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Fucoxanthin

CAS No.
3351-86-8
Chemical Name:
Fucoxanthin
Synonyms
Ccris 4055;Brn 0073179;Fucoxanthol;FUCOXANTHIN;Fuconxanthin(P);Fucoxanthin (10%);Fucoxanthin solution;all-trans-Fucoxanthin;(3S,3'S,5R,5'R,6S,6'R)-;Fucoxanthin DISCONTINUED
CBNumber:
CB0780168
Molecular Formula:
C42H58O6
Molecular Weight:
658.91
MDL Number:
MFCD01745140
MOL File:
3351-86-8.mol
MSDS File:
SDS
Last updated:2024-04-01 21:53:03

Fucoxanthin Properties

Melting point 166-168°C
alpha D18 +72.5 ±9° (chloroform)
Boiling point 590.43°C (rough estimate)
Density 1.09
refractive index n20/D1.360-1.362
Flash point 14℃
storage temp. -20°C
solubility Ethanol,
pka 14.47±0.60(Predicted)
color Crystalline
λmax λ: 444-454 nm Amax
InChIKey SJWWTRQNNRNTPU-WEAAWPSVSA-N
SMILES [C@]12(CC(=O)/C(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C=C3[C@@](O)(C)C[C@@H](OC(=O)C)CC3(C)C)C(C)(C)C[C@H](O)C[C@]1(O2)C |&1:0,25,29,42,45,r|
LogP 7.830 (est)
CAS DataBase Reference 3351-86-8(CAS DataBase Reference)
EWG's Food Scores 4
FDA UNII 06O0TC0VSM

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P280-P305+P351+P338-P337+P313-P403+P235
Hazard Codes  F
Risk Statements  11
Safety Statements  7-16-24/25
RIDADR  UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany  3
HS Code  29153900
NFPA 704
0
2 0

Fucoxanthin price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 16337 Fucoxanthin analytical standard 3351-86-8 1mg $95.8 2024-03-01 Buy
Sigma-Aldrich 16337 Fucoxanthin analytical standard 3351-86-8 5mg $258 2024-03-01 Buy
Cayman Chemical 13068 Fucoxanthin ≥95% 3351-86-8 5mg $86 2024-03-01 Buy
Cayman Chemical 13068 Fucoxanthin ≥95% 3351-86-8 10mg $152 2024-03-01 Buy
Sigma-Aldrich F6932 Fucoxanthin carotenoid antioxidant 3351-86-8 10mg $211 2024-03-01 Buy
Product number Packaging Price Buy
16337 1mg $95.8 Buy
16337 5mg $258 Buy
13068 5mg $86 Buy
13068 10mg $152 Buy
F6932 10mg $211 Buy

Fucoxanthin Chemical Properties,Uses,Production

Description

Fucoxanthin is another important xanthophyll. It is widely found in heterokontophyta, such as brown algae and oceanic microalgae,and is believed be the second-most abundant carotenoid on Earth after β-carotene. Recently, studies on the functionality of fucoxanthin have been increasingly conducted,and fucoxanthin has been shown to possess various beneficial physiological activities.It has various pharmaceutical effects such as anti-tumor, anti-inflammatory, anti-oxidant, anti-obesity effects, protecting nerve cell, increasing the content of ARA(arachidonic acid) and DHA (docosahexaenoic acid) in mice; It is widely used as medicine, skin care and beauty industry, and in the Food supplements market.

Chemical Properties

Fucoxanthin is an orange-colored pigment, along with chlorophylls a and c and β-carotene, present in Chromophyta (Heterokontophyta or Ochrophyta), including brown seaweeds (Phaeophyceae) and diatoms (Bacillariophyta). It is insoluble in water but soluble in organic solvents such as ethanol; it is typically lipid-soluble powder or oil.

Occurrence

Fucoxanthin is a xanthophyll carotenoid abundant in macroalgae, such as brown seaweeds and microalgae. Several edible brown algae, including Sargassam fusiforme, Laminaria japonica, Undaria pinnatifida, and Padina tetrastromatica, are consumed in Southeast Asia and Europe. The brown algae are good sources of fucoxanthin. However, diatoms, such as Phaeodactylum tricornutum, are preferred sources of fucoxanthin in the food industry because of their higher fucoxanthin content and extraction efficiency with shorter growth cycles than those of macroalgae[1].

Uses

Fucoxanthin has been used to study its neuroprotective effects. It has also been used in calibration to identify the most efficient fucoxanthin producing strains of microalgae.

Uses

Fucoxanthin is a carotenoid that occurs naturally in certain algae. It significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet. Fucoxanthin increases the amount of mitochondrial uncoupling protein 1 (UCP1), a fatty acid-stimulated protein involved in respiration and thermogenesis in WAT of mice and rats. In KK-Ay mice, which are used to model obese type 2 diabetics with hyperinsulinemia, fucoxanthin reduces WAT gain and also decreases blood glucose and plasma insulin levels.

Uses

Fucoxanthin is a carotenoid pigment found in fresh brown algae.It can be used as an anti-obesity, anticancer, anti-cholesterol, and anti-diabetic agent and as a food colorant, but it is very unstable. It is easily affected by heating, aerial exposure, and illumination.

Definition

ChEBI: A natural product found in Sporochnus comosus.

General Description

Fucoxanthin is isolated from brown algae. It has anti-angiogenic, hepatoprotective,?cardiovascular and cerebrovascular protective properties. Fucoxanthin stimulates G1 cell-cycle arrest and apoptosis in cancer cell lines.

Biochem/physiol Actions

Xanthophyll carotenoid pigment extracted from algae. Exhibits anticancer, antioxidant, anti-obesity and anti-inflammatory properties.

Side effects

There are some potential dangers associated with taking Fucoxanthin. These include an increased risk of bleeding, liver damage, and allergic reactions. Additionally, it may interact with certain medications, such as blood thinners, and can cause side effects such as nausea, vomiting, and diarrhea.

Metabolism

Fucoxanthin is unstable and can be easily degraded by heating, aerial exposure, or illumination. The primary metabolites of fucoxanthin are fucoxanthinol and amarouciaxanthin A. Fucoxanthin can be hydrolyzed to fucoxanthinol in the gastrointestinal tract and further converted into amarouciaxanthin A in the liver. In animal studies, no toxicity of fucoxanthin was observed [1].

References

[1] Minkyung Bae . “Health benefits of fucoxanthin in the prevention of chronic diseases.” Biochimica et biophysica acta. Molecular and cell biology of lipids 1865 11 (2020): Article 158618.

Fucoxanthin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 229)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 282 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253 jancyzheng@gcgreenpure.com China 952 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58

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View Lastest Price from Fucoxanthin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fucoxanthin; Kelp extract pictures 2024-04-23 Fucoxanthin; Kelp extract
3351-86-8
US $0.00 / G 1G ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Fucoxanthin pictures 2024-04-22 Fucoxanthin
3351-86-8
US $0.00 / kg 1kg 99.8% 1000 kg BINBO BIOLOGICAL CO.,LTD
Fucoxanthin pictures 2024-01-04 Fucoxanthin
3351-86-8
US $0.00-0.00 / kg 1kg 99% 50000kg Hebei Yibangte Import and Export Co. , Ltd.
  • Fucoxanthin pictures
  • Fucoxanthin
    3351-86-8
  • US $0.00 / kg
  • 99.8%
  • BINBO BIOLOGICAL CO.,LTD
  • Fucoxanthin pictures
  • Fucoxanthin
    3351-86-8
  • US $0.00-0.00 / kg
  • 99%
  • Hebei Yibangte Import and Export Co. , Ltd.
Fucoxanthin, froM LaMinariajaponicaAresch Fucoxanthin solution (3S,3'S,5R,5'R,6S,6'R)-6',7'-Didehydro-5,6-epoxy-4',5',6,7-tetrahydro-3,3',5'-trihydroxy-,-caroten-8(5H)-one all-trans-Fucoxanthin Fucoxanthin DISCONTINUED (3S,3'S,5R,5'R,6S,6'R)- Fucoxanthol beta,beta-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)- Brn 0073179 Ccris 4055 FUCOXANTHIN, CAROTENOID ANTIOXIDANT (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5,5',6-Tetrahydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-β,β-caroten-3'-yl acetate (3s,3’s,5r,5’r,6s,6’r)-hydro-5’-dihydroxy-8-oxo- beta,beta-carotene,3’-(acetyloxy)-6’,7’-didehydro-5,6-epoxy-5,5’,6,6’,7,8-hexa 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-beta,beta-carotene FUCOXANTHIN 6'R,7'-didehydro-5R,6-epoxy-4',5',6S,7-tetrahydro-3S,3'S,5'R-trihydroxy-β,β-caroten-8(5H)-one Fucoxanthin, 98%, from Laminaria japonica Aresch β,β-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)- Fucoxanthin (10%) Fuconxanthin(P) β,β-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)- 3351-86-8 C40H60O6 C42H58O6 C42H60O7 Herb extract Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals