2-Aminoethylmethylsulfone hydrochloride
- CAS No.
- 104458-24-4
- Chemical Name:
- 2-Aminoethylmethylsulfone hydrochloride
- Synonyms
- 2-Methanesulfonylethan-1-aMine hydrochloride;2-(methylsulfonyl)ethan-1-amine hydrochloride;2-(Methylsulfonyl)Ethylamine HCl;CL126;)ethanamine hydrochL;Lapatinib hyrochloride;Lapatinib Intermediate 1;2-AMINOETHYLMETHYLSULFONE HCL;2-Methane sulfonyl ethyl aMine;2-(Methylsulfonyl)ethanaMine HCl
- CBNumber:
- CB01113134
- Molecular Formula:
- C3H10ClNO2S
- Molecular Weight:
- 159.63
- MDL Number:
- MFCD03840162
- MOL File:
- 104458-24-4.mol
- MSDS File:
- SDS
| Melting point | 168.0 to 172.0 °C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | AMYYUKGKCJKCBI-UHFFFAOYSA-N |
| CAS DataBase Reference | 104458-24-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319 |
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
| HS Code | 29211990 |
2-Aminoethylmethylsulfone hydrochloride price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2464 | 2-Aminoethyl Methyl Sulfone Hydrochloride >98.0%(N)(T) | 104458-24-4 | 5g | $44 | 2024-03-01 | Buy |
| TRC | M339108 | 2-(Methylsulfonyl)ethylamineHydrochloride | 104458-24-4 | 2.5g | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA53226 | 2-Aminoethylmethylsulfone Hydrochloride | 104458-24-4 | 10g | $120 | 2021-12-16 | Buy |
| Apolloscientific | OR12674 | 2-Aminoethylmethylsulphone hydrochloride | 104458-24-4 | 10g | $129 | 2021-12-16 | Buy |
| SynQuest Laboratories | 8163-5-X0 | 2-Aminoethylmethylsulfone hydrochloride | 104458-24-4 | 10g | $152 | 2021-12-16 | Buy |
2-Aminoethylmethylsulfone hydrochloride Chemical Properties,Uses,Production
Description
Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells.
Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.
Chemical Properties
Off-white to yellow solid
Uses
2-(Methylsulfonyl)ethylamine Hydrochloride is used in the synthetic preparation of potent and selective PI3Kδ inhibitors.
2-Aminoethylmethylsulfone hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Qiangshan New Material Co.,Ltd. | +86-13951653990 +86-13951653990 | jjx35259720@hotmail.com | China | 27 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7613 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from 2-Aminoethylmethylsulfone hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-16 | 2-Aminoethylmethylsulfone hydrochloride
104458-24-4
|
US $5.00-0.10 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-07-19 | 2-Aminoethylmethylsulfone hydrochloride
104458-24-4
|
US $30.00 / KG | 1KG | 99% | 100 Tons | Wuhan wingroup Pharmaceutical Co., Ltd | |
 |
2023-04-13 | 2-Aminoethylmethylsulfone hydrochloride
104458-24-4
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
-
- 2-Aminoethylmethylsulfone hydrochloride
104458-24-4
- US $5.00-0.10 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Aminoethylmethylsulfone hydrochloride
104458-24-4
- US $30.00 / KG
- 99%
- Wuhan wingroup Pharmaceutical Co., Ltd
-
- 2-Aminoethylmethylsulfone hydrochloride
104458-24-4
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
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