10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin

Thioridazine Struktur
50-52-2
CAS-Nr.
50-52-2
Bezeichnung:
10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin
Englisch Name:
Thioridazine
Synonyma:
tp21;TP-21;Thioril;Meleril;Sonapax;Mallorol;Malloryl;Mellaril;Mellarit;Melleril
CBNumber:
CB6763367
Summenformel:
C21H26N2S2
Molgewicht:
370.57
MOL-Datei:
50-52-2.mol

10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Eigenschaften

Schmelzpunkt:
72-74°
Siedepunkt:
bp0.02 230°
Dichte
1.1693 (rough estimate)
Brechungsindex
1.5800 (estimate)
Flammpunkt:
9℃
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
Practically insoluble in water, very soluble in methylene chloride, freely soluble in methanol, soluble in ethanol (96 per cent).
pka
9.5(at 25℃)
Wasserlöslichkeit
1.113mg/L(22.5 ºC)
NIST chemische Informationen
10H-Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-(50-52-2)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher F,T
R-Sätze: 11-23/24/25-39/23/24/25-52/53
S-Sätze: 16-36/37-45-61
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
HS Code  2934302300
Giftige Stoffe Daten 50-52-2(Hazardous Substances Data)
Toxizität LD50 orally in rats: 995 ±39 mg/kg (Goldenthal)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

An antipsychotic drug of the phenothiazine class. It is of particular interest because of its “atypical” properties, some of which may be due to its extensive bioconversion to active metabolites. The therapeutic and side effects of thioridazine and its metabolites involve blockade of brain dopamine receptors, but also actions mediated via blockage of muscarininc cholinergic and α-adrenergic receptors.

Chemische Eigenschaften

Colorless crystals. Soluble in water and alcohol.

Verwenden

In terms of antipsychotic activity, thioridazine is inferior to aminazine. It is most effective in mental and emotional disorders accompanied by fear, stress, and excitement. It is prescribed for various forms of schizophrenia, psychosis, and neurosis.

Definition

ChEBI: A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 70)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
bruce@xrdchem.cn CHINA 566 55
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2931 58
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86-13657291602
linda@hubeijusheng.com CHINA 22968 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674;
factory@coreychem.com China 29826 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 29271 58
AFINE CHEMICALS LIMITED
0571-85134551
info@afinechem.com CHINA 15377 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com CHINA 52867 58
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GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49999 58

50-52-2(10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin)Verwandte Suche:


  • THIORIDAZINE
  • 10-[2-(1-Methyl-2-piperidyl)]-2-[methylthio] phenothiazine
  • THIORIDAZINE,1.0MG/MLINMETHANOL
  • 10-[2-(1-ethyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine
  • 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)- (9CI)
  • dl-Thioridazine
  • Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- (6CI, 8CI)
  • Thioril
  • 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
  • 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanyl-phenothiazine
  • THIORIDAZINE BASE
  • Thioridazine (200 mg)
  • 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin
  • 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazin
  • 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin
  • 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine
  • 10-[2-(1-Methyl-2-piperdiyl)ethyl]-2-(methylthio)phenothiazine
  • 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine
  • 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-
  • 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine
  • 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-10h-phenothiazine
  • Thioridazine solution
  • 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine
  • 10-(2-(1-Methylpiperidin-2-yl)
  • 2-methylmercapto-10-(2-n-methyl-2-piperidyl)ethyl)phenothiazine
  • 3-methylmercapto-n-[2’-(n-methyl-2-piperidyl)ethyl]phenothiazine
  • Mallorol
  • Malloryl
  • Meleril
  • Mellaril
  • Mellaril-S
  • Mellarit
  • Mellerets
  • Mellerette
  • Melleretten
  • Melleril
  • melleril(liquid)
  • Phenothiazine, 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-
  • Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-
  • Sonapax
  • Thioridazin
  • Thioridazine, prolongatum
  • thioridazineprolongatum
  • tp21
  • TP-21
  • Thioridazine CRS
  • Thioridazine for system suitability CRS
  • Thioridazine USP/EP/BP
  • Thioridazine DISCONTINUED. Please see T368800.
  • Thioridazine (1662504)
  • hioridazine
  • 50-52-2
  • C21H26N2S2
  • Thioridazine
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