Trehalose 6-behenate
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- CAS号:
- 66755-19-9
- 英文名:
- Trehalose 6-behenate
- 英文别名:
- Trehalose 6-behete;Trehalose 6-behenate;Trehalose 6behenate,Trehalose 6 behenate;α-D-Glucopyranoside, α-D-glucopyranosyl, 6-docosanoate (9CI)
- 中文名:
- Trehalose 6-behenate
- 中文别名:
- 化合物 T19590;海藻糖 6-山嵛酸酯
- CBNumber:
- CB88054867
- 分子式:
- C34H64O12
- 分子量:
- 664.86
- MOL File:
- 66755-19-9.mol
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Trehalose 6-behenate化学性质
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沸点:
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784.1±60.0 °C(Predicted)
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密度:
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1.20±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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12.75±0.70(Predicted)
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Trehalose 6-behenate性质、用途与生产工艺
Trehalose 6-behenate 是一种 Th1/Th17 疫苗佐剂。
Trehalose 6-behenate (TDB) exerts its effect through binding to the macrophage-inducible C-type lectin Mincle, a pathogen recognition receptor (PRR) that recognises pathogen-associated molecular patterns (PAMPs). The potential of Th1/Th17 skewing adjuvants in vaccine development provides a very real incentive for better definition of the structural motifs required for Mincle binding. Mincle is highly conserved between mice and humans, with 85 % protein similarity. In addition to being a receptor for TDMs, Trehalose 6-behenate (TDB), and the spliceosome-associated protein (SAP)130 (which activates Mincle at a binding site different to that involved in carbohydrate recognition), Mincle is also a receptor for
Candida albicans
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Malassezia
, and
Fonsecaea pedrosoi
.
Trehalose 6-behenate
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Trehalose 6-behenate
生产厂家
66755-19-9, Trehalose 6-behenate 相关搜索:
- 化合物 T19590
- 海藻糖 6-山嵛酸酯
- 66755-19-9
- α-D-Glucopyranoside, α-D-glucopyranosyl, 6-docosanoate (9CI)
- Trehalose 6behenate,Trehalose 6 behenate
- Trehalose 6-behete
- Trehalose 6-behenate