ChemicalBook >> CAS DataBase List >>Paramethasone
Paramethasone
- CAS No.
- 53-33-8
- Chemical Name:
- Paramethasone
- Synonyms
- Cortiden;PARAMETHASONE;Picaridin Impurity 9;6a-Fluoro-16a-methylprednisolone;16a-Methyl-6a-fluoroprednisolone;6-alpha-fluoro-16-alpha-methylprednisolone;Methylprednisolone Impurity 30 (Paramethasone);1, 4-PREGNADIEN-6α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE;6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione;6a-fluoro-11b,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione
- CBNumber:
- CB0301372
- Molecular Formula:
- C22H29FO5
- Molecular Weight:
- 392.46
- MDL Number:
- MFCD03695621
- MOL File:
- 53-33-8.mol
Last updated:2023-05-04 17:34:39
| Melting point | 228-241°C |
|---|---|
| Boiling point | 573.5±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.34±0.70(Predicted) |
| color | White to Pale Beige |
| CAS DataBase Reference | 53-33-8 |
| FDA UNII | VFC6ZX3584 |
| ATC code | H02AB05 |
Paramethasone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P191840 | Paramethasone | 53-33-8 | 2.5mg | $185 | 2021-12-16 | Buy |
| TRC | P191840 | Paramethasone | 53-33-8 | 25mg | $1455 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 60958 | Paramethasone | 53-33-8 | 25mg | $2200 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007268 | PARAMETHASONE 95.00% | 53-33-8 | 5G | $909.56 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007268 | PARAMETHASONE 95.00% | 53-33-8 | 10G | $1334.03 | 2021-12-16 | Buy |
Paramethasone Chemical Properties,Uses,Production
Originator
Haldrone,Lilly,US,1961
Uses
Paramethasone, is a fluorinated glucocorticoid, having anti-inflammatory and immunosuppressant properties.
Uses
Glucocorticoid.
Definition
ChEBI: Paramethasone is a fluorinated steroid.
Manufacturing Process
A solution of 0.144 g of the 3-ethylene glycol ketal of 5α,11β,17α,21 tetrahydroxy-6β-fluoro-16α-methylallopregnane-3,20-dione-21 acetate in 12 ml of chloroform and 0.1 ml of absolute alcohol was cooled to -10°C in an icesalt bath and a stream of anhydrous hydrochloric acid was gently bubbled through the solution for 2.5 hours while the temperature was maintained between -5°C and -15°C. The solution was then diluted with 25 ml of chloroform, washed with dilute sodium bicarbonate and water, dried over anhydrous sodium sulfate, and evaporated to dryness under reduced pressure at 60°C or less to give 6α-fluoro-11β,17α,21-trihydroxy-16α-methyl-4-pregnene3,20-dione 21-acetate.
brand name
Haldrone (Lilly).
Therapeutic Function
Glucocorticoid
Paramethasone Preparation Products And Raw materials
Global( 48)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-020-82000279 18988968278 | sales@ubiochem.com | China | 2357 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2127 | 70 |
53-33-8(Paramethasone)Related Search:
1of4
16a-Methyl-6a-fluoroprednisolone
6a-Fluoro-16a-methylprednisolone
Cortiden
Pregna-1,4-diene-3,20-dione, 6a-fluoro-11b,17,21-trihydroxy-16a-methyl- (8CI)
Pregna-1,4-diene-3,20-dione, 6a-fluoro-11b,17,21-trihydroxy-16-methyl- (7CI)
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)- (9CI)
(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
PARAMETHASONE
6a-fluoro-11b,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione
6-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
6-alpha-fluoro-16-alpha-methylprednisolone
1,4-PREGNADIEN-6-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE
(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
6-fluoro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16α)-
Pregna-1,4-diene-3,20-dione,6-fluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-
Methylprednisolone Impurity 30 (Paramethasone)
Picaridin Impurity 9
1, 4-PREGNADIEN-6α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE
53-33-8