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6-HYDROXYDOPAMINE HYDROCHLORIDE

6-HYDROXYDOPAMINE HYDROCHLORIDE Structure
6-HYDROXYDOPAMINE HYDROCHLORIDE structure
CAS No.
28094-15-7
Chemical Name:
6-HYDROXYDOPAMINE HYDROCHLORIDE
Synonyms
6-OHDA;6-Hd HCl;Nsc233898;OxydopaMine HCL;TIMTEC-BB SBB003496;6-Hydroxydopamine hy;6-OHDA hydrochloride;TopaMine Hydrochloride;OxidopaMine Hydrochloride;6-hydroxydopaminechloride
CBNumber:
CB0320270
Molecular Formula:
C8H12ClNO3
Molecular Weight:
205.64
MDL Number:
MFCD00012895
MOL File:
28094-15-7.mol
Last updated:2023-09-28 17:55:30
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6-HYDROXYDOPAMINE HYDROCHLORIDE Properties

Melting point 232-233 °C (dec.)(lit.)
storage temp. room temp
solubility H2O: >50 mg/mL, clear, yellow to brown
form powder
color off-white to brown
BRN 4274007
InChI InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
InChIKey QLMRJHFAGVFUAC-UHFFFAOYSA-N
SMILES C1(CCN)=CC(=C(O)C=C1O)O.Cl
EWG's Food Scores 1
FDA UNII 9WBV30HXTL
EPA Substance Registry System 6-Hydroxydopamine hydrochloride (28094-15-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  DC4650000
F  3-8-10-23

6-HYDROXYDOPAMINE HYDROCHLORIDE price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H4381 6-Hydroxydopamine hydrochloride ≥97% (titration), powder 28094-15-7 100mg $144 2024-03-01 Buy
Sigma-Aldrich H4381 6-Hydroxydopamine hydrochloride ≥97% (titration), powder 28094-15-7 1g $850 2024-03-01 Buy
Sigma-Aldrich H4381 6-Hydroxydopamine hydrochloride ≥97% (titration), powder 28094-15-7 500mg $554 2024-03-01 Buy
TRC H941743 6-Hydroxydopamine hydrochloride 28094-15-7 10mg $55 2021-12-16 Buy
TRC H941743 6-Hydroxydopamine hydrochloride 28094-15-7 50mg $165 2021-12-16 Buy
Product number Packaging Price Buy
H4381 100mg $144 Buy
H4381 1g $850 Buy
H4381 500mg $554 Buy
H941743 10mg $55 Buy
H941743 50mg $165 Buy

6-HYDROXYDOPAMINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.

Uses

6-hydroxydopamine hydrochloride has been used:

  • to induce Parkinson′s disease (PD) in rats
  • to analyse cytotoxic effect of 6-OHDA on PC12 cell line
  • to induce noradrenergic (NA) neuron deletion from the locus-coeruleus

General Description

Beige solid.

Air & Water Reactions

Hygroscopic. Water soluble.

Reactivity Profile

A weak acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 6-HYDROXYDOPAMINE HYDROCHLORIDE emits very toxic fumes.

Fire Hazard

Flash point data for 6-HYDROXYDOPAMINE HYDROCHLORIDE are not available. 6-HYDROXYDOPAMINE HYDROCHLORIDE is probably combustible.

Biological Activity

Selective catecholaminergic neurotoxin. Depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease.

Biochem/physiol Actions

Neurotoxin that destroys catecholaminergic terminals.

6-HYDROXYDOPAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

6-HYDROXYDOPAMINE HYDROCHLORIDE Suppliers

Global( 99)Suppliers
Supplier Tel Email Country ProdList Advantage
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9571 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12453 58
Hebei Guanlang Biotechnology Co,.LTD 		+8619930503252 daisy@crovellbio.com China 5964 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 7838 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 12431 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503259 +86-19930503259 cherry@crovellbio.com China 18458 58
ZHEJIANG JIUZHOU CHEM CO., LTD 		+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com China 20000 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Supplier Advantage
Finetech Industry Limited
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Guanlang Biotechnology Co,.LTD 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
career henan chemical co 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
Hebei Guanlang Biotechnology Co., Ltd. 		58
ZHEJIANG JIUZHOU CHEM CO., LTD 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58

View Lastest Price from 6-HYDROXYDOPAMINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-HYDROXYDOPAMINE HYDROCHLORIDE pictures 2023-09-28 6-HYDROXYDOPAMINE HYDROCHLORIDE
28094-15-7
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
6-HYDROXYDOPAMINE HYDROCHLORIDE pictures 2023-07-14 6-HYDROXYDOPAMINE HYDROCHLORIDE
28094-15-7
 US $9.00 / KG 1KG 99.9 1 ton Hebei Guanlang Biotechnology Co,.LTD
6-HYDROXYDOPAMINE HYDROCHLORIDE pictures 2020-01-09 6-HYDROXYDOPAMINE HYDROCHLORIDE
28094-15-7
 US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

6-HYDROXYDOPAMINE HYDROCHLORIDE Spectrum

6-HYDROXYDOPAMINE HYDROCHLORIDE(28094-15-7)1HNMR6-HYDROXYDOPAMINE HYDROCHLORIDE(28094-15-7)Raman6-HYDROXYDOPAMINE HYDROCHLORIDE(28094-15-7)FT-IR6-HYDROXYDOPAMINE HYDROCHLORIDE(28094-15-7)IR

28094-15-7(6-HYDROXYDOPAMINE HYDROCHLORIDE)Related Search:

Dopamine hydrochloride Acetylcholine Ethylamine hydrochloride Tyramine hydrochloride DOPAMINE HYDROCHLORIDE
5-HYDROXYDOPAMINE HYDROCHLORIDE,5-HYDROXYDOPAMINE HYDROCHLORIDE 99% RARECHEM AN KB 1616 RARECHEM AN KB 0077 RARECHEM AN KD 0076 RARECHEM AN KD 0298
RARECHEM AN KD 0559 RARECHEM AN KD 1619 6-HYDROXYDOPAMINE HYDROCHLORIDE

1of3

4-(2-Aminoethyl)-1,2,3-benzenetriol hydrochloride 6-Hd HCl Nsc233898 OxidopaMine Hydrochloride 2,4,5-TrihydroxyphenethylamineHCl 2,4,5-Trihydroxyphenethylaminehydochloride 2,4,5-TRIHYDROXYPHENETHYLAMINEYDOCHLORIDE 2,4,5-Trihydroxyphenethylamine hydrochloride, 2,5-Dihydroxytyramine hydrochloride, 2-(2,4,5-Trihydroxyphenyl)ethylamine hydrochloride, 6-OHDA 1,2,3-Benzenetriol, 4-(2-aminoethyl)-, hydrochloride 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride 2,4,5-TRIHYDROXYPHENETHYLAMINE HYDROCHLORIDE 2,5-DIHYDROXYTYRAMINE HYDROCHLORIDE 2-(2,4,5-TRIHYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE TIMTEC-BB SBB003496 2,4-benzenetriol,5-(2-aminoethyl)-hydrochloride 5-(2-aminoethyl)-1,2,4-benzenetriolhydrochloride 6-hydroxydopaminechloride 5-(2-aminoethyl)-4-hydroxypyrocatechol hydrochloride TopaMine Hydrochloride 5-(2-aMinoethyl)benzene-1,2,4-triol hydrochloride OxydopaMine HCL 6-HYDROXYDOPAMINE HYDROCHLORIDE 6-Hydroxydopamine hy 6-OHDA hydrochloride 6-OHDA Neuro-2a cells,p-p38,Interleukin Related,p38 MAPK,PC12 cells,Apoptosis,Dopamine Receptor,Mitophagy,neurotoxicity,Autophagy,Oxidopamine hydrochloride,6-OHDA,Prostaglandin E synthase,Cyclooxygenase,Lesch-Nyhan syndrome,inhibit,Mitochondrial Autophagy,PGE2,attention-deficit hyperactivity disorder,Parkinson’s disease,SH-SY5Y cells,Oxidopamine,Caspase,PGE synthase,Inhibitor,COX,6-Hydroxydopamine 28094-15-7 HO3C6H2CH2CH2NH2HCl C8H11NO3ClH Amino Alcohols Building Blocks Oxygen Compounds Organic Building Blocks