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ROSCOVITINE

ROSCOVITINE
ROSCOVITINE
CAS No.
186692-46-6
Chemical Name:
ROSCOVITINE
Synonyms
CYC 202;Posiphe;P34 CDC2;Roscovitin;Seliciclib;ROSCOVITINE;Roscoviline;(R)-2-(1-ETHY;(R)-ROSCOVITINE;ROSCOVITINE 95+%
CBNumber:
CB0367185
Molecular Formula:
C19H26N6O
Formula Weight:
354.45
MOL File:
186692-46-6.mol

ROSCOVITINE Properties

Density 
1.3
storage temp. 
−20°C
InChIKey
BTIHMVBBUGXLCJ-OAHLLOKOSA-N
CAS DataBase Reference
186692-46-6(CAS DataBase Reference)

SAFETY

Safety Statements  22-24/25
WGK Germany  3

ROSCOVITINE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 557360 Roscovitine 186692-46-6 1mg $50.5 2017-11-08 Buy
Sigma-Aldrich 557360 Roscovitine 186692-46-6 5mg $184 2017-11-08 Buy
Sigma-Aldrich R7772 Roscovitine ≥98% (TLC) 186692-46-6 5mg $283 2017-11-08 Buy
Sigma-Aldrich R7772 Roscovitine ≥98% (TLC) 186692-46-6 1mg $81.7 2017-11-08 Buy

ROSCOVITINE Chemical Properties,Uses,Production

Uses

Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.

Definition

ChEBI: 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.

ROSCOVITINE Preparation Products And Raw materials

Raw materials

Preparation Products


ROSCOVITINE Suppliers

Global( 114)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32767 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 756 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 10714 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885
021-65675885 info@efebio.com China 1998 58
skychemical Co.Ltd 021- 20917629 20958197
021-20960837 sales@skychemical.com China 2991 55
Angel Pharmatech, Ltd. +86 021-3875-5155
3358272972@qq.com China 2183 58
Shanghai Boyle Chemical Co., Ltd. 86-15221043597
86-21-57758967 sales@boylechem.com China 2921 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96817 76
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6093 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-50426030
86-021-50426522,50426273 sales@jingyan-chemical.com China 10089 60

186692-46-6(ROSCOVITINE)Related Search:


  • BioChemical
  • Apoptosis and Cell Cycle
  • 186692-46-6
  • 2-(R)-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
  • 2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
  • 6-BENZYLAMINO-2-(R)-[(1-ETHYL)-2-HYDROXYETHYLAMINO]-9-ISOPROPYLPURINE
  • ROSCOVITINE
  • (R)-ROSCOVITINE
  • (R)-2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
  • P34 CDC2
  • R-ROSCOVITINE 98% (HPLC)
  • ROSCOVITINE 95+%
  • 1-Butanol, 2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-, (2R)-
  • 2-(r)-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9h-purin-2-yl]amino]-1-butanol
  • Roscovitin
  • API intermediates
  • Seliciclib
  • 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
  • (2R)-2-[[6-(benzylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol
  • 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
  • Roscovitine (CYC202,Seliciclib)
  • 6-Benzylamino-2[(R)-(1'-ethyl-2'-hydroxyethylamino)]-9-isopropylpurine Roscovitine
  • Roscovitine,2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
  • Roscovitine(CYC202)
  • 2-[[9-(1-Methylethyl)-6-[(phenylMethyl)aMino]-9H-purin-2-yl]aMino]-
  • (R)-2-(1-ETHY
  • Roscovitine (Seliciclib)
  • (2R)-2-[[9-(1-Methylethyl)-6-[(phenylMethyl)aMino]-9H-purin-2-yl]aMino]-1-butanol
  • (R)-2-[[9-(1-Methylethyl)-6-[(phenylMethyl)aMino]-9H-purin-2-yl]aMino]-1-butanol
  • CYC 202
  • Apis
  • Roscovitine (Seliciclib,CYC202)
  • 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine Roscovitine
  • 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine Roscovitine (Seliciclib,CYC202)
  • Roscovitine (R)-Roscovitine
  • Roscovitine, >=98%
  • Inhibitors
  • Roscoviline
  • Posiphe
  • Cell Signaling and Neuroscience
  • Cell Cycle
  • Cell Cycle Regulators
  • Cell Biology
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