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ChemicalBook >> CAS DataBase List >>2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Structure
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE structure
CAS No.
145100-51-2
Chemical Name:
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Synonyms
Comins;N-(5-CHLORO-2-PYRIDYL)TRIFLIMIDE;N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-;N-(5-CHLORO-2-PYRIDYL)BIS(TRIFLUOROMETHANESULFONIMIDE);N,N-BIS(TRIFLUOROMETHYLSULFONYL)-5-CHLORO-2-PYRIDYLAMINE;2-[N,N-BIS(TRIFLUOROMETHYLSULPHONYL)AMINO]-5-CHLOROPYRIDINE;N-(5-Chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide;Comins'reagent;Comins Triflating Reagent;N-(5-Chloropyridin-2-yl)triflimide
CBNumber:
CB0248253
Molecular Formula:
C7H3ClF6N2O4S2
Molecular Weight:
392.68
MDL Number:
MFCD00191833
MOL File:
145100-51-2.mol
MSDS File:
SDS
Last updated:2023-10-31 16:47:27
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2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Properties

Melting point 45-47 °C(lit.)
Boiling point 77-90°C/0.2mmHg
Density 1.892±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Benzene (Slightly)
form Solid
pka -7.71±0.10(Predicted)
color yellow
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 5833971
Stability Moisture Sensitive, Unstable in DMSO Solution
InChIKey TUFGVZMNGTYAQD-UHFFFAOYSA-N
CAS DataBase Reference 145100-51-2(CAS DataBase Reference)
FDA UNII WS933U9U66

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
F  9
Hazard Note  Irritant
HazardClass  AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD
HS Code  29350090
NFPA 704
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2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 403644 N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) 96% 145100-51-2 1g $28.7 2024-03-01 Buy
Sigma-Aldrich 403644 N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) 96% 145100-51-2 5g $127 2024-03-01 Buy
TCI Chemical B1865 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent] >96.0%(GC) 145100-51-2 5g $83 2024-03-01 Buy
TCI Chemical B1865 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent] >96.0%(GC) 145100-51-2 25g $412 2024-03-01 Buy
Alfa Aesar L16929 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99% 145100-51-2 1g $37.65 2024-03-01 Buy
Product number Packaging Price Buy
403644 1g $28.7 Buy
403644 5g $127 Buy
B1865 5g $83 Buy
B1865 25g $412 Buy
L16929 1g $37.65 Buy

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Chemical Properties,Uses,Production

Chemical Properties

White to pale yellow crystalline solid

Uses

Reactant for:
Suzuki-Miyaura cross coupling
Synthesis of nicotinic acetylcholine receptor-selective ligands
Enantioselective desymmetrizing palladium catalyzed carbonylation reactions
Synthesis of high affinity niacin receptor GPR109A agonists
Preparation of heteroaromatics

Uses

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

Methanesulfonic acid, 1,1,1-trifluoro-, 3-(1,1-dimethylethyl)phenyl ester 8-Benzyl-3-(trifluoroMethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene 4-[2-[5,6-Dihydro-5,5-dimethyl-8-[[(trifluoromethyl)sulfonyl]oxy]-2-naphthalenyl]ethynyl]benzoic Acid Ethyl Ester

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Suppliers

Global( 241)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Accela ChemBio Inc. 		58

View Lastest Price from 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE pictures 2024-01-02 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
145100-51-2
 US $50.00-500.00 / kg 10kg 0.99 20tons Zibo Hangyu Biotechnology Development Co., Ltd
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE pictures 2023-08-18 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
145100-51-2
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE pictures 2022-11-04 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
145100-51-2
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Guanlang Biotechnology Co., Ltd.

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Spectrum

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE(145100-51-2)IR2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE(145100-51-2)FT-IR

145100-51-2(2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE)Related Search:

Mesitylene-2-sulfonyl chloride 2-[N,N-BIS(TRIFLUOROMETHYLSULFONYL)AMINO]PYRIDINE 2-Amino-5-chloropyridine Trifluoromethanesulfonamide 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Trifluoromethanesulfonimide

1of2

Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE) 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine ,98% Comins Triflating Reagent N-(5-Chloro-2-pyridyl)triflimide N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide Comins Triflating Reagent N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoroMethane)sulfonylMethanesulfonaMide 2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine N-(5-Chloropyridin-2-yl)triflimide 2-[N,N-BIS(TRIFLUOROMETHANESULPHONYL)AMINO]-5-CHLOROPYRIDINE 2-[N,N-BIS(TRIFLUOROMETHYLSULFONYL)AMINO]-5-CHLOROPYRIDINE 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Bistrifluoromethylsulfonylaminochloropyridine Comins'reagent N-(5-chloropyridin-2-yl)trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide n-(5-chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide 2-[N,N-bis(trifluoromethylsulphony)amino]-5-chloropyridine 2-[N,N-BIS(TRIFLUROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE N-(5-chloro-2-pyridyl)bis(trifluromethanesulfonimide 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent] 2-N,N-Bis(trifluoromethanesulfonyl)aminoü-5-chloropyridine, 99% 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine[TriflatingReagent]> Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE ISO 9001：2015 REACH N-(5-CHLORO-2-PYRIDYL)BIS(TRIFLUOROMETHANESULFONIMIDE) N,N-BIS(TRIFLUOROMETHYLSULFONYL)-5-CHLORO-2-PYRIDYLAMINE Comins N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N- 2-[N,N-BIS(TRIFLUOROMETHYLSULPHONYL)AMINO]-5-CHLOROPYRIDINE N-(5-CHLORO-2-PYRIDYL)TRIFLIMIDE N-(5-Chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide 145100-51-2 C7Cl1F6H3N2O4S2 C7H3ClF6N2O4S2 Halopyridines Chloropyridines Building Blocks C7 and C8 Heterocyclic Building Blocks Pyridines Chloropyridines Halopyridines