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(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate

CAS No.
1714114-25-6
Chemical Name:
(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate
Synonyms
D-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester;(S)-Isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate (sofosbuvir Impurity)
CBNumber:
CB02715788
Molecular Formula:
C18H17F5NO5P
Molecular Weight:
453.3
MDL Number:
MOL File:
1714114-25-6.mol

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate Properties

Boiling point 442.6±55.0 °C(Predicted)
Density 1.405±0.06 g/cm3(Predicted)
pka -3.81±0.70(Predicted)

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P270360 N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine1-MethylethylEster 1714114-25-6 25mg $1260 2021-12-16 Buy
ChemScene CS-B0822 (R)-isopropyl2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate 1714114-25-6 5mg $2500 2021-12-16 Buy
Product number Packaging Price Buy
P270360 25mg $1260 Buy
CS-B0822 5mg $2500 Buy

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate Chemical Properties,Uses,Production

Uses

N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine 1-Methylethyl Ester is an impurity of PSI-7977 (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11927 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17993 56
Shanghai XingTai Pharmaceutical Technology co., LTD 15801747407 sales01@suntechpharma.com China 123 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 7934 55
Jiaxing Deyi Chemical Co., Ltd. 0573-86-0573-85866609 13325730825 945717149@qq.com China 7960 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55936 58
Taizhou Nanfeng Pharmaceutical Research Institute 12345678910 nanfengdrug@163.com China 15323 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 18502726233 3641133981@qq.com China 9341 58
D-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester (S)-Isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate (sofosbuvir Impurity) 1714114-25-6