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2-Iodobenzoic acid

2-Iodobenzoic acid structure

CAS No.: 88-67-5

Chemical Name:: 2-Iodobenzoic acid

Synonyms: O-IODOBENZOIC ACID;2-IODO BENZONIC ACID;NSC 3772;usafek-572;USAF ek-572;'LGC' (4009);O-iodine acid;IodobenzoicAcid;2-iodo-benzoicaci;o-iodo-benzoicaci

CBNumber:: CB1126640

Molecular Formula:: C7H5IO2

Molecular Weight:: 248.02

MDL Number:: MFCD00002419

MOL File:: 88-67-5.mol

MSDS File:: SDS

Last updated:2023-12-24 16:54:11

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2-Iodobenzoic acid Properties

Melting point	160-162 °C(lit.)
Boiling point	313.9±25.0 °C(Predicted)
Density	2.25
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in dimethyl sulfoxide and methanol
pka	2.85(at 25℃)
form	Powder, Crystals or Flakes
color	Light yellow to orange-brown
Water Solubility	sparingly soluble
Sensitive	Light Sensitive
Merck	14,5030
BRN	1861406
Stability	Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey	CJNZAXGUTKBIHP-UHFFFAOYSA-N
CAS DataBase Reference	88-67-5(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	7Q00V80J7Q
NIST Chemistry Reference	Benzoic acid, 2-iodo-(88-67-5)
EPA Substance Registry System	Benzoic acid, 2-iodo- (88-67-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H318-H335

Precautionary statements

P261-P264-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

22-37/38-41-36/37/38-20/21/22

Safety Statements

26-39-24/25-22-36

WGK Germany

RTECS

DH2975000

Hazard Note

Irritant

TSCA

HazardClass

IRRITANT, LIGHT SENSITIVE

HS Code

29163900

NFPA 704

	1
2		0

2-Iodobenzoic acid price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	I7675	2-Iodobenzoic acid 98%	88-67-5	25g	$28.4	2024-03-01	Buy
Sigma-Aldrich	418463	2-Iodobenzoic acid ≥99%, purified by sublimation	88-67-5	1G	$34.6	2023-01-07	Buy
TCI Chemical	I0053	2-Iodobenzoic Acid >98.0%(GC)(T)	88-67-5	25g	$26	2024-03-01	Buy
TCI Chemical	I0053	2-Iodobenzoic Acid >98.0%(GC)(T)	88-67-5	100g	$73	2024-03-01	Buy
Alfa Aesar	A10563	2-Iodobenzoic acid, 98+%	88-67-5	25g	$23.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
I7675	25g	$28.4	Buy
418463	1G	$34.6	Buy
I0053	25g	$26	Buy
I0053	100g	$73	Buy
A10563	25g	$23.65	Buy

2-Iodobenzoic acid Chemical Properties,Uses,Production

Description

2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction.

Chemical Properties

white crystal powder. Soluble in alcohol and ether, insoluble in water.

Uses

Reagent for detection of sulfhydryl groups in proteins. 2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.

Preparation

2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water.

Definition

ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position.

Synthesis Reference(s)

Journal of the American Chemical Society, 93, p. 4841, 1971 DOI: 10.1021/ja00748a029

Purification Methods

Crystallise the acid repeatedly from water and EtOH. Sublime it under vacuum at 100o. [Beilstein 9 IV 1030.]

2-Iodobenzoic acid synthesis

Synthesis of 2-Iodobenzoic acid from 2-IODOBENZALDEHYDE

2-Iodobenzoic acid Preparation Products And Raw materials

Raw materials

Anthranilic acid 2-Iodobenzoic acid phenacyl ester Benzenediazonium, 2-iodo-, tetrafluoroborate(1-) 2-Iodobenzyl alcohol 2-IODOBENZALDEHYDE

2-IODOSTYRENE t-Butyl2-iodobenzoate Methyl 2-iodobenzoate

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Preparation Products

2-IODOBENZOYL CHLORIDE Dess-Martin periodinane 2-Iodoxybenzoic acid 2'-IODOHIPPURIC ACID Flufenamic acid

2-Ethoxycarbonylphenylboronic acid pinacol ester 1-Hydroxy-2-oxa-1-ioda(III)indan-3-one 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Methyl 2-(2-iodophenyl)acetate N-(2-AMINO-4-CHLOROPHENYL)ANTHRANILIC ACID

5-Bromo-2-iodobenzoic acid

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2-Iodobenzoic acid Suppliers

Global( 634)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Dalian Richfortune Chemicals Co., Ltd	0411-84820922 8613904096939	sales@richfortunechem.com	China	303	57
Mascot I.E.Co .,Ltd.			China	303	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12457	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7613	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55

Supplier	Advantage
Dalian Richfortune Chemicals Co., Ltd	57
Mascot I.E.Co .,Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55

2-Iodobenzoic acid: properties and applications in organic synthesis
2-Iodobenzoic acid is a versatile compound used in organic synthesis for various reactions.
Sep 11，2023

What is the 2-Iodobenzoic acid?Uses,Synthesis,Purification Methods
2-Iodobenzoic acid, or o-iodobenzoic acid, is a white crystal powder, It is an organic compound with the formulaI C6H4COOH. Th....
Aug 14，2020

View Lastest Price from 2-Iodobenzoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-12	2-Iodobenzoic acid 88-67-5	US $0.00-0.00 / KG	1KG	99%	10000 Mt/Year	Shaanxi Haibo Biotechnology Co., Ltd
2024-04-12	2-Iodobenzoic acid 88-67-5	US $0.00 / kg	1kg	99%	2000ton	Shaanxi Haibo Biotechnology Co., Ltd
2024-01-02	2-Iodobenzoic acid 88-67-5	US $75.00-750.00 / KG	1KG	0.99	20 tons	Zibo Hangyu Biotechnology Development Co., Ltd

2-Iodobenzoic acid
88-67-5
US $0.00-0.00 / KG
99%
Shaanxi Haibo Biotechnology Co., Ltd

2-Iodobenzoic acid
88-67-5
US $0.00 / kg
99%
Shaanxi Haibo Biotechnology Co., Ltd

2-Iodobenzoic acid
88-67-5
US $75.00-750.00 / KG
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

2-Iodobenzoic acid Spectrum

2-Iodobenzoic acid(88-67-5)MS 2-Iodobenzoic acid(88-67-5)¹HNMR 2-Iodobenzoic acid(88-67-5)¹³CNMR 2-Iodobenzoic acid(88-67-5)IR1 2-Iodobenzoic acid(88-67-5)IR2 2-Iodobenzoic acid(88-67-5)Raman

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RARECHEM AL BO 0686 2-IODOBENZOIC ACID BENZOIC ACID, 2-IODO- 'LGC' (4009) IODOBENZOIC-2 ACID 2-IODOBENZOIC ACID pure 2-(Hydroxycarbonyl)phenyliodine 2-Iodobenzoic acid, 98% 100GR 2-Iodobenzoic acid, 98% 25GR o-Iodobenzenecarboxylic acid O-iodine acid NSC 3772 2-Iodobenzoic Acid, 97+% Adjacent iodine benzoic acid 2-Iodobenzoic acid >=99%, purified by sublimation 2-iodo-benzoicaci Benzoic acid, o-iodo- Kyselina o-jodbenzoova kyselinao-jodbenzoova o-iodo-benzoicaci o-lodobenzoicacid USAF ek-572 usafek-572 ACID O-IODOBENZOIC o-Iodobenzoic Acid 2-Iodobenzoic acid 2-IODOBENZOIC ACID, SUBLIMED, 99+% IodobenzoicAcid 2-Iodobenzoic acid, 98+% ORTHO-IODOSOBENZOICACID 2-IODOBENZOIC ACID 88-67-5 2-IodobenzoicAcid> 2-Iodobenzoic acid, 98%, for synthesis 2-Iodobenzoic acid (Stellar-2003) 2-IODOBENZOIC ACID For Synthesis O-IODOBENZOIC ACID 2-IODO BENZONIC ACID Aniodobenzoic acid Metronidazole Impurity 16(Secnidazole)-d6 2 Iodo Benzoic Acid (O-Iodobenzoic Acid) 88-67-5 98-67-5 IC6H4COOH 2IC6H4CO2H CARBOXYLIC ACID Organic Building Blocks Building Blocks C7 Carbonyl Compounds Carboxylic Acids Aromatics Building Blocks Carbonyl Compounds Carboxylic Acids Chemical Synthesis Organic Building Blocks C7 Carbonyl Compounds Carboxylic Acids