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Tivozanib

Tivozanib structure

CAS No.: 682745-41-1

Chemical Name:: Tivozanib

Synonyms: Tivozanib hydrochloride;Tivozanib hydrochloride hydrate;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea;N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea monohydrochloride monohydrate

CBNumber:: CB02651167

Molecular Formula:: C22H22Cl2N4O6

Molecular Weight:: 509.34

MDL Number:: MFCD34184484

MOL File:: 682745-41-1.mol

MSDS File:: SDS

Last updated:2023-05-21 10:59:17

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Tivozanib Properties

storage temp.	4°C, away from moisture and light
solubility	DMSO : 250 mg/mL (490.83 mM; Need ultrasonic)
FDA UNII	8A9H4VK35Z
NCI Drug Dictionary	tivozanib hydrochloride

Tivozanib Chemical Properties,Uses,Production

Uses

Tivozanib also known as AV-951 is an orally bioavailable potent VEGFR-1, 2 and 3, c-Kit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM, respectively.

Tivozanib Preparation Products And Raw materials

Raw materials

Preparation Products

Tivozanib Suppliers

Global( 18)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Guangzhou TongYi biochemistry technology Co.,LTD	+8613073028829	mack@tongyon.com	China	2996	58
Beijing Mesochem Technology Co.,Ltd	+8613651027935	rachel@mesochem.com	China	191	58
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811783	sales@trio-pharmatech.com (International market)	China	1856	62
Shanghai Hope Chem Co., Ltd.，	+21-18501659228 18501659228	info@hope-chem.com	China	433	55
Shanghai AECOM Biotechnology Co. , Ltd.	021-021-20956531 18116226605	sui@neosunpharm.com	China	350	55
Raw material medicin reagent co.,Ltd	025-57798860	sales@njromanme.com	China	4534	58
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8012	62
WuHu Linze pharmaceutical Co.,Ltd.	0553-0553-5802116 18356571950	2592492800@qq.com	China	58	58
Beijing Mesochem Technology Co., Ltd.	010-57862036 18811083386	msales@mesochem.com	China	190	58

Supplier	Advantage
Career Henan Chemica Co	58
Guangzhou TongYi biochemistry technology Co.,LTD	58
Beijing Mesochem Technology Co.,Ltd	58
Jinan Trio PharmaTech Co., Ltd.	62
Shanghai Hope Chem Co., Ltd.，	55
Shanghai AECOM Biotechnology Co. , Ltd.	55
Raw material medicin reagent co.,Ltd	58
ShangHai Biochempartner Co.,Ltd	62
WuHu Linze pharmaceutical Co.,Ltd.	58
Beijing Mesochem Technology Co., Ltd.	58

1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea monohydrochloride monohydrate Tivozanib hydrochloride Tivozanib hydrochloride hydrate 682745-41-1 C22H22Cl2N4O6