Naled (ISO) Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE BIS GELBE FLüSSIGKEIT ODER WEISSE KRISTALLE MIT STECHENDEM GERUCH.
CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen, bei Kontakt mit Säurenund Oxidationsmitteln unter Bildung giftiger und ätzender Rauche mit Bromwasserstoff, Chlorwasserstoffund Phosphoroxiden. Zersetzung bei Kontakt mit Wasser unter Bildung von Dichlorvos und Dichloracetaldehyd. Greift Metall, Kunststoff, Gummi und Beschichtungen an.
ARBEITSPLATZGRENZWERTE
TLV: (Einatembare Fraktion) 0.1 mg/m?(als TWA); Hautresorption; Krebskategorie A4 (nicht klassifizierbar als krebserzeugend für den Menschen); Sensibilisierung; BEI vorhanden; (ACGIH 2005).
MAK: 1 mg/m?(Einatembare Fraktion); Spitzenbegrenzung: überschreitungsfaktor II(2); Hautresorption; Sensibilisierung der Haut; Schwangerschaft: Gruppe C; (DFG 2008).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation des Aerosols, über die Haut und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt eine gesundheitsschädliche Kontamination der Luft nicht oder nur sehr langsam ein; viel schneller jedoch beim Versprühen oder Dispergieren.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atemwege. Möglich sind Auswirkungen auf das Nervensystem mit nachfolgenden Krämpfen und Atemdepression. Cholinesterasehemmer. Exposition weit oberhalb der Arbeitsplatzgrenzwerte kann zum Tod führen. Die Auswirkungen treten u.U. verzögert ein. ärztliche Beobachtung notwendig.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Cholinesterasehemmer. Kumulative Wirkung möglich (s. AKUTE GEFAHREN/SYMPTOME).
LECKAGE
Persönliche Schutzausrüstung: Chemikalienschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät. NICHT in die Umwelt gelangen lassen. Verschüttetes Material in abdichtbaren Behältern sammeln. Reste sorgfältig sammeln. An sicheren Ort bringen. Bei Flüssigkeiten: Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen.
R-Sätze Betriebsanweisung:
R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
R36/38:Reizt die Augen und die Haut.
R50:Sehr giftig für Wasserorganismen.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Sensitization to Naled seems to be rare.
Chemische Eigenschaften
Naled is a white crystalline solid (when pure)
or light straw-colored liquid (above 26.7℃) with a slightly
pungent insecticide odor.
Physikalische Eigenschaften
Colorless to pale yellow liquid or solid with a pungent odor
Verwenden
Naled is used to control mites, sucking pests and some other
insects in a wide variety of crops. It is also used for the control of public
and animal health pests including mosquitoes.
Definition
ChEBI: An dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use wit
in the European Union.
Allgemeine Beschreibung
DIBROM is a white solid that may be dissolved in a liquid organic carrier with a pungent odor. DIBROM is a water emulsifiable liquid. DIBROM is insoluble in water and sinks in water. DIBROM can cause illness by inhalation, skin absorption and/or ingestion. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. If DIBROM is in liquid form, DIBROM can easily penetrate the soil and contaminate groundwater and nearby streams. DIBROM is used as a pesticide.
Air & Water Reaktionen
Practically insoluble in water [Farm Chemicals Handbook]. Hydrolyzed slowly in presence of water.
Reaktivität anzeigen
DIBROM is incompatible with the following: Strong oxidizers, acids, sunlight, water [Note: Corrosive to metals. Hydrolyzed in presence of water.] . Unstable in presence of Iron [USCG, 1999]. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Hazard
Technical compound is a moderately volatile liquid. Bp 110C (0.5 mm Hg). Insoluble in water;
slightly soluble in aliphatic solvents; very soluble
in aromatic solvents; hydrolyzes in water.
Health Hazard
INHALATION OR INGESTION: Symptoms secondary to cholinesterase inhibition are: headache, giddiness, nervousness, blurred vision, weakness, nausea, cramps, diarrhea, chest discomfort, sweating, miosis, tearing, salivation, and other excessive respiratory tract secretion, vomiting, cyanosis, muscle twitching, and convulsions. EYES: Irritating. SKIN: Irritating-can cause dermatitis.
Brandgefahr
May be combustible. (NOAA, 2007)
Landwirtschaftliche Anwendung
Insecticide, Fungicide, Bactericide, Acaricide: Naled is a fast-acting, nonsystemic contact and stomach
insecticide used to control aphids, mites, mosquitoes,and flies on crops and in greenhouses, mushroom houses,
animal and poultry houses, kennels, food-processing
plants, and aquaria and in outdoor mosquito control. Liquid
formulations can be applied to greenhouse heating pipes to
kill insects by vapor action. It has been used by veterinarians
to kill parasitic worms (other than tapeworms) in dogs.
Naled may no longer be used in and around the home by
residents or professional applicators. Naled is available in
dust, emulsion concentrate, liquid, and ULV formulations.
Also used in cooling towers, veterinary medicine, pulp and
paper mill systems, hospitals, swimming pools, and bathrooms.
A U.S. EPA restricted Use Pesticide (RUP). Not
approved for use in EU countries. Registered for use in
the U.S.
Handelsname
AI3-24988®; ARTHODIBROM®;
BROMCHLOPHOS®; BROMEX®; DIBROM®;
FLYKILLER®; LUCANAL®; HIBROM®; ORTHO®
4355; ORTHODIBROM®; ORTHODIBROMO®;
PROKIL® Naled; TRUMPET®
Kontakt-Allergie
Naled is an organophosphate cholinesterase inhibitor
that is used as an insecticide and acaricide. Sensitization
seems to be very rare.
mögliche Exposition
A potential danger to those involved
in the manufacture, formulation, and application of this
insecticide, fungicide, bactericide, acaricide. Also used in
cooling towers, veterinary medicine, pulp and paper mill
systems; hospitals, swimming pools; and bathrooms.
Carcinogenicity
When dogs were given 0.2, 2.0,
or 20 mg/kg/day naled by gavage for 1 year, cholinergic signs
(soft stools/diarrhea, salivation, and emesis), increases in
mineralization of spinal cord, and mild testicular degeneration
in males occurred at 2 and 20 mg/kg/day dose
levels . Erythrocyte and brain cholinesterase activities
were depressed at the same dose levels. Anemia also
occurred at 2 and 20 mg/kg/day, and erythrocyte count,
hemoglobin, and hematocrit were reduced. At 20 mg/kg/
day dose level, liver and kidney weights increased but
these were not accompanied by histopathological changes.
There was no evidence of carcinogenicity.
Environmental Fate
Chemical/Physical. Completely hydrolyzed in water within 2 days (Windholz et al.,
1983). In the presence of metals or reducing agents, naled loses bromine, forming dichlorvos
(Hartley and Kidd, 1987)
Naled emits toxic fumes of bromines, chlorides and phosphorus oxides when heated
to decomposition (Lewis, 1990).
Stoffwechselwegen
Naled is produced by the photochemical bromination of the dichlorovinyl
moiety of dichlorvos. The main route of naled metabolism and transformation
in the environment is through debromination to dichlorvos
which is probably the active cholinesterase inhibitor in vivo. Naled is also
rapidly hydrolysed to bromodichloroacetaldehyde in aqueous environments:
consequently much of its detoxification is likely to be via a nonenzymatic
hydrolytic route.
Versand/Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. UN2783 Organophosphorus pesticides,
solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
UN3018 Organophosphorus pesticides, liquid, toxic,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Inkompatibilitäten
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Hydrolyzed in presence of
water. Degraded by sunlight. Decomposes when heated; on
contact with acids, acid fumes; bases, producing fumes of
hydrogen chloride, hydrogen bromide, phosphorous oxides.
Reacts with acids, strong oxidizers in sunlight. Slowly
reacts with water; hydrolysis is; corrosive to metals.
Attacks some plastics, rubber and coatings.
Waste disposal
This pesticide is more
stable to hydrolysis than dichlorvos (50% hydrolysis at pH
9 @ 37.5℃ in 301 minutes). It is unstable in alkaline conditions,
in presence of iron; and is degraded by sunlight.
About 10% hydrolysis per day is obtained in ambient
water. Incineration is recommended for large amounts.
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must
be disposed properly by following package label directions
or by contacting your local or federal environmental control
agency, or by contacting your regional EPA office.
Naled (ISO) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
