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4-(3-Chloropropyl)morpholine

4-(3-Chloropropyl)morpholine Structure
4-(3-Chloropropyl)morpholine structure
CAS No.
7357-67-7
Chemical Name:
4-(3-Chloropropyl)morpholine
Synonyms
4-(3-ChL;NSC 38889;NSC 28831;)-morphoL;N-(3-Chloropropyl)M;IFLAB-BB F2108-0002;Gefitinib iMpurity A;Gefitinib IMpurity VI;Gefitinib Impurity 81;3-morpholinopropylchloride
CBNumber:
CB0240217
Molecular Formula:
C7H14ClNO
Molecular Weight:
163.65
MDL Number:
MFCD00039714
MOL File:
7357-67-7.mol
Last updated:2024-03-25 14:24:00
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4-(3-Chloropropyl)morpholine Properties

Melting point NA
Boiling point 115°C/25mmHg(lit.)
Density 1.0409 g/cm3
RTECS QE0488000
refractive index 1.4720-1.4760
Flash point 91 °C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
pka 7.03±0.10(Predicted)
Specific Gravity 1.08
color Colourless to Yellow
InChI InChI=1S/C7H14ClNO/c8-2-1-3-9-4-6-10-7-5-9/h1-7H2
InChIKey PQECODMSWJOUAT-UHFFFAOYSA-N
SMILES N1(CCCCl)CCOCC1
CAS DataBase Reference 7357-67-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 82BVM8E6TN

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  2934999090
NFPA 704
0
2 0

4-(3-Chloropropyl)morpholine price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2602 4-(3-Chloropropyl)morpholine >98.0%(GC)(T) 7357-67-7 5g $29 2024-03-01 Buy
TCI Chemical C2602 4-(3-Chloropropyl)morpholine >98.0%(GC)(T) 7357-67-7 25g $92 2024-03-01 Buy
Alfa Aesar H35222 4-(3-Chloropropyl)morpholine, 95% 7357-67-7 10g $57.65 2024-03-01 Buy
Alfa Aesar H35222 4-(3-Chloropropyl)morpholine, 95% 7357-67-7 50g $185.65 2024-03-01 Buy
TRC C379750 4-(3-Chloropropyl)morpholine 7357-67-7 1g $80 2021-12-16 Buy
Product number Packaging Price Buy
C2602 5g $29 Buy
C2602 25g $92 Buy
H35222 10g $57.65 Buy
H35222 50g $185.65 Buy
C379750 1g $80 Buy

4-(3-Chloropropyl)morpholine Chemical Properties,Uses,Production

Description

4-(3-Chloropropyl)morpholine is a hydrochloride salt of the potent inhibitor 4-(3-chloropropyl)morpholine. It has an inhibitory effect on cancer, and is used in chromatographic science to separate amines from aliphatic hydrocarbons. 4-(3-Chloropropyl)morpholine inhibits epidermal growth factor (EGF) and has been shown to have a potent inhibitory effect on EGF receptor tyrosine kinase activity. It also inhibits the proliferation of cells by inhibiting DNA synthesis. This compound causes cell death through the inhibition of protein synthesis, which may be due to its ability to inhibit nucleophilic reactions that are involved in protein synthesis. 4-(3-Chloropropyl)morpholine can also fluoresce under UV light, which makes it useful for research purposes.

Chemical Properties

Pale Yellow Oil

Uses

Gefitinib intermediate.

Application

4-(3-Chloropropyl)morpholine is an organic synthetic reagent or pharmaceutical intermediate used in the synthesis of gefitinib. It has cancer-inhibiting properties and inhibits epidermal growth factor (EGF). It also inhibits cell proliferation by inhibiting DNA synthesis.

4-(3-Chloropropyl)morpholine synthesis

110-91-8
109-70-6
7357-67-7
Synthesis of 4-(3-Chloropropyl)morpholine from Morpholine and 1-Bromo-3-chloropropane

4-(3-Chloropropyl)morpholine Preparation Products And Raw materials

Raw materials

1-Bromo-3-chloropropane 3-Morpholinopropanol 4-Methoxy-3-[3-(4-morpholinyl)propoxy]benzaldehyde Pentaerythritol tetraacrylate Morpholine

Preparation Products

N-(3-Aminopropyl)morpholine 3-(3-morpholinylpropoxy)-4-methoxybenzonitrile

4-(3-Chloropropyl)morpholine Suppliers

Global( 351)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7786 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 341 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Anqing Chico Pharmaceutical Co., Ltd. 		58
career henan chemical co 		58
Jinan Finer Chemical Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Chongqing Chemdad Co., Ltd 		58

View Lastest Price from 4-(3-Chloropropyl)morpholine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(3-Chloropropyl)morpholine pictures 2024-01-14 4-(3-Chloropropyl)morpholine
7357-67-7
 US $8.00-0.60 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-(3-Chloropropyl)morpholine pictures 2023-11-27 4-(3-Chloropropyl)morpholine
7357-67-7
 US $0.00 / kg 1kg 98% ton Nanjing Fred Technology Co., Ltd
N-(3-Chloropropyl)morpholine pictures 2023-03-12 N-(3-Chloropropyl)morpholine
7357-67-7
 US $0.00 / kg 1kg 98.0%min 100kg LY Global chemicals co.,ltd .

4-(3-Chloropropyl)morpholine Spectrum

N-(3-Chloropropyl)morpholine(7357-67-7)FT-IR

7357-67-7(4-(3-Chloropropyl)morpholine)Related Search:

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Isovanillin Benzonitrile, 5-methoxy-4-[3-(4-morpholinyl)propoxy]-2-nitro- 4-Chloro-3-fluoroaniline

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4-(3-CHLOROPROPYL)-MORPHOLINE HYDROCHLORIDE MORPHOLINOPROPYL CHLORIDE HYDROCHLORIDE N-(3-CHLOROPROPYL)MORPHOLINE HCL 3-morpholinopropylchloride 4-(3-chloropropyl)-morpholin N-(3-Chloropropyl)morpholine 1-Chloro-3-morpholinopropane 3-(Morpholin-4-yl)propyl Chloride 3-Chloro-1-(morpholin-4-yl)propane NSC 28831 NSC 38889 morpholine, 4-(3-chloropropyl)- 4-(3-chloropropyl)morpholine(SALTDATA: FREE) N-(3-Chloropropyl)M 4-(3-Chloropropyl) Morpholine Gefitinib HCL Side Chain Gefitinib IMpurity VI IFLAB-BB F2108-0002 4-(3-CHLORO-PROPYL)-MORPHOLINE 4-(3-CHLOROPROPYL)MORPHOLINE HCL 1-Chloro-3-(morpholin-4-yl)propane Gefitinib iMpurity A 4-(3-ChL 4-(3-Chloropropyl)morpholine > Gefitinib Impurity 81 )-morphoL 4-(3-Chloropropyl)morpholineQ: What is 4-(3-Chloropropyl)morpholine Q: What is the CAS Number of 4-(3-Chloropropyl)morpholine Q: What is the storage condition of 4-(3-Chloropropyl)morpholine Q: What are the applications of 4-(3-Chloropropyl)morpholine Gefitinib Intermediate VIII N-(3-Chloropropyl)morpholin 7357-67-7 ETHER Gefitinib Aromatic Morpholines Benzomorpholines & Benzothiomorpholines Methyl Halides Morpholines & Thiomorpholines API intermediates Heterocycles Intermediates Intermediates & Fine Chemicals Pharmaceuticals Benzomorpholines & Benzothiomorpholines Methyl Halides Morpholines & Thiomorpholines