O-(2,4-Dichlorophenyl)-O-ethyl-S-propyldithiophosphat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Prothiofos is a colorless liquid. It is nearly insoluble in water (1.7 mg/L
at 20 ?C) but readily soluble in most organic solvents. Log
Kow = 5.67. It is relatively stable in aqueous media; DT
50
values (22 ?C) at pH 4, 7, and 9 are 120, 280, and 12 d, respectively.
Verwenden
Prothiofos is used to control chewing insects in a range of crops
including vegetables, fruit, maize, sugar cane and ornamentals.
Definition
ChEBI: An organic thiophosphate that is the 2,4-dichlorophenyl ester of O-ethyl S-propyl dithiophosphoric acid.
Stoffwechselwegen
A report by Nihon Tokushu Noyaku Seizo K.K. (1979) (now Nhon Bayer
Agrochem K.K.) has summarised the nature of the photolysis products
and metabolites formed by prothiofos in plants, insects, chicken, mice,
rats, guinea-pigs and rabbits. Major routes for the metabolism of prothiofos
include activation via oxidative desulfuration to the oxon and detoxification
by dearylation to give 2,4-dichlorophenol which occur in all
media. In addition, cleavage of the P-S bond and loss of the propanethiol
moiety is an important detoxification mechanism in mammals but not
insects and dechlorination by reductive loss of the 2-chlorine substituent
in the phenyl ring occurs in soil, plants and photochemically. Stage II
metabolism results in the formation of the glucoside of 2,4-dichlorophenol
in plants and insects and the glucuronide and sulfate ester in mammals.
Stoffwechsel
The principal metabolic routes are
activation by oxidative desulfuraton and detoxification by
dearylation and cleavage of the P?S bond in both animals
and plants. Prothiofos is strongly adsorbed in soil; the
half-life under field conditions is 1–2 months.
O-(2,4-Dichlorophenyl)-O-ethyl-S-propyldithiophosphat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
