ChemicalBook >> CAS DataBase List >>3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-

3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-

CAS No.
108466-89-3
Chemical Name:
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
Synonyms
2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid;Boc-AEEA-OH;2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid;Boc-O 2 Oc-OH;2-diMethyl-4-oxo-;BocNH-PEG2-CH2COOH;NHBoc-PEG2-CH2COOH;Boc-N-amido-PEG2-CH2CO2H;t-Boc-N-amido-PEG2-CH2CO2H;t-Boc-N-Amido-PEG2-CH2COOH
CBNumber:
CB02639228
Molecular Formula:
C11H21NO6
Molecular Weight:
263.29
MDL Number:
MFCD17019374
MOL File:
108466-89-3.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Properties

Boiling point 425.7±30.0 °C(Predicted)
Density 1.145±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 3.40±0.10(Predicted)
form liquid
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2918999090

3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 901577 t-Boc-N-amido-PEG2-CH2CO2H ≥95% 108466-89-3 50MG $34.4 2023-06-20 Buy
TRC B694050 8-tert-Butyloxycarbonylamino-3,6-dioxaoctanoicAcid 108466-89-3 2.5g $1260 2021-12-16 Buy
Iris Biotech GmbH PEG8080 Boc-O2Oc 108466-89-3 25g $1350 2021-12-16 Buy
ChemPep 280209 Boc-AEEA 108466-89-3 5g $250 2021-12-16 Buy
Apolloscientific BIPG1825 t-Boc-N-amido-PEG2-CH2CO2H 108466-89-3 5g $540 2021-12-16 Buy
Product number Packaging Price Buy
901577 50MG $34.4 Buy
B694050 2.5g $1260 Buy
PEG8080 25g $1350 Buy
280209 5g $250 Buy
BIPG1825 5g $540 Buy

3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Chemical Properties,Uses,Production

Description

t-Boc-N-amido-PEG2-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

24424-99-5
105-36-2
929-06-6
108466-89-3
Synthesis of 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- from Di-tert-butyl dicarbonate and Ethyl bromoacetate and 2-(2-Aminoethoxy)ethanol
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View Lastest Price from 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid pictures 2019-07-06 2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid
108466-89-3
US $1.00 / KG 1KG 98% 100KG Career Henan Chemical Co
Boc-N-amido-PEG2-CH2CO2H t-boc-N-amido-PEG2-acetic acid 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- 8-tert-butyloxycarbonylaMino-3,6-dioxaoctanoic acid t-Boc-N-amido-PEG2-CH2CO2H BocNH-PEG2-CH2COOH T-BOC-NH-AMIDO-PEG2-CH2CO2H 2-[2-[2-(Boc-amino)ethoxy]ethoxy]acetic Acid 2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]acetic acid 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo- 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- USP/EP/BP 11-Trioxa-5-azatridecan-13-oic acid 2-diMethyl-4-oxo- 2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid 2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid Boc-AEEA-OH NHBoc-PEG2-CH2COOH t-Boc-N-Amido-PEG2-CH2COOH N-Boc-8-amino-3,6-dioxaoctanoic acid Boc-O 2 Oc-OH 2-[2-(2-([(tert-butoxy)carbonylaminoJethoxy)ethoxylacetic acid 2,2-dimethyl-4,13-dioxo-3,8,11-trioxa-5-azatetradecan-14-oic acid 108466-89-3 137978-97-5 peg