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ChemicalBook >> CAS DataBase List >>(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Structure
(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE structure
CAS No.
71636-61-8
Chemical Name:
(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Synonyms
sk&f81297;(±)-6-Chloro-PB;SKF 81297 hydrobromi;SKF 81297 HYDROBROMIDE;(+/-)-SKF-81297 HYDROBROMIDE;(+/-)-6-CHLORO-PB HYDROBROMIDE;(+-)-6-CHLORO-PB HYDROBROMIDE (+-)-SKF-8 1297, HCL;6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;2,3,4,5-Tetrahydro-6-chloro-1-phenyl-1H-3-benzazepine-7,8-diol;6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol
CBNumber:
CB0491974
Molecular Formula:
C16H17BrClNO2
Molecular Weight:
370.67
MDL Number:
MFCD00153782
MOL File:
71636-61-8.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:41
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(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Properties

storage temp. Desiccate at +4°C
solubility H2O: 1.7 mg/mL
form solid
color gray
FDA UNII 9GBP09E08K

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-26-36
WGK Germany  3

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S143 (±)-6-Chloro-PB hydrobromide ≥98% (HPLC), solid 71636-61-8 25mg $271 2024-03-01 Buy
Sigma-Aldrich S143 (±)-6-Chloro-PB hydrobromide ≥98% (HPLC), solid 71636-61-8 100mg $803 2023-01-07 Buy
Tocris 1447 SKF81297hydrobromide ≥98%(HPLC) 71636-61-8 50 $901 2021-12-16 Buy
Tocris 1447 SKF81297hydrobromide ≥98%(HPLC) 71636-61-8 10 $215 2021-12-16 Buy
Usbiological 256680 SKF 81297 hydrobromide 71636-61-8 10mg $480 2021-12-16 Buy
Product number Packaging Price Buy
S143 25mg $271 Buy
S143 100mg $803 Buy
1447 50 $901 Buy
1447 10 $215 Buy
256680 10mg $480 Buy

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Uses,Production

Uses

(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal?regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats.

Definition

ChEBI: 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol is a benzazepine.

Biological Activity

Dopamine D 1 -like receptor agonist. Centrally active following systemic administration in vivo .

Biochem/physiol Actions

(+/-)-6-Chloro-PB HBr is a full D1 dopamine receptor agonist.

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 sales@szzxbio.com China 2949 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Sigma-Aldrich 80
EMMX Biotechnology LLC 60
Shanghai Universal Biotech Co.,Ltd 58
Suzhou Zhixin Biotechnology Co., Ltd. 58

71636-61-8((+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE)Related Search:

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE SKF 83959 HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE R(+)-6-CHLORO-7,8-DIHYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (R)-6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL BROMIDE
6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

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(+/-)-SKF-81297 HYDROBROMIDE (+/-)-6-CHLORO-PB HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE 6-CHLORO-2,3,4,5-TETRAHYDRO-1-PHENYL-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE SKF 81297 HYDROBROMIDE sk&f81297 (+-)-6-CHLORO-PB HYDROBROMIDE (+-)-SKF-8 1297, HCL 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepinehydrobromide 2,3,4,5-Tetrahydro-6-chloro-1-phenyl-1H-3-benzazepine-7,8-diol 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl- 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (±)-SKF-81297 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide (±)-6-Chloro-PB SKF 81297 hydrobromi 71636-61-8 C16H16ClNO2HBr Full D1 dopamine receptor agonist. Dopamine receptor