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(R)-(+)-PROPRANOLOL

(R)-(+)-PROPRANOLOL structure

CAS No.: 13071-11-9

Chemical Name:: (R)-(+)-PROPRANOLOL

Synonyms: AY 20694;ICI 47319;R-PROPANOLOL;d-Anapriline;R-PROPRANOLOL;(+)-Anapriline;(R)-(+)-PROPRANOLOL;R-(+)-PROPANOLOL HCL;expropranololhydrochloride;d-Propranolol hydrochloride

CBNumber:: CB0327608

Molecular Formula:: C16H21NO2.ClH

Molecular Weight:: 295.81

MDL Number:: MFCD00064546

MOL File:: 13071-11-9.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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(R)-(+)-PROPRANOLOL Properties

Melting point	196-198 °C(lit.)
storage temp.	Store below +30°C.
solubility	ethanol: 10 mg/mL
form	Solid
color	White to Off-White
Water Solubility	Soluble to 100 mM in water
BRN	5780490
CAS DataBase Reference	13071-11-9(CAS DataBase Reference)
FDA UNII	AB9DB0NX46

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P501
Hazard Codes	Xn
Risk Statements	22
Safety Statements	22-24/25
WGK Germany	3
HS Code	2922 19 00

(R)-(+)-PROPRANOLOL price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P0689	(R)-(+)-Propranolol hydrochloride ≥98% (TLC)	13071-11-9	100mg	$106	2024-03-01	Buy
Sigma-Aldrich	P0689	(R)-(+)-Propranolol hydrochloride ≥98% (TLC)	13071-11-9	500mg	$424	2024-03-01	Buy
Tocris	0835	(R)-(+)-Propranolol hydrochloride	13071-11-9	100	$87	2021-12-16	Buy
TRC	P831790	(R)-(+)-Propranolol hydrochloride	13071-11-9	5g	$1190	2021-12-16	Buy
American Custom Chemicals Corporation	CCH0001748	R-PROPANOLOL 95.00%	13071-11-9	10G	$2425.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
P0689	100mg	$106	Buy
P0689	500mg	$424	Buy
0835	100	$87	Buy
P831790	5g	$1190	Buy
CCH0001748	10G	$2425.5	Buy

(R)-(+)-PROPRANOLOL Chemical Properties,Uses,Production

Description

(R)-Propranolol hydrochloride is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist with high affinity for β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.

Physical properties

(R)-Propranolol's solubility:ethanol: 10 mg/mLDMSO: <14.5 mg/mLH2O: 50 mg/mL (With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)

Uses

less active enantiomer

Uses

The R-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).

Biochem/physiol Actions

Less active enantiomer of propranolol.

Mechanism of action

Pronolol hydrochloride is a non-selective beta-receptor blocker that blocks beta receptors in the myocardium and has antagonistic effects on beta1 and beta2 receptors. Slow down the heart rate, inhibit cardiac contractility and conduction, reduce circulating blood volume, and reduce myocardial oxygen consumption.

storage

Store at RT

Purification Methods

The hydrochloride is recrystallised from n-PrOH or Me2CO. It is soluble in H2O and EtOH but is insoluble in Et2O, *C6H6 or EtOAc. The racemate has m 163-164o, and the free base recrystallises from cyclohexane with m 96o. [Howe & Shanks Nature 210 1336 1966.] The S-isomer (below) is the physiologically active isomer.

(R)-(+)-PROPRANOLOL Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-(+)-PROPRANOLOL Suppliers

Global( 97)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9821	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
TargetMol Chemicals Inc.	58
BOC Sciences	58
changzhou huayang technology co., ltd	58
LEAP CHEM CO., LTD.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Zibo Hangyu Biotechnology Development Co., Ltd	58

View Lastest Price from (R)-(+)-PROPRANOLOL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-12	(R)-(+)-PROPRANOLOL 13071-11-9	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
	2019-09-02	(R)-(+)-PROPRANOLOL 13071-11-9	US $1.00-1.00 / KG	1KG	98%	1lg; 2kg; 5kg; 10kg; 100kg	Career Henan Chemical Co

(R)-(+)-PROPRANOLOL
13071-11-9
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

(R)-(+)-PROPRANOLOL
13071-11-9
US $1.00-1.00 / KG
98%
Career Henan Chemical Co

(R)-(+)-PROPRANOLOL Spectrum

(R)-(+)-PROPRANOLOL(13071-11-9)MS (R)-(+)-PROPRANOLOL(13071-11-9)¹HNMR (R)-(+)-PROPRANOLOL(13071-11-9)IR1 (R)-(+)-PROPRANOLOL(13071-11-9)IR2 (R)-(+)-PROPRANOLOL(13071-11-9)Raman

13071-11-9((R)-(+)-PROPRANOLOL)Related Search:

(R)-4-Hydroxy Propranolol Hydrochloride,(S)-4-Hydroxy Propranolol Hydrochloride (R)-(+)-PROPRANOLOL PROPRANOLOL H+D409CL USP,DL-Propranolol hydrochloride, (±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride Propranolol Hydrochloride for pharmaceutical raw materials L-(-)-Propranolol hydrochloride,l-Propranolol chlorhydrate,l-Propranolol hydrochloride

Propanolol 4-Hydroxy Propranolol b-D-Glucuronide,4-Hydroxy Propranolol -D-Glucuronide rac Propranolol -D-Glucuronide Sodium Salt,propranolol glucuronide,rac Propranolol b-D-Glucuronide Sodium Salt (S)-4-Hydroxy Propranolol (+/-)-4Hydroxy Propranolol-d7 Sulfate

5-Hydroxy Propranolol-d5 rac 7-Hydroxy Propranolol O-isovaleryl propranolol (2S)-Propranolol,l-Propranolol Propranolol hydrochloride for performance test

(R)-4-Hydroxy Propranolol 4-HYDROXY PROPRANOLOL-D5 GLUCURONIDE rac 4-Hydroxy Propranolol-d7 -D-Glucuronide

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R-PROPANOLOL R-(+)-PROPANOLOL HCL 2R-(+)-Propanolol hydrochloride≥ 95% (GCMS) (R)-(+)-Propanolol hydrochloride for synthesis 2R-(+)-PROPANOLOL HYDROCHLORIDE 2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2R)- (+)-Anapriline 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride, (+)- (8CI) 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2R)- (9CI) 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (R)- AY 20694 d-Anapriline d-Propranolol hydrochloride ICI 47319 R-(+)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride (R)-(+)-PROPANOLOL HYDROCHLORIDE (R)-(+)-PROPRANOLOL R-PROPRANOLOL (R)-(+)-PROPRANOLOL HYDROCHLORIDE (R)-PROPRANOLOL HYDROCHLORIDE (R)-(+)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE (R)-(+)-1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE (R)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE Dexpropranolol hydrochloride (R)-(+)-Propranolol hydrochloride,(R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride (R)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride (R)-(+)-PROPANOLOL HYDROCHLORIDE 99+% (R)-1-(isopropylaMino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride (2R)-1-(1-naphthalenyloxy)-3-(propan-2-ylamino)-2-propanol hydrochloride (R)-(+)-PROPANOLOL HYDROCHLORIDE FOR SYN expropranololhydrochloride Inhibitor,enantiomer,Beta Receptor,(R)-Propranolol,Adrenergic Receptor,β-adrenoceptor,cardiac arrhythmias,(R)Propranolol hydrochloride,(R) Propranolol hydrochloride,inhibit Flumiclorac-pentyl Impurity 11 13071-11-9 C16H21NOSHCl C10H7OCH2CHOHCH2NHCHCH32HCl Organic Building Blocks Amino Alcohols Asymmetric Synthesis Chiral Building Blocks Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals