ARTEMISININ
- CAS No.
- 491-54-3
- Chemical Name:
- ARTEMISININ
- Synonyms
- KAEMPFERIDE;ARTEANNUIN;ARTEMISIA ANNUA;kaempferid;ARTEANUIN;QINGHAOSA;Kaemperide;ARTEMISINE;Kempferide;CaMpheride
- CBNumber:
- CB0387974
- Molecular Formula:
- C16H12O6
- Molecular Weight:
- 300.26
- MDL Number:
- MFCD00016771
- MOL File:
- 491-54-3.mol
| Melting point | 156-157 °C(lit.) |
|---|---|
| Boiling point | 543.8±50.0 °C(Predicted) |
| Density | 1.538 |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat |
| pka | 6.32±0.40(Predicted) |
| color | Yellow |
| BRN | 305378 |
| LogP | 2.740 (est) |
| CAS DataBase Reference | 491-54-3 |
| FDA UNII | 508XL61MPD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 2 |
| RTECS | KD4170000 |
| HS Code | 29329990 |
ARTEMISININ price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 69545 | Kaempferide analytical standard | 491-54-3 | 10mg | $548 | 2024-03-01 | Buy |
| TCI Chemical | K0057 | Kaempferide >96.0%(GC) | 491-54-3 | 10mg | $129 | 2024-03-01 | Buy |
| TCI Chemical | K0057 | Kaempferide >96.0%(GC) | 491-54-3 | 50mg | $385 | 2024-03-01 | Buy |
| Cayman Chemical | 29673 | Kaempferide | 491-54-3 | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 29673 | Kaempferide | 491-54-3 | 10mg | $121 | 2024-03-01 | Buy |
ARTEMISININ Chemical Properties,Uses,Production
Chemical Properties
Yellow powder
Uses
Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumour possibilities. Impurity of Icaritin (I163700).
Definition
ChEBI: A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.
Biological Activity
the effects of phytoestrogens have been studied in the hypothalamic-pituitary-gonadal axis and various non-gonadal targets. epidemiologic and experimental evidence indicates a protective effect of phytoestrogens also in colorectal cancer. the mechanism through which estrogenic molecules control colorectal cancer tumorigenesis could possibly involve estrogen receptor β, which is the predominantly expressed estrogen receptor subtype in colon mucosa.
in vitro
kaempferide triglycoside proved to inhibit the proliferation of native and estrogen receptor β overexpressing colon cancer cells via a mechanism not mediated by ligand binding dependent estrogen receptor activation. it affected hct8 cell cycle progression through increasing the g0/g1 cell fraction and in estrogen receptor β overexpressing cells increased two antioxidant enzymes [1].
in vivo
the aim of one previous study was to evaluate the effect of kaempferol on tissue lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal cancer in male wistar rats and to compare its efficacy with irinotecan. this study revealed that kaempferol could be safely used as a chemopreventive agent in colorectal cancer [2].
References
[1] martineti v, tognarini i, azzari c, carbonell sala s, clematis f, dolci m, lanzotti v, tonelli f, brandi ml, curir p. inhibition of in vitro growth and arrest in the g0/g1 phase of hct8 line human colon cancer cells by kaempferide triglycoside from dianthus caryophyllus. phytother res. 2010 sep;24(9):1302-8.
[2] nirmala p, ramanathan m. effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. eur j pharmacol. 2011 mar 1;654(1):75-9.
ARTEMISININ Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
View Lastest Price from ARTEMISININ manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Kaempferide
491-54-3
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-06 | ARTEMISININ
491-54-3
|
US $302.00 / KG | 1KG | 99% | 1000kg | Career Henan Chemical Co |
-
- Kaempferide
491-54-3
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- ARTEMISININ
491-54-3
- US $302.00 / KG
- 99%
- Career Henan Chemical Co