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Methyl thioglycolate

CAS No.
2365-48-2
Chemical Name:
Methyl thioglycolate
Synonyms
Methyl 2-mercaptoacetate;MTG;METHYL MERCAPTOACETATE;THIOGLYCOLIC ACID METHYL ESTER;MERCAPTOACETIC ACID METHYL ESTER;METG;usafek-7119;USAF ek-7119;Articaine-003;Methy Diglycolate
CBNumber:
CB0165491
Molecular Formula:
C3H6O2S
Molecular Weight:
106.14
MDL Number:
MFCD00004873
MOL File:
2365-48-2.mol
MSDS File:
SDS
Last updated:2024-04-08 17:36:13

Methyl thioglycolate Properties

Melting point -24 °C
Boiling point 42-43 °C/10 mmHg (lit.)
Density 1.187 g/mL at 25 °C (lit.)
refractive index n20/D 1.466(lit.)
Flash point 86 °F
storage temp. Store below +30°C.
solubility 40g/l
form Liquid
pka 8.04±0.10(Predicted)
color Clear colorless
Water Solubility 40 g/L (20 ºC)
Sensitive Air Sensitive
BRN 506259
InChIKey MKIJJIMOAABWGF-UHFFFAOYSA-N
CAS DataBase Reference 2365-48-2(CAS DataBase Reference)
EWG's Food Scores 1-3
FDA UNII O1608LA9EL
NIST Chemistry Reference Acetic acid, mercapto-, methyl ester(2365-48-2)
EPA Substance Registry System Acetic acid, mercapto-, methyl ester (2365-48-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06
Signal word  Danger
Hazard statements  H226-H301-H315-H319-H332-H335
Precautionary statements  P210-P233-P301+P310-P303+P361+P353-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,T
Risk Statements  10-20/22-36/37/38-25
Safety Statements  26-36/37-45-36/37/39-28A
RIDADR  UN 1992 3/PG 3
WGK Germany  1
RTECS  AI7350000
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29309070
Toxicity mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,
NFPA 704
2
2 0

Methyl thioglycolate price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 108995 Methyl thioglycolate 95% 2365-48-2 5g $36.4 2024-03-01 Buy
Sigma-Aldrich 108995 Methyl thioglycolate 95% 2365-48-2 100g $43.2 2024-03-01 Buy
TCI Chemical T1287 Methyl Thioglycolate >98.0%(GC) 2365-48-2 25g $25 2024-03-01 Buy
TCI Chemical T1287 Methyl Thioglycolate >98.0%(GC) 2365-48-2 100g $49 2024-03-01 Buy
Alfa Aesar L03783 Methyl mercaptoacetate, 98% 2365-48-2 100g $29.65 2024-03-01 Buy
Product number Packaging Price Buy
108995 5g $36.4 Buy
108995 100g $43.2 Buy
T1287 25g $25 Buy
T1287 100g $49 Buy
L03783 100g $29.65 Buy

Methyl thioglycolate Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Methyl thioglycolate was used in the preparation of 3-carbomethoxy-4- oxotetrahydrothiopyran, 2- and 4-carbomethoxy-3-oxotetrahydrothiophene. It is used to prepare methyl thioglycolate and aminoethanethiol conjugated gold nanorods.

Uses

Methyl Thioglycolate is an derivative of Thioglycolic Acid (T350760), an organic compound containing both a thiol and a carboxylic acid functional groups. Thioglycolic Acid and its derivatives are oft en used in organic synthesis as a nucleophile in thioglycolysis reactions and is also used as a S transfer agent for sulfonyl chloride synthesis. Methyl Thioglycolate have been studied for the its inf luence on neocarzinostatin activation and expression of DNA damage.

Application

Methyl thioglycolate is a chemical compound that is used in the pharmaceutical industry as an intermediate. It has been used to synthesize anti-inflammatory drugs, such as aspirin and ibuprofen, and also for the treatment of autoimmune diseases. Methyl thioglycolate binds to amino acids on the surface of bacteria, which prevents them from functioning properly. This binding causes the cells to stop growing and die.

Definition

Methyl thioglycolate are widely used in free-radical photoinitiated polymerization reactions. In particular, the use of methyl thioglycolate (MTG), CH3OC(O)CH2SH, results in greater photopolymerization reaction rates, attributed to a weakening of the sulfur–hydrogen bond by hydrogen bonding of the thiol group. MTG constitutes the smaller exponent of the series of CH3OC(O)(CH2)nSH compounds, reported as intermediated in the organic sulfur cycle in marine environments, produced by marine phytoplankton.

General Description

Methyl thioglycolate reacts with nonprotein component of the antitumor antibiotic neocarzinostatin to form 1:1 adduct. It reacts with isothiocyanate to form Rhodanine.

67-56-1
68-11-1
2365-48-2
Synthesis of Methyl thioglycolate from Methanol and Mercaptoacetic acid
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View Lastest Price from Methyl thioglycolate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl thioglycolate pictures 2024-04-16 Methyl thioglycolate
2365-48-2
US $1.00 / KG 1KG 99% 500mt/year Jinan Finer Chemical Co., Ltd
Methyl thioglycolate pictures 2024-04-15 Methyl thioglycolate
2365-48-2
US $1.00 / mg 100mg 0.99 5ton/month ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
methyl thioglycolate pictures 2024-04-08 methyl thioglycolate
2365-48-2
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
METG METHYL THIOGLYCOLATE METHYL THIOGLYCOLLATE mercapto-aceticacimethylester Methanethiol, methoxy- methoxy-methanethio Methyl alpha-mercaptoacetate Methyl ester of thioglycolic acid Methyl sulfanylacetate methyl2-mercaptoacetate Thioglykolsaeure-methylester USAF ek-7119 usafek-7119 Sulfhydryl methyl acetate Methylthioglycolate,98% Acetic acid, mercapto-, methyl ester Thioglyonic Acid Methyl Ester, , Methylmercaptoacetat Thioglycol methylate Thioglycollic acid methyl ester Methyl thioglycolate,95% Mercaptoacetic Acid Methyl Ester Methyl Mercaptoacetate Thioglycolic Acid Methyl Ester Methy Diglycolate Methyl thioglycolate,Methyl mercaptoacetate Methyl thioglycolate, 95% 100GR Methyl thioglycolate, 95% 500GR Methyl thioglycolate, 95% 5GR Methyl mercaptoacetate Methyl thioglycolate Mercaptoacetic acid methylester Methyl mercaptoacetate Mercaptoacetic Acid Methyl Ester Thioglycolic Acid Methyl Ester Methylethioglycolate Methyl sulphanylacetate, Methyl mercaptoacetate Acetic acid,2-Mercapto-, Methyl ester Methyl thioglycolate 95% Methyl thioglycolate, 99%, 99% Methyl thioglycolate Joyce Articaine-003 METHYL THIOGLYCOLATE Extra Pure MERCAPTOACETIC ACID METHYL ESTER METHYL MERCAPTOACETATE THIOGLYCOLIC ACID METHYL ESTER Methyl 2-mercaptoacetate MTG Tetramethylammonium hydroxide pentahydrate 10424-65-4 2365-48-2 HSCH2CO2CH3 HSCH2COOCH3 Organic Building Blocks Thiols/Mercaptans Sulfur Compounds Building Blocks 2365-48-2