2-(1-氧代异吲哚啉-2-基)丁酰基)-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷-2-甲酰胺
- CBNumber:
- CB44812456
- 分子式:
- C29H32N4O4S
- 分子量:
- 532.65
- MOL File:
- 1448188-57-5.mol
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VL285化学性质
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储存条件:
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Sealed in dry,Store in freezer, under -20°C
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VL285性质、用途与生产工艺
VL285 是一种有效的 VHL ligand ，可降解HaloTag7融合蛋白。VL285是HaloPROTAC3的核心VHL配体，与过量的VL285共处理能够显著地降低HaloPROTAC3介导的降解活性至50%。
VL285
上下游产品信息
上游原料
下游产品
1448188-57-5, VL285 相关搜索:
- 药靶配体
- (2S,4R)-4-羟基-1-((S)-3-甲基-2-(1-氧代异吲哚啉-2-基)丁酰基)-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷-2-甲酰胺
- 化合物VL285
- 1448188-57-5
- E3 ligase-recruiting Moiety,VL-285,Ligands for E3 Ligase,Inhibitor,inhibit,VL285,VL 285
- (2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
- (2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide
- 2-Pyrrolidinecarboxamide, 1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-
- VL-285; VL 285; VL285
- VL285