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3-Oxocyclobutanecarboxylic acid

3-Oxocyclobutanecarboxylic acid structure

CAS No.: 23761-23-1

Chemical Name:: 3-Oxocyclobutanecarboxylic acid

Synonyms: 3-oxocyclobutane-1-carboxylic acid;3-OXO-CYCLOBUTANECARBOXYLIC ACID;3-oxocyclobutane-1,1-dicarboxylic acid;3-OxocycL;IFLAB-BB F2124-0041;1-Carboxy-3-oxocyclobutane;3-Oxocyclobutanecarboxylic;3-Oxocyclobutanecarboxyli...;Oxocyclobutanecarboxylic acid;3-Oxycyclobutanecarboxylic acid

CBNumber:: CB0111483

Molecular Formula:: C5H6O3

Molecular Weight:: 114.1

MDL Number:: MFCD00100900

MOL File:: 23761-23-1.mol

Last updated:2024-04-15 15:30:59

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3-Oxocyclobutanecarboxylic acid Properties

Melting point	69-70℃
Boiling point	296°C
Density	1.431
Flash point	147°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Solid
pka	4.35±0.20(Predicted)
color	Off-white
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C5H6O3/c6-4-1-3(2-4)5(7)8/h3H,1-2H2,(H,7,8)
InChIKey	IENOFRJPUPTEMI-UHFFFAOYSA-N
SMILES	C1(C(O)=O)CC(=O)C1
CAS DataBase Reference	23761-23-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Danger
Hazard statements	H315-H319-H335
Precautionary statements	P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes	Xn
Risk Statements	22
Safety Statements	26-37-60
TSCA	No
HS Code	29189900

3-Oxocyclobutanecarboxylic acid price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS004694	3-Oxocyclobutanecarboxylic acid AldrichCPR	23761-23-1	100mg	$70.9	2024-03-01	Buy
TCI Chemical	O0392	3-Oxocyclobutanecarboxylic Acid >97.0%(GC)(T)	23761-23-1	1g	$16	2024-03-01	Buy
TCI Chemical	O0392	3-Oxocyclobutanecarboxylic Acid >97.0%(GC)(T)	23761-23-1	5g	$52	2024-03-01	Buy
Alfa Aesar	H64774	3-Oxocyclobutanecarboxylic acid, 98%	23761-23-1	5g	$51.65	2024-03-01	Buy
Alfa Aesar	H64774	3-Oxocyclobutanecarboxylic acid, 98%	23761-23-1	25g	$207.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
CDS004694	100mg	$70.9	Buy
O0392	1g	$16	Buy
O0392	5g	$52	Buy
H64774	5g	$51.65	Buy
H64774	25g	$207.65	Buy

3-Oxocyclobutanecarboxylic acid Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

3-Oxocyclobutanecarboxylic Acid (cas# 23761-23-1) is a compound useful in organic synthesis.

Application

3-Oxocyclobutanecarboxylic acid is a very important medicine intermediate, it is widely applied in the synthetic of tens kinds of bulk drugs, such as ACK1 antibody, the MDM2 antagonist, the JAK inhibitor, CETP inhibitor, kinase inhibitor, the PDE10 inhibitor, thrombin inhibitors and in autoimmunization chronic inflammatory diseases and antitumor drug, all being used to.

Preparation

The target product 3-oxocyclobutanecarboxylic acid is obtained by adopting acetone, bromine, and malononitrile as raw materials, adopting ethanol, DMF (dimethyl formamide), and water as solvents, adopting sodium iodide as an activating agent and tetrabutylammonium bromide (TBAB) as a phase transfer catalyst through three-step reaction.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 3841, 1988 DOI: 10.1021/jo00251a033

3-Oxocyclobutanecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3,3-Difluorocyclobutanecarboxylic acid 5,8-Dioxaspiro[3.4]octane-2-Methanol Methyl 3-broMocyclobutane-1-carboxylate 3-BroMocyclobutanone 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester

Methyl cis-3-hydroxycyclobutanecarboxylate Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI) 3-METHYLENECYCLOBUTANECARBOXYLIC ACID 3-Oxo-cyclobutanecarboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester isopropyl3-oxocyclobutane-1-carboxylate

Cyclobutanecarboxamide, N,N-dimethyl-3-oxo-, diethyl acetal (6CI) 3,3-difluorocyclobutane-1-carbonyl chloride N-((3-chloropyrazin-2-yl)Methyl)-3-oxocyclobutanecarboxaMide

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3-Oxocyclobutanecarboxylic acid Suppliers

Global( 501)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ChemExpress	+86-021-58950125	info@chemexpress.com	China	557	58
Shaoxing Fangxiao Chemical Co., LTD	+86-13456999252 +86-13868192239	kenny@fangxiaochem.com	China	50	58
Lianhe Aigen Pharmatech Co.,Ltd.	+86-18918657159 +86-18918657159	sales-Aigen@lianhetech.com	China	305	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Hangzhou ICH Biofarm Co., Ltd	+undefined8613073685410	sales@ichemie.com	China	985	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7786	58
Wuhan Xinhao Biotechnology Co., Ltd	+86-18120578002 +86-18120578002	xinhao-6@xinhaoshengwu.com	China	350	58
airuikechemical co., ltd.	+undefined86-15315557071	sales02@airuikechemical.com	China	994	58

Supplier	Advantage
ChemExpress	58
Shaoxing Fangxiao Chemical Co., LTD	58
Lianhe Aigen Pharmatech Co.,Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Hangzhou ICH Biofarm Co., Ltd	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Wuhan Xinhao Biotechnology Co., Ltd	58
airuikechemical co., ltd.	58

View Lastest Price from 3-Oxocyclobutanecarboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-24	3-Oxocyclobutanecarboxylic acid 23761-23-1	US $874.00-862.00 / kg	1kg	99.99%	100Tons	Hebei Dangtong Import and export Co LTD
2024-04-15	3-Oxocyclobutanecarboxylic acid 23761-23-1	US $5.00-0.10 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2024-04-12	3-Oxocyclobutanecarboxylic acid 23761-23-1	US $0.00 / kg	1kg	99%	2000ton	Shaanxi Haibo Biotechnology Co., Ltd

3-Oxocyclobutanecarboxylic acid
23761-23-1
US $874.00-862.00 / kg
99.99%
Hebei Dangtong Import and export Co LTD

3-Oxocyclobutanecarboxylic acid
23761-23-1
US $5.00-0.10 / KG
99%
Henan Fengda Chemical Co., Ltd

3-Oxocyclobutanecarboxylic acid
23761-23-1
US $0.00 / kg
99%
Shaanxi Haibo Biotechnology Co., Ltd

3-Oxocyclobutanecarboxylic acid Spectrum

3-Oxocyclobutanecarboxylic acid(23761-23-1)¹HNMR

23761-23-1(3-Oxocyclobutanecarboxylic acid)Related Search:

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