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ROSCOVITINE

ROSCOVITINE
ROSCOVITINE
CAS No.
186692-46-6
Chemical Name:
ROSCOVITINE
Synonyms
CYC 202;Posiphe;P34 CDC2;Roscovitin;Seliciclib;ROSCOVITINE;Roscoviline;(R)-2-(1-ETHY;(R)-ROSCOVITINE;ROSCOVITINE 95+%
CBNumber:
CB0367185
Molecular Formula:
C19H26N6O
Formula Weight:
354.45
MOL File:
186692-46-6.mol

ROSCOVITINE Properties

Density 
1.3
storage temp. 
−20°C
InChIKey
BTIHMVBBUGXLCJ-OAHLLOKOSA-N
CAS DataBase Reference
186692-46-6(CAS DataBase Reference)

SAFETY

Safety Statements  22-24/25
WGK Germany  3

ROSCOVITINE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 557360 Roscovitine 186692-46-6 1mg $50.5 2017-11-08 Buy
Sigma-Aldrich 557360 Roscovitine 186692-46-6 5mg $184 2017-11-08 Buy
Sigma-Aldrich R7772 Roscovitine ≥98% (TLC) 186692-46-6 5mg $283 2017-11-08 Buy
Sigma-Aldrich R7772 Roscovitine ≥98% (TLC) 186692-46-6 1mg $81.7 2017-11-08 Buy

ROSCOVITINE Chemical Properties,Uses,Production

Uses

Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.

Definition

ChEBI: 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.

ROSCOVITINE Preparation Products And Raw materials

Raw materials

Preparation Products


ROSCOVITINE Suppliers

Global( 105)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885
021-65675885 info@efebio.com China 1998 58
skychemical Co.Ltd 021- 20917629 20958197
021-20960837 sales@skychemical.com China 2995 55
Shanghai Boyle Chemical Co., Ltd. 86-15221043597
86-21-57758967 sales@boylechem.com China 2848 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96820 76
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6019 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-50426030
86-021-50426522,50426273 sales@jingyan-chemical.com China 10090 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501
+86-21-54096319 sales@sinch.com.cn China 11620 64
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418
001-617-206-9595 sales@chemreagents.com United States 9944 62
Chemfun Medical Technology(Shanghai) Co., Ltd. 021-67220633 & 021-37212706
+86-21-67220638 chemfun@chemfun.net China 21899 59
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1960 70

186692-46-6(ROSCOVITINE)Related Search:


  • BioChemical
  • Apoptosis and Cell Cycle
  • 186692-46-6
  • 2-(R)-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
  • 2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
  • 6-BENZYLAMINO-2-(R)-[(1-ETHYL)-2-HYDROXYETHYLAMINO]-9-ISOPROPYLPURINE
  • ROSCOVITINE
  • (R)-ROSCOVITINE
  • (R)-2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
  • P34 CDC2
  • R-ROSCOVITINE 98% (HPLC)
  • ROSCOVITINE 95+%
  • 1-Butanol, 2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-, (2R)-
  • 2-(r)-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9h-purin-2-yl]amino]-1-butanol
  • Roscovitin
  • API intermediates
  • Seliciclib
  • 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
  • (2R)-2-[[6-(benzylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol
  • 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
  • Roscovitine (CYC202,Seliciclib)
  • 6-Benzylamino-2[(R)-(1'-ethyl-2'-hydroxyethylamino)]-9-isopropylpurine Roscovitine
  • Roscovitine,2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
  • Roscovitine(CYC202)
  • 2-[[9-(1-Methylethyl)-6-[(phenylMethyl)aMino]-9H-purin-2-yl]aMino]-
  • (R)-2-(1-ETHY
  • Roscovitine (Seliciclib)
  • (2R)-2-[[9-(1-Methylethyl)-6-[(phenylMethyl)aMino]-9H-purin-2-yl]aMino]-1-butanol
  • (R)-2-[[9-(1-Methylethyl)-6-[(phenylMethyl)aMino]-9H-purin-2-yl]aMino]-1-butanol
  • CYC 202
  • Apis
  • Roscovitine (Seliciclib,CYC202)
  • 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine Roscovitine
  • 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine Roscovitine (Seliciclib,CYC202)
  • Roscovitine (R)-Roscovitine
  • Roscovitine, >=98%
  • Inhibitors
  • Roscoviline
  • Posiphe
  • Cell Signaling and Neuroscience
  • Cell Cycle
  • Cell Cycle Regulators
  • Cell Biology
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