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Methyl gallate

CAS No.
99-24-1
Chemical Name:
Methyl gallate
Synonyms
METHYL 3,4,5-TRIHYDROXYBENZOATE;GALLIC ACID METHYL ESTER;GALLICIN;Gallincin;methyl galloate;NSC 363001;AKOS 217-13;METHYGALLATE;METHYL GALLATE;MethylGallate>
CBNumber:
CB0265566
Molecular Formula:
C8H8O5
Molecular Weight:
184.15
MDL Number:
MFCD00002194
MOL File:
99-24-1.mol
MSDS File:
SDS
Last updated:2024-03-20 19:26:33

Methyl gallate Properties

Melting point 201-204 °C
Boiling point 278.08°C (rough estimate)
Density 1.3840 (rough estimate)
refractive index 1.5690 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility ethanol: 50 mg/mL, clear
form Crystalline Powder
pka 8.04±0.23(Predicted)
color White to slightly beige
Water Solubility SOLUBLE IN HOT WATER
Merck 14,4345
BRN 2113180
InChIKey FBSFWRHWHYMIOG-UHFFFAOYSA-N
LogP 0.860
CAS DataBase Reference 99-24-1(CAS DataBase Reference)
FDA UNII 623D3XG80C
EPA Substance Registry System Benzoic acid, 3,4,5-trihydroxy-, methyl ester (99-24-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P301+P312+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-43
Safety Statements  26-36/37-24/25
WGK Germany  3
RTECS  LW8000000
TSCA  Yes
HS Code  29182900
NFPA 704
1
2 0

Methyl gallate price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 274194 Methyl 3,4,5-trihydroxybenzoate 98% 99-24-1 5g $25.86 2024-03-01 Buy
Sigma-Aldrich 274194 Methyl 3,4,5-trihydroxybenzoate 98% 99-24-1 100g $105 2024-03-01 Buy
TCI Chemical G0017 Methyl Gallate >98.0%(GC)(T) 99-24-1 25g $25 2024-03-01 Buy
TCI Chemical G0017 Methyl Gallate >98.0%(GC)(T) 99-24-1 100g $77 2024-03-01 Buy
Alfa Aesar L05926 Methyl 3,4,5-trihydroxybenzoate, 98% 99-24-1 50g $48.65 2024-03-01 Buy
Product number Packaging Price Buy
274194 5g $25.86 Buy
274194 100g $105 Buy
G0017 25g $25 Buy
G0017 100g $77 Buy
L05926 50g $48.65 Buy

Methyl gallate Chemical Properties,Uses,Production

Description

Methyl gallate is a phenol that has been found in Meliaceae and has diverse biological activities. It reduces adipogenic hormonal stimulation-induced lipid accumulation in 3T3-L1 cells when used at a concentration of 50 μM. Methyl gallate is active against V. cholerae in vitro (MIC = 32 μg/ml) and reduces V. cholerae-induced intestinal fluid accumulation in suckling mice when administered at doses of 50, 100, and 200 mg/kg. It reduces tumor growth and decreases the number of intratumor CD25+Foxp3high regulatory T cells (Tregs) in an EL-4 model of murine lymphoma. Methyl gallate (0.7, 7, and 70 mg/kg) reduces knee joint edema and leukocyte, neutrophil, and mononuclear cell infiltration in a mouse model of zymosan-induced arthritis.

Description

Methyl gallate is a phenolic compound found in Terminalia myriocarpa and Geranium niveum. It is also found in wine.
It is the methyl ester of gallic acid.

Chemical Properties

white to slightly beige crystalline powder

Uses

Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.

Uses

Methyl 3,4,5-trihydroxybenzoate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.

Uses

The gallate ester methyl gallate is used as an antioxidant. A ease was reported using a reprography paper.

Definition

ChEBI: Methyl 3,4,5-trihydroxybenzoate is a gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties. It has a role as a plant metabolite, an anti-inflammatory agent and an antioxidant.

Contact allergens

This ester of gallic acid is used as an antioxidant agent. A case was reported by using a reprography paper.

Purification Methods

Methyl gallate [99-24-1] M 184.2, m 202o. Crystallise the gallate ester from MeOH. [Beilstein 10 IV 1998.]

67-56-1
149-91-7
99-24-1
Synthesis of Methyl gallate from Methanol and Gallic acid
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View Lastest Price from Methyl gallate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl gallate pictures 2024-03-28 Methyl gallate
99-24-1
US $30.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
Methyl gallate pictures 2024-03-28 Methyl gallate
99-24-1
US $5.00 / kg 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
Methyl gallate pictures 2023-08-22 Methyl gallate
99-24-1
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
  • Methyl gallate pictures
  • Methyl gallate
    99-24-1
  • US $30.00 / kg
  • 99%
  • hebei hongtan Biotechnology Co., Ltd
  • Methyl gallate pictures
  • Methyl gallate
    99-24-1
  • US $5.00 / kg
  • ≥99%
  • Jinan Finer Chemical Co., Ltd
  • Methyl gallate pictures
  • Methyl gallate
    99-24-1
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
3,4,5-trihydroxybenzoic acid methyl ester (intermediate of bifendate) METHYL GALLATE(METHYL 3,4,5-TRIHYDROXYBENZOATE ) METHYLGALLATE(RG) 2-diazo-1-naphthol-5-sulfonic acid, ester with novolac METHYGALLATE 3,4,5-trihydroxy-benzoic acidd methyl ester METHYL 3,4,5-TRIHYDROXYBENZOATE / METHYL GALLATE Gallic acid methyl ester, Methyl 3,4,5-trihydroxybenzoate Benzoic acid, 3,4,5-trihydroxy, methyl ester Methyl 3,4,5-trihydroxybenzoate, 99 % (3aS,10E)-3aβ,4,5,6,7,8,9,11aα-Octahydro-7α-hydroxy-6-methylene-3β,10-dimethylcyclodeca[b]furan-2(3H)-one thyl 3,4,5-trihydroxybenzoate METHYL GALLATE 3,4,5-TRIHYDROXYBENZOIC ACID METHYL ESTER AKOS 217-13 Methyl 3,4,5-trihydroxybenzoate, 99% 50GR Methyl 3,4,5-trihydroxybenzoate, 99% 5GR RARECHEM AL BF 0070 3,4,5-trihydroxy-benzoicacimethylester Methyl 3,4,5-trihydroxybenzoate 98% Methyl 3,4,5-trihydroxybenzoate, 98.0%(GC&T Methyl Gallate≥98% Methyle3, 4, 5-trihydroxybenzoate Methyl gallate 99-24-1 Methyl 3,4,5-trihydroxybenzoate Methyl 3,4,5-trihydroxybenzoate 99-24-1 Methyl gallate MethylGallate> NSC 363001 Methyl Gallate ( Methyl 3,4,5-Trihydroxy Benzoate -98%) Methyl gallate (Gallincin METHYL 3,4,5-TRIHYDROXYBENZOATE GALLIC ACID METHYL ESTER GALLICIN methyl galloate Gallincin 99-24-1 99-54-1 HO3C6H2COOCH3 HO3C6H2CO2CH3 Alphabetic Analytical Chromatography Product Catalog Analytical Standards META - METH Food additive ,Antioxidant anticorrosive (intermediate of bifendate) Aromatic Esters Organic acids Photo Active Compounds