ChemicalBook >> CAS DataBase List >>2-Chlorocinnamic acid

2-Chlorocinnamic acid

CAS No.
3752-25-8
Chemical Name:
2-Chlorocinnamic acid
Synonyms
AKOS BBB/195;AKOS B004073;AKOS BBS-00006452;Chlorocinnamicacid;RARECHEM BK HC T319;2-Chlorocinnamicaci;o-chloro-cinnamicaci;2-CLOROCINNAMIC ACID;O-CHLOROCINNAMIC ACID;OTAVA-BB BB0125160239
CBNumber:
CB0278409
Molecular Formula:
C9H7ClO2
Molecular Weight:
182.6
MDL Number:
MFCD00004372
MOL File:
3752-25-8.mol
MSDS File:
SDS
Last updated:2024-04-22 15:59:48

2-Chlorocinnamic acid Properties

Melting point 208-210 °C(lit.)
Boiling point 260.71°C (rough estimate)
Density 1.2377 (rough estimate)
refractive index 1.5426 (estimate)
storage temp. Room temperature.
Water Solubility Insoluble in water
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder to crystal
pka 4.23(at 25℃)
color White to Almost white
BRN 1365198
InChIKey KJRRTHHNKJBVBO-AATRIKPKSA-N
CAS DataBase Reference 3752-25-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII LT5X82W7YR
NIST Chemistry Reference 2-Chlorocinnamic acid(3752-25-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS06
Signal word  Warning
Hazard statements  H302-H315-H319-H301-H335
Precautionary statements  P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-22
Safety Statements  36-26-36/37
WGK Germany  3
RTECS  GD8450000
Hazard Note  Irritant
HS Code  29124990
NFPA 704
1
2 0

2-Chlorocinnamic acid price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C0974 2-Chlorocinnamic Acid >98.0%(GC)(T) 3752-25-8 25g $36 2024-03-01 Buy
Alfa Aesar L01606 2-Chlorocinnamic acid, predominantly trans, 99% 3752-25-8 25g $38.3 2021-12-16 Buy
Alfa Aesar L01606 2-Chlorocinnamic acid, predominantly trans, 99% 3752-25-8 100g $100 2021-12-16 Buy
TRC C428250 (E)-3-(2-Chlorophenyl)acrylicacid 3752-25-8 2.5g $65 2021-12-16 Buy
TRC C428250 (E)-3-(2-Chlorophenyl)acrylicacid 3752-25-8 500mg $45 2021-12-16 Buy
Product number Packaging Price Buy
C0974 25g $36 Buy
L01606 25g $38.3 Buy
L01606 100g $100 Buy
C428250 2.5g $65 Buy
C428250 500mg $45 Buy

2-Chlorocinnamic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder. Insoluble in water, soluble in ethanol, ethyl acetate and other organic solvents.

Uses

2-Chlorocinnamic acid is a kind of trans-cinnamate. It is used in organic synthesis.

Biological Functions

2-Chlorocinnamic acid is a cinnamic acid derivative that inhibits the hydroxylation of phenylpropanoids. It has been shown to inhibit the activity of cinnamic acid derivatives and their hydroxylation in cell lines, which is linked to the inhibition of cellulose acetate synthesis. 2-Chlorocinnamic acid also has an inhibitory effect on the chloride ion and water molecule. The chloride ion may be needed for the formation of hydrochloric acid, which is necessary for cellulose acetate hydrolysis, while water molecules are involved in many biochemical reactions. 2-Chlorocinnamic acid affects human cell lines at temperatures between 10°C and 37°C and at regiospecific sites. This oxidative dehalogenation reaction catalyzed by R. rubra was found to be regiospecific for 2-chlorocinnamic acid; the chloride ion was probably removed after the ring fission reaction.

Synthesis

O-chlorocinnamic acid is prepared by reacting o-phthalaldehyde with malonic acid.

2-Chlorocinnamic acid Preparation Products And Raw materials

Global( 326)Suppliers
Supplier Tel Email Country ProdList Advantage
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7534 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8822 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58

View Lastest Price from 2-Chlorocinnamic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chlorocinnamic acid pictures 2024-04-22 2-Chlorocinnamic acid
3752-25-8
US $32.00-1.10 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2-Chlorocinnamic acid pictures 2023-09-07 2-Chlorocinnamic acid
3752-25-8
US $30.00 / KG 1KG 99% 1000t/year Anhui Ruihan Technology Co., Ltd
2-Chlorocinnamic acid pictures 2023-06-09 2-Chlorocinnamic acid
3752-25-8
US $0.00-0.00 / kg 1kg 99% 500000kg Hebei Yibangte Import and Export Co. , Ltd.
AKOS BBS-00006452 AKOS B004073 AKOS BBB/195 3-(2-CHLOROPHENYL)PROPENOIC ACID 3-(2-CHLORO-PHENYL)-ACRYLIC ACID RARECHEM BK HC T319 OTAVA-BB BB0125160239 O-CHLOROCINNAMIC ACID (2E)-3-(2-Chlorophenyl)-2-propenoic acid 2-Propenoic acid, 3-(2-chlorophenyl)- 3-(2-chlorophenyl)-2-propenoicaci (2E)-3-(2-CHLOROPHENYL)ACRYLIC ACID 2-CHLOROCINNAMIC ACID 3-(2-chlorophenyl)-2-propenoicacid Cinnamic acid, o-chloro- o-chloro-cinnamicaci 2-Chlorocinnamic acid, predominantly trans Chlorocinnamicacid 2-CHLOROCINNAMIC ACID, 99%, PREDOMINANTL Y TRANS 2-CLOROCINNAMIC ACID 2-Chlorocinnamic acid, predominantly trans, 99.50% ORTHO-CHLOROCINNAMICACID 2-CHLOROCINNAMIC ACID, 99.50%, PREDOMINANTLY TRANS o-chlorocinnamic acid(2- (E)-3-(2-Chlorophenyl)acrylic acid 2-Chlorocyciamic acid 3-(2-Chlorophenyl)acrylic acid, 3-(2-Chlorophenyl)prop-2-enoic acid 2-ChlorocycinnaMic acid (E)-3-(2-chlorophenyl)-2-propenoate 3-(2-chlorophenyl)prop-2-enoic acid 2-Chlorocinnamic Acid > 2-Chlorocinnamicaci 2-Chlorocinnamic acid USP/EP/BP 2-Chloro cinnamic acid,o-chloro-cinnamicaci,Chlorocinnamicacid,O-CHLOROCINNAMIC ACID,2-CLOROCINNAMIC ACID,2-ChlorocinnaMic 2-Chlorocinnamic acid-99% 3752-25-8 C9H7ClO2 2-Chlorocinnamic acid 3752-25-8 C6H5CHCClCOOH C9H5CIO2 C9H6ClO2 Organic Building Blocks Building Blocks C9 Carboxylic Acids Carbonyl Compounds CARBOXYLIC ACID Aromatic Cinnamic Acids, Esters and Derivatives Cinnamic acid Acids & Esters Chlorine Compounds 3752-25-8