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Tributyltin chloride

CAS No.
1461-22-9
Chemical Name:
Tributyltin chloride
Synonyms
TRIBUTYLTIN CHLORIDE;tributylchlorostannane;TRI-N-BUTYLTIN CHLORIDE;TBTC;TBTCL;Tributylzinnchlorid;Tributylstannyl chloride;N-TRI-TERT-BUTYLTIN CHLORIDE;wr3396;WR 3396
CBNumber:
CB0262161
Molecular Formula:
C12H27ClSn
Molecular Weight:
325.51
MDL Number:
MFCD00000521
MOL File:
1461-22-9.mol
MSDS File:
SDS
Last updated:2024-03-25 13:57:35

Tributyltin chloride Properties

Melting point -9 °C
Boiling point 171-173 °C25 mm Hg(lit.)
Density 1.2 g/mL at 25 °C(lit.)
vapor pressure <0.01 mm Hg ( 20 °C)
refractive index n20/D 1.492(lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility 0.017g/l
form liquid
Specific Gravity 1.186
color colorless
Water Solubility PRACTICALLY INSOLUBLE
Sensitive Moisture Sensitive
BRN 3535715
Exposure limits ACGIH: TWA 0.1 mg/m3; STEL 0.2 mg/m3 (Skin)
NIOSH: IDLH 25 mg/m3; TWA 0.1 mg/m3
Stability Hygroscopic
InChIKey GCTFWCDSFPMHHS-UHFFFAOYSA-M
LogP 2.21 at 23℃
CAS DataBase Reference 1461-22-9(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances TRIBUTYLTIN CHLORIDE
EWG's Food Scores 1
FDA UNII CA82T4QR5F
NIST Chemistry Reference Tri-n-butyltin chloride(1461-22-9)
EPA Substance Registry System Tributyltin chloride (1461-22-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301-H312-H315-H317-H319-H360FD-H372-H410
Precautionary statements  P202-P273-P280-P301+P310-P302+P352+P312-P305+P351+P338
Hazard Codes  T,N
Risk Statements  21-25-36/38-48/23/25-50/53
Safety Statements  35-36/37/39-45-60-61-26
RIDADR  UN 2788 6.1/PG 3
WGK Germany  3
RTECS  WH6820000
3-9-21
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29310095
NFPA 704
1
3 0

Tributyltin chloride price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T50202 Tributyltin chloride 96% 1461-22-9 5g $43.9 2024-03-01 Buy
Sigma-Aldrich 442869 Tributyltin chloride analytical standard 1461-22-9 500mg $83.5 2024-03-01 Buy
Sigma-Aldrich 45713 TBTC PESTANAL 1461-22-9 250mg $45.6 2022-05-15 Buy
Alfa Aesar A10746 Tri-n-butyltin chloride, 96% 1461-22-9 50g $58.4 2023-06-20 Buy
Alfa Aesar A10746 Tri-n-butyltin chloride, 96% 1461-22-9 250g $209 2023-06-20 Buy
Product number Packaging Price Buy
T50202 5g $43.9 Buy
442869 500mg $83.5 Buy
45713 250mg $45.6 Buy
A10746 50g $58.4 Buy
A10746 250g $209 Buy

Tributyltin chloride Chemical Properties,Uses,Production

Description

Tributyltin chloride is also as Chlorotributyltin, is the chloride of tributyltin. It is a biocide that contaminates foods, especially shellfish. It is an endocrine disrupter in several marine species and is neurotoxic and immuno-toxic in mammals. It has been used as a heat stabilizer, agricultural pesticide and component of antifouling paints2. However, it is perhaps the most acutely toxic chemical to aquatic organisms ever deliberately introduced to water. It has been demonstrated to have an adverse effect on shellfish in France and England, and as a consequence the use of tributyltin‐containing antifouling paints has been restricted in these countries. Other countries have banned the use of tributyltin‐containing antifouling paints or are contemplating restrictions3.

References

  1. Cooke, G. M., et al. Food & Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association 42.2(2004):211-220.
  2. Nakatsu, Yusuke, Y. Kotake, and S. Ohta. "Tributyltin-induced cell death is mediated by calpain in PC12 cells."Neurotoxicology 27.4(2006):587-593.
  3. Maguire, R. James. "Environmental aspects of tributyltin." Applied Organometallic Chemistry 1.6(1987):475-498.

Chemical Properties

Colorless or light yellow clear liquid. Soluble in the common organic solvents; including alcohol, heptane, benzene, and toluene; insoluble in cold water, but hydrolyzes in hot water.

Uses

Tributyltin Chloride is a triorganotin compound with insecticidal acitivity. It is an endocrine disruptor as well as an inhibitor for the V-ATPases (potential targets in the treatmen t of diseases such as osteoporosis and cancer). Tributyltin Chloride has the functions of antiseptic, sterilization and mildew proof and widely used in wood preservation, ship paint, etc. Further, it is used in hot end glass coating and rodent-repellent for cable coatings.

Preparation

Tributyltin chloride is prepared by a redistribution reaction by combining stannic chloride and tetrabutyltin:
3 (C4H9)4Sn + SnCl4 → 4 (C4H9)3SnCl.

Definition

ChEBI: Tributyltin chloride is an inorganic molecular entity.

Hazard

A poison by ingestion and skin contact. A severe eye irritant. Tributyl tin compounds are extremely toxic to marine life.

Flammability and Explosibility

Not classified

Toxicology

Tributyltin chloride (TBTCL) is a widely used biocide and heat stabiliser for PVC compositions. TBTCL has been detected in humans and may cause harmful effects on the thyroid, cardiovascular and other organs in humans. It is also an endocrine disruptor with toxic effects on the male reproductive system.TBTCL causes apoptosis and cell cycle arrest. Activation of endoplasmic reticulum stress and inhibition of autophagy are responsible for TBTCL-induced apoptosis and cell cycle arrest. 

Global( 256)Suppliers
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View Lastest Price from Tributyltin chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Chlorotributyltin pictures 2023-08-18 Chlorotributyltin
1461-22-9
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Tributyltin Chloride pictures 2022-08-24 Tributyltin Chloride
1461-22-9
US $100.00 / kg 1kg 99% 100 tons Hebei Duling International Trade Co. LTD
Chlorotributyltin pictures 2021-10-19 Chlorotributyltin
1461-22-9
US $9.90 / KG 1KG 99% 5tons Hebei Guanlang Biotechnology Co., Ltd.
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