Adipotide
- CAS No.
- Chemical Name:
- Adipotide
- Synonyms
- FTPP;Adipotide
- CBNumber:
- CB03128839
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Adipotide Chemical Properties,Uses,Production
Description
AdipotideTM, or Prohibitin-Targeting Peptide 1 (Prohibitin-TP01), is an anti-obesity peptide that specifically targets and kills blood vessels supplying white fat tissue. It is the peptidomimetic CKGGRAKDC-GG-D(KLAKLAK)2. Adipotide targeted the vasculature of white adipose tissue and resulted in ~30% weight reduction in obese mice over a period of 4 weeks. Therefore, unlike nonspecific angiogenesis inhibitors, adipokine is systemically targeted to the endothelium of fat through a ligand-directed mechanism and disrupts the vascular supply of white adipose tissue, at least in rodent obesity models. Moreover, an annexin A2–prohibitin receptor system targeted by adipotide has been reported recently in the white adipose tissue vasculature of human patients[1].
References
[1] Kirstin F Barnhart. “A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.” Science Translational Medicine 3 108 (2011): 108ra112.
Adipotide Preparation Products And Raw materials
Raw materials
Preparation Products
Adipotide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 882 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1099 | 58 |
| Shijiazhuang Saixin Technology Co., Ltd. | +86-16632312509 +86-16632315022 | saixinkeji@aliyun.com | China | 90 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 952 | 58 |
| CONTIDE BIOTECH CO.,LTD | +852-53358525 | xena@healthtide-api.com | China | 619 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 2278 | 58 |
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 247 | 58 |
View Lastest Price from Adipotide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-05-27 | Adipotide | US $0.00 / G | 1G | 99% | 20 | CONTIDE BIOTECH CO.,LTD | |
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2024-05-27 | Adipotide | US $60.00-40.00 / box | 1box | 99.9% | 500 box | hebei hongtan Biotechnology Co., Ltd | |
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2024-05-27 | Adipotide | US $50.00-30.00 / box | 1box | 99.99% | 1000 | hebei hongtan Biotechnology Co., Ltd |