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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2

CAS No.
689284-12-6
Chemical Name:
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
Synonyms
TAPI-2 acetate salt;Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2;N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
CBNumber:
CB02750664
Molecular Formula:
C19H37N5O5
Molecular Weight:
415.53
MDL Number:
MFCD22581509
MOL File:
689284-12-6.mol
Last updated:2023-06-30 15:45:59

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Properties

storage temp. -20°C
form lyophilized solid
color white to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0420 TAPI-2 acetate salt ≥98% (HPLC) 689284-12-6 1mg $380 2024-03-01 Buy
TRC T731805 TAPI2 689284-12-6 1mg $265 2021-12-16 Buy
American Custom Chemicals Corporation INB0000229 TAPI-2 95.00% 689284-12-6 1MG $466.2 2021-12-16 Buy
Product number Packaging Price Buy
SML0420 1mg $380 Buy
T731805 1mg $265 Buy
INB0000229 1MG $466.2 Buy

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Chemical Properties,Uses,Production

Uses

TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers.

Biochem/physiol Actions

TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.

storage

Store at -20°C

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Preparation Products And Raw materials

Raw materials

Preparation Products

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7892 56
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
BOC Sciences -- info@bocsci.com USA 0 65
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4164 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide TAPI-2 acetate salt Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)- 689284-12-6