2-Aminobenzonitrile
- CAS No.
- 1885-29-6
- Chemical Name:
- 2-Aminobenzonitrile
- Synonyms
- ANTHRANILONITRILE;Aminobenzonitrile;2-CYANOANILINE;Benzonitrile, 2-amino-;AKOS 91125;2-CYANANILINE;O-CYANOANILINE;JACS-1885-29-6;O-aminonitrile;Anthranilonotrile
- CBNumber:
- CB0766038
- Molecular Formula:
- C7H6N2
- Molecular Weight:
- 118.14
- MDL Number:
- MFCD00007631
- MOL File:
- 1885-29-6.mol
- MSDS File:
- SDS
| Melting point | 45-48 °C (lit.) |
|---|---|
| Boiling point | 267-268 °C (lit.) |
| Density | 1.11 g/cm3 (50℃) |
| refractive index | 1.5500 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Crystalline Flakes |
| pka | 0.77(at 25℃) |
| color | Yellow to beige-brown |
| Water Solubility | INSOLUBLE |
| BRN | 907187 |
| InChIKey | HLCPWBZNUKCSBN-UHFFFAOYSA-N |
| LogP | 0.901 |
| CAS DataBase Reference | 1885-29-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 5RXH2B211R |
| NIST Chemistry Reference | Benzonitrile, 2-amino-(1885-29-6) |
| EPA Substance Registry System | Benzonitrile, 2-amino- (1885-29-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H317-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,T,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38-43 | |||||||||
| Safety Statements | 26-36/37-36 | |||||||||
| RIDADR | 3276 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CB4575000 | |||||||||
| TSCA | T | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269095 | |||||||||
| Toxicity | LD50 ivn-mus: 180 mg/kg CSLNX* NX#00381 | |||||||||
| NFPA 704 |
|
2-Aminobenzonitrile price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A89901 | 2-Aminobenzonitrile 98% | 1885-29-6 | 25g | $65.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | A89901 | 2-Aminobenzonitrile 98% | 1885-29-6 | 100g | $184 | 2024-03-01 | Buy |
| TCI Chemical | A0861 | 2-Aminobenzonitrile >98.0%(GC) | 1885-29-6 | 25g | $25 | 2024-03-01 | Buy |
| TCI Chemical | A0861 | 2-Aminobenzonitrile >98.0%(GC) | 1885-29-6 | 100g | $70 | 2024-03-01 | Buy |
| Alfa Aesar | A12286 | 2-Aminobenzonitrile, 98% | 1885-29-6 | 50g | $53.3 | 2024-03-01 | Buy |
2-Aminobenzonitrile Chemical Properties,Uses,Production
Chemical Properties
It is a chemically stable yellow solid that readily forms salts when it encounters acid. It can be oxidized to nitrogen oxide by oxidants but has certain toxicity. The substance is easily soluble in common organic solvents but hardly soluble in low-polarity solvents, and it is insoluble in water.
Uses
2-Aminobenzonitrile is used for induction of nitrilase activity in Arthrobacter and for radioprotective agent.
Preparation
Synthesis of 2-Aminobenzonitrile: 2-Aminobenzamide was dehydrated to 2-aminobenzonitrile without protection of the amino group in the presence of phenylphosphonyl dichloride and pyridine. The highest yield of 96% was obtained using reagent 2d, while reagents 2a-c yielded less than 60%.
The reagents used for the reaction included phosphoryl chloride (2a), phenyl phosphoryl dichloride (2b), 4-chlorophenyl phosphoryl dichloride (2c), and phenylphosphonic dichloride (2d) in pyridine.
synthesis of aminobenzonitrile by dehydration of aminobenzamide using phenylphosphonic dichloride in pyridine
Synthesis Reference(s)
Journal of the American Chemical Society, 96, p. 5933, 1974 DOI: 10.1021/ja00825a039
The Journal of Organic Chemistry, 43, p. 944, 1978 DOI: 10.1021/jo00399a030
Tetrahedron Letters, 32, p. 1007, 1991 DOI: 10.1016/S0040-4039(00)74473-X
Improving a process for the preparation of 2-aminobenzonitrile by reduction of 2-nitrobenzonitrile.
Safety Profile
Poison by intravenous route. Seealso NITRILES. When heated to decomposition it emitstoxic fumes of NOx and CN- .
2-Aminobenzonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xinchem Co., Ltd. | +86-021-34123252 +8618049800532 | xinchem@xinchem.com | China | 49 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3141 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 8095 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com | jocelynpan@zjarts.com | CHINA | 993 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from 2-Aminobenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-04-16 | 2-Aminobenzonitrile
1885-29-6
|
US $5.00-0.10 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2024-04-15 | 2-Aminobenzonitrile
1885-29-6
|
US $0.00-0.00 / kg | 1kg | 99% | 9999 | Zhengzhou Lingzhiyue Technology Co., Ltd | |
 |
2023-10-22 | 2-Aminobenzonitrile
1885-29-6
|
US $0.00-0.00 / drums | 1drums | 99%min. | 100tons | Shanghai Xinchem Co., Ltd. |
-
- 2-Aminobenzonitrile
1885-29-6
- US $5.00-0.10 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Aminobenzonitrile
1885-29-6
- US $0.00-0.00 / kg
- 99%
- Zhengzhou Lingzhiyue Technology Co., Ltd
-
- 2-Aminobenzonitrile
1885-29-6
- US $0.00-0.00 / drums
- 99%min.
- Shanghai Xinchem Co., Ltd.