OPHIOBOLIN B
- CAS No.
- 5601-74-1
- Chemical Name:
- OPHIOBOLIN B
- Synonyms
- OPHIOBOLIN B;Cochliobolin B;Ophiobolin B (Cochliobolin B);Cochliobolin B, Zizanin B, Ophiobolsin A;3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-
- CBNumber:
- CB0202198
- Molecular Formula:
- C25H38O4
- Molecular Weight:
- 402.57
- MDL Number:
- MFCD08061872
- MOL File:
- 5601-74-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P302+P352-P305+P351+P338 |
| HS Code | 2932190090 |
OPHIOBOLIN B price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18432 | Ophiobolin B ≥95% | 5601-74-1 | 1mg | $335 | 2024-03-01 | Buy |
| Cayman Chemical | 18432 | Ophiobolin B ≥95% | 5601-74-1 | 5mg | $1085 | 2024-03-01 | Buy |
| TRC | O669205 | OphiobolinB | 5601-74-1 | 1mg | $265 | 2021-12-16 | Buy |
| Usbiological | O7024-01 | Ophiobolin B | 5601-74-1 | 1mg | $523 | 2021-12-16 | Buy |
| Usbiological | 461592 | Ophiobolin B | 5601-74-1 | 1mg | $602 | 2021-12-16 | Buy |
OPHIOBOLIN B Chemical Properties,Uses,Production
Uses
Ophiobolin B is a fungal phytotoxin and inhibits calmodulin (a protein involved in calcium regulation). Ophiobolin B also exhibit antibacterial and antitumor activities.
Uses
Calmodulin is a calcium-sensing protein that regulates a wide array of proteins involved in diverse cellular functions. Ophiobolin B is a sesterterpenoid fungal phytotoxin that binds and irreversibly antagonizes calmodulin, producing cytotoxic and antimicrobial effects. It induces apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM and in different zygomycetes with MIC values ranging from 25-50 μg/ml.[Cayman Chemical]
Uses
Ophiobolin B is a minor member of a class of phytotoxic metabolites produced by Bipolaris and other genera of plant pathogenic fungi. Ophiobolin B acts by inhibiting calmodulin action in calcium regulation.
OPHIOBOLIN B Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9288 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-61856359 18690052321 | 1027@dideu.com | China | 10011 | 58 |