Hydrogenbromid Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSES KOMPRIMIERTES FLüSSIGGAS MIT STECHENDEM GERUCH.
PHYSIKALISCHE GEFAHREN
Das Gas ist schwerer als Luft.
CHEMISCHE GEFAHREN
Starke Säure in wässriger Lösung. Reagiert sehr heftig mit Basen. ätzend. Reagiert sehr heftig mit starken Oxidationsmittelnund vielen organischen Stoffen unter Feuer- und Explosionsgefahr. Greift viele Metalle unter Bildung brennbarer/explosionsfähiger Gase an (z.B. Wasserstoff, ICSC-Nr. 0001).
ARBEITSPLATZGRENZWERTE
TLV: 2 ppm (als STEL, ceiling); (ACGIH 2005).
MAK: 2 ppm, 6.7 mg/m? Spitzenbegrenzung: überschreitungsfaktor I(1); Schwangerschaft: Gruppe D (DFG 2006).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation.
INHALATIONSGEFAHREN
Eine gesundheitsschädliche Konzentration des Gases in der Luft wird beim Entweichen aus dem Behälter sehr schnell erreicht.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz verätzt die Augen, die Haut und die Atemwege. Inhalation des Gases kann zu Lungenödem führen (s. Anm.). Schnelle Verdampfung kann zu Erfrierungen führen.
LECKAGE
Gefahrenbereich verlassen! Fachmann zu Rate ziehen! Belüftung. Wasserstrahl NIEMALS auf die Flüssigkeit richten. Gas mit feinem Wassersprühstrahl niederschlagen. Gasdichter Chemikalienschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät.
R-Sätze Betriebsanweisung:
R35:Verursacht schwere Verätzungen.
R37:Reizt die Atmungsorgane.
R34:Verursacht Verätzungen.
R10:Entzündlich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S7/9:Behälter dicht geschlossen an einem gut gelüfteten Ort aufbewahren.
Aussehen Eigenschaften
HBr; gelbliche, stechend riechende Flüssigkeit.
Gefahren für Mensch und Umwelt
Bromwasserstoffsäure färbt sich bei Zutritt von Licht und Luft allmählich braun. Die konzentrierte Säure wird durch Oxidationsmittel wie Wasserstoffperoxid, Salpetersäure oder konz. Schwefelsäure zu Brom oxidiert. Eisen, Nickel, Zinn, Aluminium, Mangan, Silicium, u.a. lösen sich in HBr unter Wasserstoffentwicklung (Explosionsgefahr!) zu Bromiden. Bei Kontakt mit konz. Laugen sind heftige Reaktionen möglich.
Bromwasserstoffsäure wirkt stark ätzend auf Augen, Haut und Schleimhäute. Dämpfe können zu entzündlichen Reizungen oder Schädigungen der Atemwege, Schleimhäute und Augen führen. Inhalation kann infolge von Lähmung, Entzündung und Ödem von Kehlkopf und Lunge zum Tode führen.
Schwach wassergefährdender Stoff.
Schutzmaßnahmen und Verhaltensregeln
Im Abzug arbeiten.
Handschuhe aus Gummi (nur als kurzzeitiger Spritzschutz)
Verhalten im Gefahrfall
Bei Verschütten für ausreichende Belüftung sorgen. Mit flüssigkeitsbindendem Material (z.B. Sand, Kieselgur, Chemisorb) aufnehmen. Kleinere Mengen mit Kalkmilch neutralisieren und mit viel Wasser verdünnen. Austretende Gase/Dämpfe mit Wasser niederschlagen.
Wasser, Schaum (Bromwasserstoffsäure selbst ist nicht brennbar).
Erste Hilfe
Nach Hautkontakt: Sofort mit viel Wasser abwaschen. Abtupfen mit Polyethylenglykol 400.
Nach Augenkontakt: Gründlich bei geöffnetem Lid mindestens 15 Minuten mit viel Wasser spülen. Augenarzt konsultieren.
Nach Einatmen: Frischluft. Arzt hinzuziehen.
Nach Verschlucken: Viel Wasser trinken lassen. Erbrechen vermeiden (Perforationsgefahr). Sofort Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung sofort ausziehen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Kleinere Mengen vorsichtig unter starkem Rühren mit Überschuß an Wasser neutralisieren. Wasserunlösliche Bestandteile werden nach Abtrennen als halogenhaltiger Sondermüll entsorgt. Die wässrige Phase wird nach Verdünnen im Abguß verworfen.
Größere Mengen als Sondermüll entsorgem.
Beschreibung
Hydrobromic Acid is a strong acid formed by dissolving the
diatomic molecule HBr in water. “Constant-boiling”
hydrobromic acid is an aqueous solution that distills at
124.3°C and contains 47.6% HBr by weight. Hydrobromic
acid has a pKa of 9, making it a stronger acid
than hydrochloric acid, but not as strong as HI, hydroiodic
acid. Hydrobromic acid is one of the strongest
mineral acids known.
Hydrobromic acid is mainly used for the production
of inorganic bromides, especially the bromides of zinc,
calcium, and sodium. It is a useful reagent for generating
organobromine compounds. Certain ethers are
cleaved with HBr. It also catalyzes alkylation reactions
and the extraction of certain ores. Industrially significant
organic compounds prepared from hydrobromic
acid include allyl bromide, tetrabromobis(phenol),
and bromoacetic acid.
Hydrobromic acid can be prepared in the laboratory
via the reaction of Br2, SO2 and water. Another laboratory
preparation involves the production of anhydrous
HBr, which is then dissolved in water.
Hydrobromic acid has commonly been prepared
industrially by reacting bromine with either sulfur or
phosphorous and water. However, it can also be
produced electrolytically. It can also be prepared by
treating bromides with nonoxidizing acids like phosphoric
or acetic acids. Hydrobromic acid is available
commercially in various concentrations and purities.
Chemische Eigenschaften
colourless liquid with a strong irritating odour
Physikalische Eigenschaften
Colorless gas; fumes in moist air; pungent acrid odor; nonflammable; heav-ier than air; density 2.71 (air=1.0); gas density 3.55 g/L at 25°C; liquefies at-66.4°C; solidifies at -86.8°C; critical temperature 89.8°C; critical pressure84.5 atm; highly soluble in water (saturated aqueous solution contains 66%HBr at 25°C); forms a constant-boiling azeotrope at 47.5% HBr in solution,boiling at 126°C at atmospheric pressure; soluble in alcohol; a 0.10Maqueoussolution is 93% ionized to H+and Br ? ions at 18°C.
Verwenden
Hydrogen bromide is used as a reagent and
catalyst in several types of organic reactions
such as the formation of alkyl bromides from
alcohols.
It is also used as a source material in the
preparation of inorganic bromides. Hydrogen
bromide serves as a catalyst in alkylation reactions.
It has also been reportedly used in the
controlled oxidation of aliphatic and alicyclic
hydrocarbons to peroxides, ketones, and acids.
In organic synthesis, hydrogen bromide is used
to substitute bromine for aliphatic chlorine in
the presence of aluminum catalyst.
Definition
Hydrogen bromide in aqueous solution.
synthetische
Hydrogen bromide gas may be produced by combustion of hydrogen inbromine vapor at 37.5°C using a catalyst such as platinized asbestos or pla-tinized silica gel. Unreacted free bromine is removed from the product bypassing the gaseous product mixture over hot activated charcoal. Hydrogenbromide formed may be absorbed in water to obtain the acid; or may be cooledand liquefied for shipment in cylinders.
Hydrobromic acid may be prepared in the laboratory by distillation of asolution of potassium bromide with dilute sulfuric acid:
2KBr + H
2SO
4 → K
2SO
4 + HBr
The acid may be prepared by several other methods, as well, including reac-tion of bromine either with sulfur and water; or with phosphorus and water:
2Br
2 + S + 2H
2O → 4HBr + SO
2
Hydrobromic acid also may be prepared by hydrogen exchange with a sodiumor potassium bromide solution when the solution is passed through a cation-exchange resin.
Hydrobromic acid is stored and shipped in drums, tanks, carboys, or bot-tles, labeled as corrosive materials. The anhydrous gas is stored and shippedin cylinders under its vapor pressure.
Allgemeine Beschreibung
Hydrobromic acid solution (HBr) is a clear, yellow or brown colored liquid. Its reaction with K has been studied by a molecular beam technique.
Air & Water Reaktionen
Acrid odor, fumes in moist air forming clouds containing hydrobromic acid. Heat of solution large, [Merck, 11th ed., 1989].
Reaktivität anzeigen
HYDROGEN BROMIDE is an anhydrous (no water) strong acid. Reacts rapidly and exothermically with bases of all kinds (including amines and amides). Reacts exothermically with carbonates (including limestone and building materials containing limestone) and hydrogen carbonates to generate carbon dioxide. Reacts with sulfides, carbides, borides, and phosphides to generate toxic or flammable gases. Reacts with many metals (including aluminum, zinc, calcium, magnesium, iron, tin and all of the alkali metals) to generate flammable hydrogen gas. Reacts violently with acetic anhydride, 2-aminoethanol, ammonium hydroxide, calcium phosphide, chlorosulfonic acid, 1,1-difluoroethylene, ethylenediamine, ethyleneimine, oleum, perchloric acid, b-propiolactone, propylene oxide, silver perchlorate/carbon tetrachloride mixture, sodium hydroxide, uranium(IV) phosphide, vinyl acetate, calcium carbide, rubidium carbide, cesium acetylide, rubidium acetylide, magnesium boride, mercury(II) sulfate, calcium phosphide, calcium carbide.
Hazard
Toxic by inhalation, strong irritant to eyes
and skin.
Health Hazard
Hydrobromic acid and hydrogen bromide gas are highly corrosive substances that
can cause severe burns upon contact with all body tissues. The aqueous acid and gas
are strong eye irritants and lacrimators. Contact of concentrated hydrobromic acid or
concentrated HBr vapor with the eyes may cause severe injury, resulting in
permanent impairment of vision and possible blindness. Skin contact with the acid
or HBr gas can produce severe burns. Ingestion can lead to severe burns of the
mouth, throat, and gastrointestinal system and can be fatal. Inhalation of hydrogen
bromide gas can cause extreme irritation and injury to the upper respiratory tract and
lungs, and exposure to high concentrations may cause death. HBr gas is regarded as
having adequate warning properties.
Hydrogen bromide has not been found to be carcinogenic or to show reproductive or
developmental toxicity in humans.
Brandgefahr
Behavior in Fire: Pressurized container may explode and release toxic, irritating vapor.
Flammability and Explosibility
Noncombustible, but contact with metals may produce highly flammable hydrogen
gas.
Materials Uses
Hydrogen bromide does not aggressively attack
common metals of construction while in the
anhydrous state. However, in the presence of
moisture, hydrogen bromide will attack most
metals except platinum and silver. Galvanized
pipe, brass, and bronze should be avoided.
Steel, Monel, and aluminum-silicon-bronze
have proven satisfactory in anhydrous hydrogen
bromide service.
Lager
Splash goggles and rubber gloves should be
worn when handling this acid, and containers of HBr should be stored in a wellventilated
location separated from incompatible metals. Water should never be
added to HBr because splattering may result; always add acid to water. Containers of
hydrobromic acid should be stored in secondary plastic trays to avoid corrosion of
metal storage shelves due to drips or spills.
Cylinders of hydrogen bromide
should be stored in cool, dry locations, separated from alkali metals and other
incompatible substances.
läuterung methode
A solution of aqueous HBr ca 48% (w/w, constant boiling) is purified by distilling twice with a little red phosphorus, and the middle half of the distillate is taken. (The azeotrope at 760mm contains 47.8% (w/w) HBr.) [Hetzer et al. J Phys Chem 66 1423 1962]. Free bromine can be removed by Irvine and Wilson's method for HI (see above), except that the column is regenerated by washing with an ethanolic solution of aniline or styrene. Hydrobromic acid can also be purified by aerating with H2S, distilling and collecting the fraction boiling at 125-127o. [Heisig & Andur Inorg Synth I 155 1939.] HARMFUL VAPOURS.
Inkompatibilitäten
Hydrobromic acid and hydrogen bromide react violently with many metals with the
generation of highly flammable hydrogen gas, which may explode. Reaction with
oxidizers such as permanganates, chlorates, chlorites, and hypochlorites may
produce chlorine or bromine.
Waste disposal
In many localities, hydrobromic acid or the residue from a spill may be disposed of down the drain after
appropriate dilution and neutralization. Otherwise, hydrobromic acid and waste material containing this
substance should be placed in an appropriate container, clearly labeled, and handled according to your
institution's waste disposal guidelines. Excess hydrogen bromide in cylinders should be returned to the
manufacturer. For more information on disposal procedures, see Chapter 7 of this volume.
Hydrogenbromid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
8-Bromtheophyllin
2-(DIBROMOACETYL BENZIMIDAZOLE HYDRO BROMIC ACID SALT
METHYL 2-AMINO-2-(4-HYDROXYPHENYL)ACETATE
4-Bromopiperidine hydrobromide
8-Bromooctanoic acid
2-Methoxy-6-methylbenzoic acid
4,4'-Bis(bromomethyl)biphenyl
3,8-DIMETHYL-1,10-PHENANTHROLINE
Cyclohexylammoniumbromid
2-MERCAPTOPYRIMIDIN-4-OL
1,10-Dibromdecan
4-Brom-o-xylol
2-BROMO-1-(4,6-DIMETHOXYPYRIMIDIN-2-YL)ETHANONE
9-Bromo-9-phenylfluorene
10-METHYLSULFONYL)CAPRIC ACID
5-Methylpyridine-3-boronic acid
3-(Bromacetyl)pyridiniumbromid
2,6-DIAMINO-3-BROMOPYRIDINE
4-BROMO-7-CHLOROQUINOLINE
10-Bromodecanoic acid
3-Fursaeure
8-Bromoctan-1-ol
1,1,3,3-TETRABROMOACETONE
Brombernsteinsure
1-Methylpiperidin-3-ol
4-(Bromoacetyl)pyridine hydrobromide
5-Bromthiazol-2-aminmonohydrobromid
4-Bromo-2,3,5,6-tetrafluoropyridine
α-Brom-p-xylol
2-ACETYLAMINO-3-BROMO-5-METHYLPYRIDINE
(2-FLUOROBENZYL)METHYLAMINE
3-Bromo-2,6-diaminopyridine ,95%
4-Brom-1,2-difluorbenzol
2-Bromo-3-methoxy-6-methylpyridine
2-Bromo-3-hydroxy-6-methylpyridine
4-TRIFLUOROMETHYLBENZYLSULFONYL CHLORIDE
Zinkbromid
1-Hydroxybutan-2-on
S-2-Aminoethylthiouroniumbromidhydrobromid
1-Hexanthiol
