ChemicalBook >> CAS DataBase List >>4-Ethylresorcinol

4-Ethylresorcinol

CAS No.
2896-60-8
Chemical Name:
4-Ethylresorcinol
Synonyms
KO 11;4-Ethyl Resorcin;5-Ethylresorcinol;4-ETHYLRESORCINOL;6-Ethylresorcinol;Resorcinol, 4-ethyl-;Ethyl 1,3-benzenediol;4-ethyl-3-benzenediol;4-Ethylresorcinol,98%;4-Ethylresorcinol 98%
CBNumber:
CB0300724
Molecular Formula:
C8H10O2
Molecular Weight:
138.16
MDL Number:
MFCD00002283
MOL File:
2896-60-8.mol
MSDS File:
SDS
Last updated:2024-03-22 17:13:11

4-Ethylresorcinol Properties

Melting point 95-98 °C (lit.)
Boiling point 155 °C / 10mmHg
Density 1.0742 (rough estimate)
refractive index 1.5231 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Solubility in methanol; almost transparency. Soluble in alcohol.
form Crystalline Powder
pka 10.06±0.10(Predicted)
color Slightly beige
BRN 1238231
InChIKey VGMJYYDKPUPTID-UHFFFAOYSA-N
LogP 1.731 (est)
CAS DataBase Reference 2896-60-8(CAS DataBase Reference)
FDA UNII 8YE81T06D5
NIST Chemistry Reference 1,3-Benzenediol, 4-ethyl-(2896-60-8)
EPA Substance Registry System 4-Ethylresorcinol (2896-60-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36
WGK Germany  3
TSCA  Yes
HS Code  29072100
NFPA 704
1
2 0

4-Ethylresorcinol price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E48200 4-Ethylresorcinol 98% 2896-60-8 25g $412 2024-03-01 Buy
TCI Chemical D0579 4-Ethylresorcinol >98.0%(GC) 2896-60-8 5g $55 2024-03-01 Buy
TCI Chemical D0579 4-Ethylresorcinol >98.0%(GC) 2896-60-8 25g $149 2024-03-01 Buy
Alfa Aesar B21575 4-Ethylresorcinol, 98% 2896-60-8 5g $53.65 2024-03-01 Buy
Alfa Aesar B21575 4-Ethylresorcinol, 98% 2896-60-8 25g $167.65 2024-03-01 Buy
Product number Packaging Price Buy
E48200 25g $412 Buy
D0579 5g $55 Buy
D0579 25g $149 Buy
B21575 5g $53.65 Buy
B21575 25g $167.65 Buy

4-Ethylresorcinol Chemical Properties,Uses,Production

Description

4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol has hypopigmentation effects.4-Ethylresorcinol attenuates the mRNA and protein expression of tyrosinase-related protein (TRP)-2, and has an antioxidant effect through the inhibition of lipid peroxidation. 4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol is a derivative of resorcinol.

Chemical Properties

slightly beige crystalline powder

Uses

It is employed as an active pharmaceutical intermediate.

Definition

ChEBI: 4-Ethylresorcinol is a member of resorcinols.

Synthesis Reference(s)

Synthetic Communications, 15, p. 1315, 1985 DOI: 10.1080/00397918508077280

Synthesis

The synthesis of 4-Ethylresorcinol is as follows:
In a three necked round bottom flask (equipped with a condensor, additional funnel and mechanical stirrer) was added 15.2 g of a combination of Raney Nickel and Ni supported on silica. (50: 50). 100 ml of a mixture of 50: 50 ethanol: water was added and the reaction was heated at reflux conditions. 15.2 g of 2,4-dihydroxy acetophenone in 100 ml of water: ethanol and 10 ml of acetic acid was placed in the additional funnel and slowly added to the mixture (dropwise). The reaction was filtered through a milipore filter to give a pale yellow solution. Concentration of this solution in vacuo gave a solid. This solid was crystalized from 1,2-dichloroethane to give 4-ethyl resorcinol in 80% isolated yield. 
synthesis of 4-Ethylresorcinol.png

89-84-9
2896-60-8
Synthesis of 4-Ethylresorcinol from 2,4-Dihydroxyacetophenone
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View Lastest Price from 4-Ethylresorcinol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Ethylresorcinol pictures 2024-04-24 4-Ethylresorcinol
2896-60-8
US $0.00-0.00 / kg 0.10000000149011612kg 99% 20tons Chongqing Zhihe Biopharmaceutical Co., Ltd.
4-Ethylresorcinol pictures 2023-08-18 4-Ethylresorcinol
2896-60-8
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
4-Ethylresorcinol pictures 2022-11-16 4-Ethylresorcinol
2896-60-8
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Guanlang Biotechnology Co., Ltd.
  • 4-Ethylresorcinol pictures
  • 4-Ethylresorcinol
    2896-60-8
  • US $0.00-0.00 / kg
  • 99%
  • Chongqing Zhihe Biopharmaceutical Co., Ltd.
  • 4-Ethylresorcinol pictures
  • 4-Ethylresorcinol
    2896-60-8
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
1,3-Dihydroxy-4-ethylbenzene 4-ethyl-3-benzenediol 6-Ethylresorcinol Ethyl 1,3-benzenediol Resorcinol, 4-ethyl- 2,4-dihydroxy-1-ethylbenzene 2,4-DIHYDROXYETHYLBENZENE 4-ETHYL-1,3-BENZENEDIOL 4-ETHYLRESORCINOL 4-Ethyl Resorcin 5-Ethylresorcinol 1,3-DIHYDROXY-4-ETHYLBENZENE,97+% KO 11 5-Ethylresorcinol , (2,4-Dihydroxyl-1-ethylbenzene) 4-Ethylresorcinol,98% 4-Ethylresorcinol 98% 4-Ethylresorcinol > 1,3-Benzenediol, 4-ethyl- Flumazenil Impurity 21 2896-60-8 C2H5C6H313OH2 Building Blocks Polyols Oxygen Compounds Organic Building Blocks Building block Building Blocks Chemical Synthesis Organic Building Blocks Oxygen Compounds Polyols Aromatic Phenols API