ChemicalBook >> CAS DataBase List >>Hs 27

Hs 27

Hs 27 structure

CAS No.: 1562024-11-6

Chemical Name:: Hs 27

Synonyms: Hs 27;HS27,HS 27;1562024-11-7;HS27;HS-27;HS 27;2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thio,HS-27;2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27;2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27;Benzamide, 2-[[21-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-21-thioxo-4,7,10,13,16-pentaoxa-20-azaheneicos-1-yl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indazol-1-yl)-

CBNumber:: CB02984841

Molecular Formula:: C52H60N6O12S

Molecular Weight:: 993.13

MDL Number:: MFCD32173434

MOL File:: 1562024-11-6.mol

Last updated:2023-09-04 15:51:00

Request For Quotation

Hs 27 Properties

Boiling point	1095.1±75.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	-196°C
solubility	DMSO: 125 mg/mL (125.86 mM)
pka	9.33±0.20(Predicted)

Hs 27 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0114853	HS-27 98.48%	1562024-11-6	5mg	$350	2021-12-16	Buy
ChemScene	CS-0114853	HS-27 98.48%	1562024-11-6	10mg	$580	2021-12-16	Buy
ChemScene	CS-0114853	HS-27 98.48%	1562024-11-6	25mg	$1100	2021-12-16	Buy
ChemScene	CS-0114853	HS-27 98.48%	1562024-11-6	50mg	$1700	2021-12-16	Buy
ChemScene	CS-0114853	HS-27 98.48%	1562024-11-6	100mg	$2500	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0114853	5mg	$350	Buy
CS-0114853	10mg	$580	Buy
CS-0114853	25mg	$1100	Buy
CS-0114853	50mg	$1700	Buy
CS-0114853	100mg	$2500	Buy

Hs 27 Chemical Properties,Uses,Production

Biological Activity

HS-27, a fluorescent Hsp90 inhibitor, detects Hsp90 expression on the surface of intact tissue specimens. It consists of the core elements of SNX-5422, an Hsp90 inhibitor linked via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC) that binds to peripherally expressed Hsp90 combine.

in vitro

HS-27 labels all receptor subtypes of breast cancer, but not normal cells, and specifically binds to Hsp90 expressed on the surface of breast cancer cells before being internalized.

target

HSP90

Hs 27 Preparation Products And Raw materials

Raw materials

Preparation Products

Hs 27 Suppliers

Global( 27)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2255	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4691	58
ZHIWE CHEMTECH CO LTD	021-20221225 13917446399	sales@zhiwe.net	China	577	61
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9833	58
Zhengzhou Huiju Chemical Co., Ltd.	0371-55900031 18137872243	2853979815@qq.com	China	10016	55
Heze Development Zone chuangli Chemical Co., Ltd.	+86-530-529 6766，+86-15666160102 15666160102	info@chuangli-chem.com	China	869	55
Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.	029-87576359 17691182729	1018@dideu.com	China	1985	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Xi'an MC Biotech, Co., Ltd.	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
ZHIWE CHEMTECH CO LTD	61
Shanghai Chaolan Chemical Technology Center	58
Zhengzhou Huiju Chemical Co., Ltd.	55
Heze Development Zone chuangli Chemical Co., Ltd.	55
Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.	58

Hs 27 Spectrum

Hs 27(1562024-11-6)¹HNMR

Hs 27 1562024-11-7 2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thio,HS-27 Benzamide, 2-[[21-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-21-thioxo-4,7,10,13,16-pentaoxa-20-azaheneicos-1-yl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indazol-1-yl)- HS27;HS-27;HS 27 2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27 HS27,HS 27 2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27 1562024-11-6 C52H60N6O12S