ChemicalBook >> CAS DataBase List >>(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

CAS No.
1422361-25-8
Chemical Name:
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
Synonyms
Emtricitabine Impurity 21;5-Fluoro-1-(2’-L-menthyloxycarbonyl-1’-3’-oxathiolan-5’-yl)-cytosine;(1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabine Uracil Carboxylate;(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester;1,3-Oxathiolane-2-carboxylic acid, 5-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2R,5S)-
CBNumber:
CB03139657
Molecular Formula:
C18H25FN2O5S
Molecular Weight:
400.46
MDL Number:
MOL File:
1422361-25-8.mol

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Properties

Density 1.32±0.1 g/cm3(Predicted)
pka 7.51±0.10(Predicted)

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I779120 (1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabineUracilCarboxylate 1422361-25-8 10mg $525 2021-12-16 Buy
Biosynth Carbosynth NF58425 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine 1422361-25-8 500mg $825 2021-12-16 Buy
Biosynth Carbosynth NF58425 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine 1422361-25-8 1g $1430 2021-12-16 Buy
Biosynth Carbosynth NF58425 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine 1422361-25-8 50mg $90.5 2021-12-16 Buy
Biosynth Carbosynth NF58425 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine 1422361-25-8 100mg $145 2021-12-16 Buy
Product number Packaging Price Buy
I779120 10mg $525 Buy
NF58425 500mg $825 Buy
NF58425 1g $1430 Buy
NF58425 50mg $90.5 Buy
NF58425 100mg $145 Buy

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Chemical Properties,Uses,Production

Uses

(1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabine Uracil Carboxylate is the uracil impurity of the parent compound Emtricitabine, E525000, which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Suppliers

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Standardpharm Co. Ltd.
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NewCan Biotech Limited
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Zhengzhou Convergence Chemical Co. LTD 0371-53736046 13393710386 2853979814@qq.com China 10003 58
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Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 sales@dmstandards.com China 10951 58
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabine Uracil Carboxylate Emtricitabine Impurity 21 5-Fluoro-1-(2’-L-menthyloxycarbonyl-1’-3’-oxathiolan-5’-yl)-cytosine 1,3-Oxathiolane-2-carboxylic acid, 5-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2R,5S)- 1422361-25-8