(2'S)-Nicotine 1-Oxide
- CAS No.
- 2820-55-5
- Chemical Name:
- (2'S)-Nicotine 1-Oxide
- Synonyms
- (2'S)-Nicotine 1-Oxide;Acrylamide Impurity 17;(S)-nicotine 1-N-oxide;(S)-3-(1-Methyl-2-pyrrolidinyl)pyridine 1-Oxide;3-(1-methylpyrrolidin-2-yl)-1-oxidopyridin-1-ium;3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium;3-[(2S)-1-Methyl-2α-pyrrolidinyl]pyridine 1-oxide;Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, 1-oxide;3-(1-methylpyrrolidin-2-yl)-1-oxidanidyl-pyridin-1-ium
- CBNumber:
- CB11175320
- Molecular Formula:
- C10H14N2O
- Molecular Weight:
- 178.23
- MDL Number:
- MOL File:
- 2820-55-5.mol
| Boiling point | 347.9±30.0 °C(Predicted) |
|---|---|
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| solubility | DMF: 50 mg/mL; DMSO: 30 mg/mL; Ethanol: 50 mg/mL; PBS (pH 7.2): 1 mg/mL |
| form | A crystalline solid |
| pka | 8.79±0.40(Predicted) |
| Stability | Very Hygroscopic |
| CAS DataBase Reference | 2820-55-5 |
| FDA UNII | 8WQ7L5T6TJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
(2'S)-Nicotine 1-Oxide price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22153 | (2'S)-Nicotine-1-oxide ≥98% | 2820-55-5 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 22153 | (2'S)-Nicotine-1-oxide ≥98% | 2820-55-5 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 22153 | (2'S)-Nicotine-1-oxide ≥98% | 2820-55-5 | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 22153 | (2'S)-Nicotine-1-oxide ≥98% | 2820-55-5 | 25mg | $618 | 2024-03-01 | Buy |
| TRC | N428000 | (2''S)-Nicotine1-Oxide | 2820-55-5 | 50mg | $185 | 2021-12-16 | Buy |
(2'S)-Nicotine 1-Oxide Chemical Properties,Uses,Production
Description
(2''S)-Nicotine-1-oxide is a metabolite of nicotine . It is formed when nicotine is metabolized in the liver by cytochrome P450 (CYP) isoform CYP2A6. (2''S)-Nicotine-1-oxide has been detected in human sperm and semen.
Chemical Properties
Light Yellow Crystals
Uses
Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine i
Uses
Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
Definition
ChEBI: A member of the class of pyridine N-oxides obtained by oxidation of the pyridine nitrogen of (S)-nicotine.
(2'S)-Nicotine 1-Oxide Preparation Products And Raw materials
Raw materials
Preparation Products
(2'S)-Nicotine 1-Oxide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55672 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Aikon International Limited | 18626450290 | yftan@aikonchem.com | China | 10718 | 58 |